Faculty Opinions recommendation of Rethinking clinical trials of transcranial direct current stimulation: participant and assessor blinding is inadequate at intensities of 2mA.

2012 ◽  
Author(s):  
Keith Muir
Keyword(s):  
Clinical Trials ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Direct Current Stimulation

Reducing Transcranial Direct Current Stimulation-Induced Erythema With Skin Pretreatment: Considerations for Sham-Controlled Clinical Trials

2014 ◽  
Vol 18 (4) ◽  
pp. 261-265 ◽  
Author(s):  
Fabiana Guarienti ◽  
Wolnei Caumo ◽  
Pedro Shiozawa ◽  
Quirino Cordeiro ◽  
Paulo S. Boggio ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Controlled Clinical Trials ◽  
Direct Current Stimulation

Evaluation of Sham Transcranial Direct Current Stimulation for Randomized, Placebo-Controlled Clinical Trials

2013 ◽  
Vol 6 (4) ◽  
pp. 690-695 ◽  
Author(s):  
Ulrich Palm ◽  
Eva Reisinger ◽  
Daniel Keeser ◽  
Min-Fang Kuo ◽  
Oliver Pogarell ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Controlled Clinical Trials ◽  
Direct Current Stimulation

Proceedings #12. Remotely-supervised Transcranial Direct Current Stimulation (RS-tDCS) for Parkinson’s Disease (PD) Clinical Trials: Guidelines and Feasibility

2017 ◽  
Vol 10 (4) ◽  
pp. e59-e60 ◽  
Author(s):  
Natalie Pawlak ◽  
Shashank Agarwal ◽  
Milton Biagioni ◽  
Marom Bikson ◽  
Abhishek Datta ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Trials ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Direct Current Stimulation

scholarly journals Rethinking Clinical Trials of Transcranial Direct Current Stimulation: Participant and Assessor Blinding Is Inadequate at Intensities of 2mA

PLoS ONE ◽  
2012 ◽  
Vol 7 (10) ◽  
pp. e47514 ◽  
Author(s):  
Neil E. O’Connell ◽  
John Cossar ◽  
Louise Marston ◽  
Benedict M. Wand ◽  
David Bunce ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Direct Current Stimulation

scholarly journals Transcranial direct current stimulation for auditory verbal hallucinations: a systematic review of clinical trials

2021 ◽  
Vol 16 (4) ◽  
pp. 666
Author(s):  
Youguo Hao ◽  
Ali Yadollahpour ◽  
Samaneh Rashidi ◽  
Myles Jones ◽  
Eric Murillo-Rodriguez ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Auditory Verbal Hallucinations ◽  
Direct Current Stimulation

scholarly journals Advances in the Use of Neuromodulation for Neurogenic Dysphagia: Mechanisms and Therapeutic Application of Pharyngeal Electrical Stimulation, Transcranial Magnetic Stimulation, and Transcranial Direct Current Stimulation

2020 ◽  
Vol 29 (2S) ◽  
pp. 1044-1064 ◽  
Author(s):  
Ayodele Sasegbon ◽  
Ivy Cheng ◽  
Mengqing Zhang ◽  
Shaheen Hamdy
Keyword(s):  
Clinical Trials ◽  
Electrical Stimulation ◽  
Transcranial Magnetic Stimulation ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Magnetic Stimulation ◽  
Motor System ◽  
Neurogenic Dysphagia ◽  
Therapeutic Application ◽  
Direct Current Stimulation

Purpose The swallowing motor system and, specifically, its cortical substrates appear to have certain unique properties that make it highly susceptible to brain plasticity, both driven and following injury. Furthermore, neurogenic dysphagia is a common complication of brain disease, associated with poor outcomes, and yet treatment options remain limited. Therefore, translating the physiology of neurostimulation into clinical populations becomes imperative. In this review, we describe therapeutic application of neuroplasticity in the human swallowing motor system by initially examining the role of pharyngeal electrical stimulation from a mechanistic perspective and then reporting on clinical studies using this approach. Thereafter, we explore the application of noninvasive brain stimulation, which has previously been used to treat nervous system disorders such as depression, pain modulation, and cognitive impairment. Transcranial brain stimulations, in particular, transcranial magnetic stimulation and transcranial direct current stimulation, have been utilized by a number of investigators for rehabilitation in early-stage clinical trials, including dysphagia after neurological disease. In this review, we assess its usefulness in neurogenic dysphagia. Conclusion Early studies indicate these emerging neurostimulatory techniques hold future therapeutic promise. However, both a greater number of and larger clinical trials are required to provide evidence delineating their efficacy and scope of application.

scholarly journals Transcranial direct current stimulation for the treatment of tinnitus: a review of clinical trials and mechanisms of action

2018 ◽  
Vol 19 (1) ◽  
Author(s):  
Tifei Yuan ◽  
Ali Yadollahpour ◽  
Julio Salgado-Ramírez ◽  
Daniel Robles-Camarillo ◽  
Rocío Ortega-Palacios
Keyword(s):  
Clinical Trials ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Mechanisms Of Action ◽  
Direct Current Stimulation

Electroencephalographic analysis of brain activity after interventions with transcranial direct current stimulation over the motor cortex: a systematic review

2020 ◽  
pp. 105971232093075
Author(s):  
Jamile Benite Palma Lopes ◽  
Isabela Marques Miziara ◽  
Danial Kahani ◽  
Lorraine Barbosa Cordeiro ◽  
Paulo Roberto Fonseca Junior ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Brain Activity ◽  
Direct Current Stimulation ◽  
Brain Signals ◽  
Mesh Terms ◽  
Before And After ◽  
Adequate Quality

This study aims to determine processes and procedures for the analysis of the behavior of brain signals in clinical trials before and after different intervention protocols involving transcranial direct current stimulation (tDCS). In this study, PubMed and Cochrane databases were searched for original articles describing clinical trials that used electroencephalography to analyze the behavior of brain signals after submitted to transcranial direct current stimulation. Searches were conducted with MeSH terms for clinical trials to determine the behavior of brain activity over time through evaluations performed before and after a period of intervention involving tDCS. The search was limited to articles published in English in the last ten years. It was found 257 articles during the initial search, where 14 of which were submitted to an appraisal of methodological quality, and 4 were considered to have adequate quality. Based on the results, there is inconsistency in the processes and procedures used for the acquisition of brain signals, even when limiting the search to clinical trials offering an analysis of evaluations performed before and after clinical interventions. Moreover, researchers seek to offer guidance regarding the acquisition of electroencephalography (EEG) signals to favor the quality of the data but fail to standardize regions for these acquisitions in the analysis of the results of tDCS.

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