Faculty Opinions recommendation of Subcutaneous ivermectin use in the treatment of severe Strongyloides stercoralis infection: two case reports and a discussion of the literature.

Author(s):  
Pedro Legua Leiva
Pathogens ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 439
Author(s):  
Letizia Ottino ◽  
Dora Buonfrate ◽  
Paola Paradies ◽  
Zeno Bisoffi ◽  
Alberto Antonelli ◽  
...  

Autochthonous human and canine strongyloidiasis is reported in Europe but is unclear whether the transmission of infection still occurs. We report a previously unpublished human case in an Italian teen and perform a systematic review of literature on autochthonous human and canine strongyloidiasis in Europe to investigate the current dynamic of transmission. Overall, 109 papers published after 1987 were included and one previously unpublished Italian case was added. Eighty case reports were retrieved and 42 of them (52.5%) had severe strongyloidiasis. Most cases were diagnosed in Spain, Italy and France. The median age was 58, the most represented age group was 61–70 years, 11 patients were under 30, and 7 of them were diagnosed after 2000. Epidemiological studies on human strongyloidiasis showed prevalence ranging from 0.56% to 28%. Overall, agriculture work, mine work and walking barefoot were the most commonly reported risk factors for infection. Canine strongyloidiasis was reported mainly in Italy (68 cases), but a few cases occurred also in Iceland, Finland, England, Germany, France, Switzerland, Russia, Slovakia, Romania and Greece. Autochthonous strongyloidiasis is still reported in Europe and sporadic transmission still occurs. Health care professionals should be aware of this issue to identify infected subjects and avoid adverse outcomes, especially in immunosuppressed patients. Further investigations are needed to clarify the zoonotic transmission of this nematode.


2011 ◽  
Vol 45 (12) ◽  
pp. 10
Author(s):  
SHERRY BOSCHERT
Keyword(s):  

VASA ◽  
2018 ◽  
Vol 47 (4) ◽  
pp. 273-277
Author(s):  
Christopher Lowe ◽  
Oussama El Bakbachi ◽  
Damian Kelleher ◽  
Imran Asghar ◽  
Francesco Torella ◽  
...  

Abstract. The aim of this review was to investigate presentation, aetiology, management, and outcomes of bowel ischaemia following EVAR. We present a case report and searched electronic bibliographic databases to identify published reports of bowel ischaemia following elective infra-renal EVAR not involving hypogastric artery coverage or iliac branch devices. We conducted our review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement standards. In total, five cohort studies and three case reports were included. These studies detailed some 6,184 infra-renal elective EVARs, without procedure-related occlusion of the hypogastric arteries, performed between 1996 and 2014. Bowel ischaemia in this setting is uncommon with an incidence ranging from 0.5 to 2.8 % and includes a spectrum of severity from mucosal to transmural ischaemia. Due to varying reporting standards, an overall proportion of patients requiring bowel resection could not be ascertained. In the larger series, mortality ranged from 35 to 80 %. Atheroembolization, hypotension, and inferior mesenteric artery occlusion were reported as potential causative factors. Elderly patients and those undergoing prolonged procedures appear at higher risk. Bowel ischaemia is a rare but potentially devastating complication following elective infra-renal EVAR and can occur in the setting of patent mesenteric vessels and hypogastric arteries. Mortality ranges from 35 to 80 %. Further research is required to identify risk factors and establish prophylactic measures in patients that have an increased risk of developing bowel ischaemia after standard infra-renal EVAR.


VASA ◽  
2010 ◽  
Vol 39 (1) ◽  
pp. 43-53 ◽  
Author(s):  
Grotenhermen

Background: To investigate the hypothesis that cases of arteritis similar to thromboangiitis obliterans (TAO) and associated with the use of cannabis were caused by cannabis or THC (dronabinol), or that cannabis use is a co-factor of TAO. Patients and methods: A systematic review on case reports and the literature on so-called cannabis arteritis, TAO, and cardiovascular effects of cannabinoids was conducted. Results: Fifteen reports with 57 cases of an arteritis associated with the use of cannabis and two additional case series of TAO, in which some patients also used cannabis, were identified. Clinical and pathological features of cannabis-associated arteritis do not differ from TAO and the major risk factor of TAO, tobacco use, was present in most, if not in all of these cases. The proposed pathophysiological mechanisms for the development of an arteritis by cannabis use are not substantiated. Conclusions: The hypothesis of cannabis being a causative factor or co-factor of TAO or an arteritis similar to TAO is not supported by the available evidence. The use of the term “cannabis arteritis” should be avoided until or unless more convincing scientific support is forthcoming.


Swiss Surgery ◽  
1999 ◽  
Vol 5 (6) ◽  
pp. 281-287 ◽  
Author(s):  
Schindele ◽  
Hackenbruch ◽  
Sutter ◽  
Schärer ◽  
Leutenegger

Häufige Frakturen im Bereich der Schulter betreffen je nach Alter die Clavicula oder den proximalen Humerus. Die Indikation zur operativen Stabilisierung ist bei Luxationsfrakturen des lateralen Claviculaendes und bei instabilen und dislozierten Frakturen des proximalen Humerus grosszügig zu stellen. Werden Kirschner-Drähte zur Osteosynthese eingesetzt muss in hohem Masse mit Drahtwanderungen oder Drahtbrüchen gerechnet werden. In mehreren Fällen wird in der Literatur auf diese Komplikation hingewiesen. Anhand von vier Fallbeispielen möchten wir Ursachen und technische Voraussetzungen aufzeigen, die bei dieser operativen Variante zu lebensbedrohlichen Komplikationen durch eine sekundäre Migration führen können. Dies unter Umständen nach Jahren und ohne klinische Symptome. Die Indikation zur Kirschnerdraht-Osteosynthese muss vor allem bei vorliegender Osteoporose zurückhaltend gestellt werden. Regelmässige Kontrollen in der postoperativen Phase werden empfohlen, die Entfernung der Drähte sollte bei konsolidierter Fraktur frühzeitig geplant werden.


2007 ◽  
Author(s):  
Z. Pires ◽  
M. Lobo ◽  
S. Mendes ◽  
S. Fernandes
Keyword(s):  

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