Faculty Opinions recommendation of Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes.

2004 ◽  
Author(s):  
Jim Maher
Keyword(s):  
Specific Protein ◽  
Dna Complexes

scholarly journals Context-Dependent Remodeling of Rad51–DNA Complexes by Srs2 Is Mediated by a Specific Protein–Protein Interaction

2014 ◽  
Vol 426 (9) ◽  
pp. 1883-1897 ◽  
Author(s):  
Anna K. Lytle ◽  
Sofia S. Origanti ◽  
Yupeng Qiu ◽  
Jeffrey VonGermeten ◽  
Sua Myong ◽  
...  
Keyword(s):  
Protein Interaction ◽  
Specific Protein ◽  
Dna Complexes ◽  
Protein Protein Interaction ◽  
Context Dependent

scholarly journals Protein-DNA Complexes in Mycobacteriophage L5 Integrative Recombination

1999 ◽  
Vol 181 (2) ◽  
pp. 454-461 ◽  
Author(s):  
Carol E. A. Peña ◽  
J. Michelle Kahlenberg ◽  
Graham F. Hatfull
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Mycobacterium Bovis ◽  
Binding Sites ◽  
Mycobacterium Smegmatis ◽  
Recombination Event ◽  
Specific Protein ◽  
Integration Host Factor ◽  
Dna Complexes ◽  
Active Complex ◽  
Mycobacteriophage L5

ABSTRACT The temperate mycobacteriophage L5 integrates site specifically into the genomes of Mycobacterium smegmatis,Mycobacterium tuberculosis, and Mycobacterium bovis bacillus Calmette-Guérin. This integrative recombination event occurs between the phage L5 attP site and the mycobacterial attB site and requires the phage-encoded integrase and mycobacterial-encoded integration host factor mIHF. Here we show that attP, Int-L5, and mIHF assemble into a recombinationally active complex, the intasome, which is capable of attB capture and formation of products. The arm-type integrase binding sites within attP play specialized roles in the formation of specific protein-DNA architectures; the intasome is constructed by the formation of intramolecular integrase bridges between one pair of sites, P4-P5, and the attP core, while an additional pair of sites, P1-P2, is required for interaction with attB.

Role of the hydrophobic effect in stability of site-specific protein-DNA complexes

1989 ◽  
Vol 209 (4) ◽  
pp. 801-816 ◽  
Author(s):  
Jeung-Hoi Ha ◽  
Ruth S. Spolar ◽  
M.Thomas Record
Keyword(s):  
Hydrophobic Effect ◽  
Specific Protein ◽  
Dna Complexes ◽  
Site Specific
Sign in / Sign up

Export Citation Format

Share Document