Faculty Opinions recommendation of A double blind placebo RCT to investigate the effects of serotonergic modulation on brain excitability and motor recovery in stroke patients.

2010 ◽  
Author(s):  
Isabelle Loubinoux
Keyword(s):  
Motor Recovery ◽  
Stroke Patients ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Brain Excitability ◽  
Serotonergic Modulation

Serotonin Versus Levodopa in Ischemic Stroke Patients (SELEIS): A Randomised, Double- Blind, Placebo-Controlled Trial

2021 ◽  
Author(s):  
Dolores D. Cocho ◽  
Jordi J. Espinosa ◽  
Miguel M. Cuadrado ◽  
Carlos C. Segui ◽  
Raquel R. Cuevas ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Controlled Trial ◽  
Stroke Patients ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals Safety and Efficacy of MLC601 in Iranian Patients after Stroke: A Double-Blind, Placebo-Controlled Clinical Trial

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
A. A. Harandi ◽  
R. Abolfazli ◽  
A. Hatemian ◽  
K. Ghragozlee ◽  
M. Ghaffar-Pour ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Ischemic Stroke ◽  
Treatment Group ◽  
Repeated Measures ◽  
Motor Recovery ◽  
Controlled Clinical Trial ◽  
Double Blind ◽  
Safety And Efficacy ◽  
Stroke Treatment ◽  
Double Blind Placebo

Objective. To investigate the safety and efficacy of MLC601 (NeuroAid) as a traditional Chinese medicine on motor recovery after ischemic stroke.Methods. This study was a double-blind, placebo-controlled clinical trial on 150 patients with a recent (less than 1 month) ischemic stroke. All patients were given either MLC601 (100 patients) or placebo (50 patients), 4 capsules 3 times a day, as an add-on to standard stroke treatment for 3 months.Results. Sex, age, elapsed time from stroke onset, and risk factors in the treatment group were not significantly different from placebo group at baseline (P>.05). Repeated measures analysis showed that Fugl-Meyer assessment was significantly higher in the treatment group during 12 weeks after stroke (P<.001). Good tolerability to treatment was shown, and adverse events were mild and transient.Conclusion. MLC601 showed better motor recovery than placebo and was safe on top of standard ischemic stroke medications especially in the severe and moderate cases.

A double-blind placebo-controlled study of sertraline in the prevention of depression in stroke patients

2002 ◽  
Vol 12 ◽  
pp. 231 ◽  
Author(s):  
A. Rasmussen ◽  
M. Lunde ◽  
K. Sorensen ◽  
S. Qvitzau ◽  
P. Bech
Keyword(s):  
Controlled Study ◽  
Stroke Patients ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals Baclofen for stroke patients with persistent hiccups: a randomized, double-blind, placebo-controlled trial

Trials ◽  
2014 ◽  
Vol 15 (1) ◽  
Author(s):  
Cuie Zhang ◽  
Ruifen Zhang ◽  
Shuangyan Zhang ◽  
Meiling Xu ◽  
Shuyan Zhang
Keyword(s):  
Controlled Trial ◽  
Stroke Patients ◽  
Double Blind ◽  
Double Blind Placebo
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