Faculty Opinions recommendation of Employing libraries of zinc finger artificial transcription factors to screen for homologous recombination mutants in Arabidopsis.

2006 ◽  
Author(s):  
Carlos F Barbas
Keyword(s):  
Transcription Factors ◽  
Homologous Recombination ◽  
Zinc Finger ◽  
Artificial Transcription Factors

scholarly journals Development of Zinc Finger Domains for Recognition of the 5′-CNN-3′ Family DNA Sequences and Their Use in the Construction of Artificial Transcription Factors

2005 ◽  
Vol 280 (42) ◽  
pp. 35588-35597 ◽  
Author(s):  
Birgit Dreier ◽  
Roberta P. Fuller ◽  
David J. Segal ◽  
Caren V. Lund ◽  
Pilar Blancafort ◽  
...  
Keyword(s):  
Transcription Factors ◽  
Zinc Finger ◽  
Dna Sequences ◽  
Artificial Transcription Factors ◽  
Zinc Finger Domains

scholarly journals Phenotypic Alteration and Target Gene Identification Using Combinatorial Libraries of Zinc Finger Proteins in Prokaryotic Cells

2005 ◽  
Vol 187 (15) ◽  
pp. 5496-5499 ◽  
Author(s):  
Kyung-Soon Park ◽  
Young-Soon Jang ◽  
Horim Lee ◽  
Jin-Soo Kim
Keyword(s):  
Transcription Factors ◽  
Zinc Finger ◽  
Chromatin Immunoprecipitation ◽  
Target Gene ◽  
Combinatorial Libraries ◽  
Artificial Transcription Factors ◽  
Phenotypic Alteration ◽  
Target Dna ◽  
Genomic Studies ◽  
Phenotypic Variations

ABSTRACT We have developed a method with prokaryotic organisms that uses randomized libraries of zinc finger-containing artificial transcription factors to induce phenotypic variations and to identify genes involved in the generation of a specific phenotype of interest. Combining chromatin immunoprecipitation experiments and in silico prediction of target DNA binding sequences for the artificial transcription factors, we identified ubiX, whose down-regulation correlates with the thermotolerance phenotype in Escherichia coli. Our results show that randomized libraries of artificial transcription factors are powerful tools for functional genomic studies.

scholarly journals Artificial Transcription Factors Based on Multi-zinc Finger Motifs

2010 ◽  
Vol 130 (1) ◽  
pp. 45-48 ◽  
Author(s):  
Tatsuya MORISAKI ◽  
Miki IMANISHI ◽  
Shiroh FUTAKI ◽  
Yukio SUGIURA
Keyword(s):  
Transcription Factors ◽  
Zinc Finger ◽  
Artificial Transcription Factors ◽  
Zinc Finger Motifs

ChemInform Abstract: Artificial Transcription Factors Based on Multi-Zinc Finger Motifs

ChemInform ◽  
2010 ◽  
Vol 41 (22) ◽  
pp. no-no
Author(s):  
Tatsuya Morisaki ◽  
Miki Imanishi ◽  
Shiroh Futaki ◽  
Yukio Sugiura
Keyword(s):  
Transcription Factors ◽  
Zinc Finger ◽  
Artificial Transcription Factors ◽  
Zinc Finger Motifs
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