Faculty Opinions recommendation of Antiepileptic drug use and rates of hip bone loss in older men: a prospective study.

2008 ◽  
Author(s):  
Alison Pack ◽  
Elizabeth E Gerard
Keyword(s):  
Drug Use ◽  
Bone Loss ◽  
Prospective Study ◽  
Antiepileptic Drug ◽  
Older Men ◽  
A Prospective Study

scholarly journals Antiepileptic drug use and rates of hip bone loss in older men: A prospective study

Neurology ◽  
2008 ◽  
Vol 71 (10) ◽  
pp. 723-730 ◽  
Author(s):  
K. E. Ensrud ◽  
T. S. Walczak ◽  
T. L. Blackwell ◽  
E. R. Ensrud ◽  
E. Barrett-Connor ◽  
...  
Keyword(s):  
Drug Use ◽  
Bone Loss ◽  
Prospective Study ◽  
Antiepileptic Drug ◽  
Older Men ◽  
A Prospective Study

Antiepileptic drug use increases rates of bone loss in older women: A prospective study

Neurology ◽  
2004 ◽  
Vol 62 (11) ◽  
pp. 2051-2057 ◽  
Author(s):  
K. E. Ensrud ◽  
T. S. Walczak ◽  
T. Blackwell ◽  
E. R. Ensrud ◽  
P. J. Bowman ◽  
...  
Keyword(s):  
Drug Use ◽  
Bone Loss ◽  
Prospective Study ◽  
Antiepileptic Drug ◽  
Older Women ◽  
A Prospective Study

scholarly journals A prospective study of thyroid function, bone loss, and fractures in older men: The MrOS study

2013 ◽  
Vol 28 (3) ◽  
pp. 472-479 ◽  
Author(s):  
Avantika C Waring ◽  
Stephanie Harrison ◽  
Howard A Fink ◽  
Mary H Samuels ◽  
Peggy M Cawthon ◽  
...  
Keyword(s):  
Bone Loss ◽  
Prospective Study ◽  
Thyroid Function ◽  
Older Men ◽  
A Prospective Study

scholarly journals First, do no harm: the risks of overtreating children with epilepsy

2007 ◽  
Vol 65 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Eunice Chuang ◽  
Marilisa M. Guerreiro ◽  
Sara Y. Tsuchie ◽  
Angelica Santucci ◽  
Carlos A. M. Guerreiro ◽  
...  
Keyword(s):  
Adverse Events ◽  
Prospective Study ◽  
Antiepileptic Drug ◽  
Antiepileptic Drugs ◽  
Seizure Frequency ◽  
Seizure Control ◽  
Control Method ◽  
Refractory Epilepsy ◽  
Do No Harm ◽  
A Prospective Study

BACKGROUND: Although overtreatment with antiepileptic drugs contributes to the morbidity associated with epilepsy, many children still are overtreated. OBJECTIVE: To evaluate if the withdrawal of at least one antiepileptic drug (AED) in children with refractory epilepsy using polytherapy enable a better seizure control. METHOD: This was a prospective study. Children with refractory epilepsy using at least two AEDs were included. Once the patient, or guardian, agreed to participate in the study, one or more AED were slowly tapered off. The remaining AEDs dosages could be adjusted as needed, but a new AED could not be introduced. RESULTS: Fifteen patients were evaluated, three girls; ages ranging from 3 to 18 (mean=8.7 years). After at least one AED withdrawal, two (13.5%) patients became seizure free, seizures improved >50% in 5 (33.5%) patients, did not change in 5 (33.5%), and seizure frequency became worse in 3 (20%). Adverse events improved in 12 patients (80%). CONCLUSION: The withdrawal of at least one AED is a valuable option in the treatment of selected children with refractory epilepsy.

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