green tea extract
Recently Published Documents


TOTAL DOCUMENTS

1170
(FIVE YEARS 327)

H-INDEX

62
(FIVE YEARS 9)

Author(s):  
Dilek Çavuşoğlu ◽  
Oksal Macar ◽  
Tuğçe Kalefetoğlu Macar ◽  
Kültiğin Çavuşoğlu ◽  
Emine Yalçın

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Camila Taise Tavares ◽  
Alline Cristina Schüncke Lobo ◽  
Cláudia Choma Bettega Almeida ◽  
Adriano Eduardo Lima-Silva ◽  
Sila Mary Rodrigues Ferreira

Author(s):  
Yu-Wen Hsu ◽  
Wen-Kang Chen ◽  
Chia-Fang Tsai

This study investigates the catechin composition and protective effect of green tea extract on senescence-mediated redox imbalance in the livers and kidneys of aged mice. The results showed that the seven catechins in the green tea extract analyzed in this study could be completely separated within 30 min and the main components of catechins in green tea extract were EGCG, EGC and ECG. In terms of the anti-senescence effects of green tea extract, green tea extract supplementation at doses of 125, 625 and 1250 mg/kg for 4 weeks significantly alleviated the senescence-mediated redox imbalance, as exhibited from significantly (p < 0.05) reduced thiobarbituric acid-reactive substances (TBARS) and protein carbonyls levels in the serum, and increased glutathione (GSH) and total thiols contents in the plasma. Additionally, hepatic and renal protein carbonyls levels were significantly diminished (p < 0.05) and the activities of superoxide dismutase (SOD), catalase, glucose-6-phosphate dehydrogenase (G6PD), glutathione peroxidase (GSH-Px) and glutathione reductase (GSH-Rd) in the liver and kidney were remarkably elevated (p < 0.05). Overall, these results clearly show that green tea extract exhibits extremely potent protective effects against senescence-mediated redox imbalance in the livers and kidneys of mice by inhibiting oxidative damage of lipids and proteins and increasing the activities of antioxidant enzymes in organs.


2021 ◽  
Vol 54 (12) ◽  
pp. 638-647
Author(s):  
Bimala Pangeni ◽  
Hari Paudyal ◽  
Katsutoshi Inoue ◽  
Keisuke Ohto ◽  
Hidetaka Kawakita

2021 ◽  
Vol 4 (IAHSC) ◽  
pp. 1-11
Author(s):  
Ajeng Ayu Pebriani ◽  
Maya Uzia Beandrade

Introduction: Black glutinous rice (Oriza sativa var glutinosa) and green tea (Camelia sinensis) are plants that are useful for moisturizing the skin. The purpose of this study was to obtain the best formulation of peel-off gel mask preparations from black glutinous rice and green tea extract. Method: The gel mask formulation was made on the basis of variations in the concentration of Hydroxy Propyl Methyl Cellulose (HPMC) of F1 (2,5%), F2 (3%) and F3 (3,5%) with evaluation including organoleptic tests, pH, viscosity, homogenity, dispersity test, and drying time at temperatures of 4oC, 25oC, 40oC for 28 days. Results: The evaluation results of the three formulations met the requirements for a good peel-off gel mask. pH results are between 4.6-5.5 which is still in the standard range of 4.5-6.0. The results of the viscosity test are 6.500-12.166.7 cps which are in the range of 6.000-24.000 cps, the dispersion area meets the requirements of 5-7 cm, the result of the drying time is 15-22 minutes which are in the range of 15-30 minutes. Conclusion: The conclusion of this study was that F1, F2, and F3 met all the requirements for peel off gel masks by storing at temperatures of 4oC, 25oC, 40oC for 28 days.


Author(s):  
Rafael Sepúlveda Fonsêca Trevisan Passos ◽  
Brenno Guimarães Barreto ◽  
Juliana Sant’Ana Falcão Leite ◽  
Adrielle Bahiense Trevisan ◽  
Carolina Oliveira de Souza ◽  
...  

