Faculty Opinions recommendation of Mitochondrial Hsp60, resistance to oxidative stress, and the labile iron pool are closely connected in Saccharomyces cerevisiae.

2002 ◽  
Author(s):  
Thomas Nystrom
Keyword(s):  
Oxidative Stress ◽  
Saccharomyces Cerevisiae ◽  
Labile Iron Pool ◽  
Labile Iron ◽  
Iron Pool

scholarly journals Oxidative stress and disruption of labile iron generate specific auxotrophic requirements in Salmonella enterica

Microbiology ◽  
2009 ◽  
Vol 155 (1) ◽  
pp. 295-304 ◽  
Author(s):  
Michael P. Thorgersen ◽  
Diana M. Downs
Keyword(s):  
Oxidative Stress ◽  
Mutant Strain ◽  
Iron Homeostasis ◽  
Sulfite Reductase ◽  
Nutritional Requirements ◽  
Labile Iron Pool ◽  
Genetic Perturbations ◽  
A Cell ◽  
Labile Iron ◽  
Iron Pool

The response of a cell to integrated stresses was investigated using environmental and/or genetic perturbations that disrupted labile iron homeostasis and increased oxidative stress. The effects of the perturbations were monitored as nutritional requirements, and were traced to specific enzymic targets. A yggX gshA cyaY mutant strain required exogenous thiamine and methionine for growth. The thiamine requirement, which had previously been linked to the Fe–S cluster proteins ThiH and ThiC, was responsive to oxidative stress and was not directly affected by manipulation of the iron pool. The methionine requirement was associated with the activity of sulfite reductase, an enzyme that appeared responsive to disruption of labile iron homeostasis. The results are incorporated in a model to suggest how the activity of iron-containing enzymes not directly sensitive to oxygen can be decreased by oxidation of the labile iron pool.

scholarly journals Labile iron pool as a parameter to monitor iron overload and oxidative stress status in β-thalassemic erythrocytes

2018 ◽  
Vol 94 (4) ◽  
pp. 631-636 ◽  
Author(s):  
Boonyanuch Chutvanichkul ◽  
Phantip Vattanaviboon ◽  
Sumana Mas-oodi ◽  
Yaowalak U-pratya ◽  
Wanchai Wanachiwanawin
Keyword(s):  
Oxidative Stress ◽  
Iron Overload ◽  
Labile Iron Pool ◽  
Oxidative Stress Status ◽  
Labile Iron ◽  
Iron Pool ◽  
And Oxidative Stress

scholarly journals Green tea extract and epigallocatechin 3-gallate reduced labile iron pool and protected oxidative stress in iron-loaded cultured hepatocytes

2012 ◽  
Vol 03 (08) ◽  
pp. 1140-1150 ◽  
Author(s):  
Somdet Srichairatanakool ◽  
Kanokwan Kulprachakarn ◽  
Kanjana Pangjit ◽  
Kovit Pattanapanyasat ◽  
Suthat Fuchaeron
Keyword(s):  
Oxidative Stress ◽  
Green Tea ◽  
Green Tea Extract ◽  
Cultured Hepatocytes ◽  
Labile Iron Pool ◽  
Labile Iron ◽  
Iron Pool ◽  
Tea Extract

Downregulation of ferritin heavy chain increases labile iron pool, oxidative stress and cell death in cardiomyocytes

2009 ◽  
Vol 46 (1) ◽  
pp. 59-66 ◽  
Author(s):  
Shigemiki Omiya ◽  
Shungo Hikoso ◽  
Yukiko Imanishi ◽  
Atsuhiro Saito ◽  
Osamu Yamaguchi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cell Death ◽  
Heavy Chain ◽  
Labile Iron Pool ◽  
Ferritin Heavy Chain ◽  
Labile Iron ◽  
Iron Pool

scholarly journals Mitochondrial Hsp60, Resistance to Oxidative Stress, and the Labile Iron Pool Are Closely Connected inSaccharomyces cerevisiae

2002 ◽  
Vol 277 (46) ◽  
pp. 44531-44538 ◽  
Author(s):  
Elisa Cabiscol ◽  
Gemma Bellı́ ◽  
Jordi Tamarit ◽  
Pedro Echave ◽  
Enrique Herrero ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Labile Iron Pool ◽  
Labile Iron ◽  
Iron Pool
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