Faculty Opinions recommendation of Diet and the evolution of human amylase gene copy number variation.

Author(s):  
Magnus Ingelman-Sundberg
2018 ◽  
Vol 13 (4) ◽  
pp. 193-205 ◽  
Author(s):  
Patrick J.D. Elder ◽  
David B. Ramsden ◽  
David Burnett ◽  
Martin O. Weickert ◽  
Thomas M. Barber

2007 ◽  
Vol 39 (10) ◽  
pp. 1256-1260 ◽  
Author(s):  
George H Perry ◽  
Nathaniel J Dominy ◽  
Katrina G Claw ◽  
Arthur S Lee ◽  
Heike Fiegler ◽  
...  

2021 ◽  
Author(s):  
Thuraya M Mutawi ◽  
Mohamed M Zedan ◽  
Raida S Yahya ◽  
Mahmoud M Zakria ◽  
Mamdouh R El-Sawi ◽  
...  

Aim: This study investigated major allelic variants of CYP2D6, CYP3A4 and CYP3A5 in Egyptians, an Arabic population for which there is little information regarding these important pharmacogenes. Patients & methods: CYP2D6*2, *4, *5, *10, *41 and gene copy number variation, as well as CYP3A4*22 and CYP3A5*3 were determined with commercially available TaqMan assays in 145 healthy study participants. Results: The CYP2D6 alleles identified suggest that the prevalence of poor metabolizers is low as none were found among the 145 subjects investigated. The frequency for CYP3A5 nonexpressers was 74.5% and the CYP3A4*22 allele frequency was low at 2.0%. Conclusion: These preliminary findings indicate that pharmacogene variation in Egyptians is different from those of other Middle Eastern/Arabic populations and warrants further investigation.


2007 ◽  
Vol 96 (1-3) ◽  
pp. 93-99 ◽  
Author(s):  
S SUTRALA ◽  
D GOOSSENS ◽  
N WILLIAMS ◽  
L HEYRMAN ◽  
R ADOLFSSON ◽  
...  

2012 ◽  
Vol 12 (1) ◽  
pp. 177 ◽  
Author(s):  
Bettina E Schirrmeister ◽  
Daniel A Dalquen ◽  
Maria Anisimova ◽  
Homayoun C Bagheri

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