Faculty Opinions recommendation of Segregation of open Major Histocompatibility Class I conformers at the plasma membrane and during endosomal trafficking reveals conformation-based sorting in the endosomal system.

2011 ◽  
Author(s):  
Joyce Solheim ◽  
Laura Simone
Keyword(s):  
Plasma Membrane ◽  
Class I ◽  
Endosomal Trafficking ◽  
Major Histocompatibility ◽  
Major Histocompatibility Class ◽  
Endosomal System ◽  
Major Histocompatibility Class I

scholarly journals Endosomal trafficking of open Major Histocompatibility Class I conformers—Implications for presentation of endocytosed antigens

2013 ◽  
Vol 55 (2) ◽  
pp. 149-152 ◽  
Author(s):  
Hana Mahmutefendić ◽  
Gordana Blagojević Zagorac ◽  
Maja Ilić Tomaš ◽  
Marcus Groettrup ◽  
Frank Momburg ◽  
...  
Keyword(s):  
Class I ◽  
Endosomal Trafficking ◽  
Major Histocompatibility ◽  
Major Histocompatibility Class ◽  
Major Histocompatibility Class I

scholarly journals Enhancement of major histocompatibility class I protein synthesis by DNA damage in cultured human fibroblasts and keratinocytes.

1989 ◽  
Vol 9 (2) ◽  
pp. 847-850 ◽  
Author(s):  
M E Lambert ◽  
Z A Ronai ◽  
I B Weinstein ◽  
J I Garrels
Keyword(s):  
Dna Damage ◽  
Protein Synthesis ◽  
Human Fibroblasts ◽  
Simian Virus 40 ◽  
Class I ◽  
Major Histocompatibility ◽  
Class I Mhc ◽  
Mhc I ◽  
Major Histocompatibility Class ◽  
Major Histocompatibility Class I

Exposure of primary human fibroblasts or simian virus 40-transformed human keratinocytes to several different classes of DNA damage, including UV light C (254 nm), resulted in a rapid increase in the expression of human major histocompatibility class I (MHC-I) proteins. MHC-I induction was also detected after exposure to low doses of the protein synthesis inhibitor cycloheximide, suggesting that MHC-I induction by DNA damage may be a component in a derepressible cellular SOS pathway.

T-Cell Tolerance in Transgenic Mice Expressing Major Histocompatibility Class I Molecules in Defined Tissues

1989 ◽  
Vol 107 (1) ◽  
pp. 109-124 ◽  
Author(s):  
Jacques F. A. P. Miller ◽  
Grant Morahan ◽  
Janette Allison ◽  
Prithi S. Bhathal ◽  
Kerry O. Cox
Keyword(s):  
T Cell ◽  
Transgenic Mice ◽  
Class I ◽  
T Cell Tolerance ◽  
Cell Tolerance ◽  
Major Histocompatibility ◽  
Major Histocompatibility Class ◽  
Major Histocompatibility Class I
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