Faculty Opinions recommendation of Clinical diagnosis of Alzheimer's disease: recommendations of the International Working Group.

Author(s):  
Daniela Perani
Author(s):  
Bruno Dubois ◽  
Nicolas Villain ◽  
Giovanni B Frisoni ◽  
Gil D Rabinovici ◽  
Marwan Sabbagh ◽  
...  

2021 ◽  
Vol 4 (2) ◽  
Author(s):  
Ishaan Ishaan Bharadwaj ◽  
◽  

Alzheimer’s is a progressive neurodegenerative disease that usually starts slowly and gradually worsens over time. It constitutes for over 65% of dementia cases and currently has no cure. This paper reviews the biomarkers for Alzheimer’s Disease (AD) and evaluates these biomarkers based on various pathologies they are associated with, using the International Working Group (IWG) criteria, sensitivity, specificity etc. This paper summarizes the existing biomarkers, critically compares them and highlights which biomarkers are most effective for clinical diagnosis. It also discusses some of the drawbacks associated with using some biomarkers, either alone or in combination with others


2021 ◽  
Vol 17 (S5) ◽  
Author(s):  
Nicolas Villain ◽  
Bruno Dubois ◽  
Giovanni B. Frisoni ◽  
Gil D. Rabinovici ◽  
Marwan Noel Sabbagh ◽  
...  

2021 ◽  
Vol 17 (S5) ◽  
Author(s):  
Bruno Dubois ◽  
Nicolas Villain ◽  
Giovanni Frisoni ◽  
Gil D. Rabinovici ◽  
Marwan Noel Sabbagh ◽  
...  

2019 ◽  
Vol 30 (3) ◽  
pp. 157-168
Author(s):  
Helmut Hildebrandt ◽  
Jana Schill ◽  
Jana Bördgen ◽  
Andreas Kastrup ◽  
Paul Eling

Abstract. This article explores the possibility of differentiating between patients suffering from Alzheimer’s disease (AD) and patients with other kinds of dementia by focusing on false alarms (FAs) on a picture recognition task (PRT). In Study 1, we compared AD and non-AD patients on the PRT and found that FAs discriminate well between these groups. Study 2 served to improve the discriminatory power of the FA score on the picture recognition task by adding associated pairs. Here, too, the FA score differentiated well between AD and non-AD patients, though the discriminatory power did not improve. The findings suggest that AD patients show a liberal response bias. Taken together, these studies suggest that FAs in picture recognition are of major importance for the clinical diagnosis of AD.


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