Faculty Opinions recommendation of Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias.

2016 ◽  
Author(s):  
Jan Starý ◽  
Michaela Kotrová
Keyword(s):  
Therapeutic Approach ◽  
Hsp90 Inhibition

scholarly journals Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias

Blood ◽  
2015 ◽  
Vol 126 (22) ◽  
pp. 2479-2483 ◽  
Author(s):  
Nicole Kucine ◽  
Sachie Marubayashi ◽  
Neha Bhagwat ◽  
Efthymia Papalexi ◽  
Priya Koppikar ◽  
...  
Keyword(s):  
Mouse Models ◽  
Therapeutic Efficacy ◽  
Therapeutic Approach ◽  
Hsp90 Inhibition ◽  
Key Points

Key Points PU-H71, a novel purine scaffold inhibitor, shows potent therapeutic efficacy in JAK-mutant ALL cells and mouse models. HSP90 inhibition retains therapeutic efficacy in ruxolitinib-persistent JAK-mutant ALL cells.

From inflammation to depression - St Johns wort as a therapeutic approach

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
O Kelber ◽  
J Müller ◽  
SN Okpanyi ◽  
K Nieber ◽  
C Kolb
Keyword(s):  
Therapeutic Approach

Advanced inoperable type B3 thymoma: Monitoring of a novel therapeutic approach with radio-chemo therapy and sorafenib by FDG-PET and CT

2010 ◽  
Vol 49 (05) ◽  
pp. N41-N43
Author(s):  
T. Winder ◽  
A. Schuster ◽  
A. Becherer ◽  
K. Gasser ◽  
A. De Vries ◽  
...  
Keyword(s):  
Fdg Pet ◽  
Therapeutic Approach ◽  
Novel Therapeutic
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