Pathogens ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1573
Author(s):  
Jeong-Won Kim ◽  
Chang-Yeop Kim ◽  
Jin-Hwa Kim ◽  
Ji-Soo Jeong ◽  
Je-Oh Lim ◽  
...  

In this study, we explored the potential beneficial effects of green tea extract (GTE) in a pathogenic Escherichia coli (F18:LT:STa:Stx2e)-induced colitis model. The GTE was standardized with catechin and epigallocatechin-3-gallate content using chromatography analysis. Ten consecutive days of GTE (500 and 1000 mg/kg) oral administration was followed by 3 days of a pathogenic E. coli challenge (1 × 109 CFU/mL). In vitro antibacterial analysis showed that GTE successfully inhibited the growth of pathogenic E. coli, demonstrating over a 3-fold reduction under time- and concentration-dependent conditions. The in vivo antibacterial effect of GTE was confirmed, with an inhibition rate of approximately 90% when compared to that of the E. coli alone group. GTE treatment improved pathogenic E. coli-induced intestinal injury with well-preserved epithelial linings and villi. In addition, the increased expression of annexin A1 in GTE-treated jejunum tissue was detected, which was accompanied by suppressed inflammation-related signal expression, including TNFA, COX-2, and iNOS. Moreover, proliferation-related signals such as PCNA, CD44, and Ki-67 were enhanced in the GTE group compared to those in the E. coli alone group. Taken together, these results indicate that GTE has an antibacterial activity against pathogenic E. coli and ameliorates pathogenic E. coli-induced intestinal damage by modulating inflammation and epithelial cell proliferation.


F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 1175
Author(s):  
Ermin Rachmawati ◽  
Mohammad Saifur Rohman ◽  
Djanggan Sargowo ◽  
Umi Kalsum ◽  
Diana Lyrawati ◽  
...  

Background: Foam cells are markers of atherosclerosis and characterise advanced atherosclerotic plaque, stimulated by inflammation caused by high lipid levels in macrophages. The combination of decaffeinated coffee and green tea extract (DCGTE) has been suggested to have a role in foam cell inhibition. Objective: we investigated the inhibiting role of DCGTE against foam cell formation, through modulation of the inflammation process and cholesterol metabolism in macrophage colony stimulating factor- (M-CSF) and oxidized low-density lipoprotein (oxLDL)-exposed macrophages. Methods: Coffee and green tea were extracted by filtration and infusion respectively, and underwent decaffeination using active carbon and blanching methods, respectively. Cells were administered 160/160 and 320/320μg/ml of DCGTE. Foam cell formation was observed using a light microscope after staining with Oil Red O (ORO), and the accumulation of lipids in macrophages with ELISA. Observations of lipid influx and efflux were determined through semiquantitative cluster differentiation 36 (CD36) and ATP binding cassette transporter A1 (ABCA1) expression through immunofluorescence. The inflammation process was quantified using inflammatory/anti-inflammatory markers, e.g., tumor necrosis factor α (TNFα) and interleukin 10 (IL10) with ELISA. Peroxisome proliferator activated response γ (PPARγ) expression and activity were assessed with PCR and ELISA, respectively. The expression of microRNA 155 (miR-155) was examined using qPCR. Results: DCGTE at the above concentrations tended to reduce foam cell numbers, significantly inhibited lipid accumulation (p=0.000), reduced CD36 expression (p=0.000) and TNFα secretion (p=0.000) in Raw264.7 exposed to M-CSF 50ng/ml and oxLDL 50μg/ml.  PPARγ expression (p=0.00) and activity (p=0.001), miR-155 relative expression (p=0.000), and IL10 production (p=0.000) also increased. Conclusion: DCGTE lowered foam cell numbers, possibly through attenuation of the inflammatory process and improvement of lipid/efflux mechanisms in M-CSF and oxLDL-stimulated Raw264.7 cells, via upregulation of PPARγ and miR-155.  Our results suggest DCGTE may help prevent atherosclerosis-based diseases.


Sign in / Sign up

Export Citation Format

Share Document