Faculty Opinions recommendation of Involvement of RIG-I Pathway in Neurotropic Virus-Induced Acute Flaccid Paralysis and Subsequent Spinal Motor Neuron Death.

2021 ◽  
Author(s):  
Arup Banerjee
Keyword(s):  
Motor Neuron ◽  
Acute Flaccid Paralysis ◽  
Flaccid Paralysis ◽  
Neuron Death ◽  
Spinal Motor Neuron ◽  
Neurotropic Virus ◽  
Spinal Motor ◽  
Motor Neuron Death

scholarly journals Involvement of RIG-I Pathway in Neurotropic Virus-Induced Acute Flaccid Paralysis and Subsequent Spinal Motor Neuron Death

mBio ◽  
2021 ◽  
Author(s):  
Meenakshi Bhaskar ◽  
Sriparna Mukherjee ◽  
Anirban Basu
Keyword(s):  
Molecular Mechanisms ◽  
Viral Infections ◽  
Clinical Manifestations ◽  
Neuron Death ◽  
Spinal Motor Neuron ◽  
Spinal Motor ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Delayed Neuropsychiatric Sequelae ◽  
Motor Neuron Death

Neurotropic viral infections are an increasingly common cause of immediate or delayed neuropsychiatric sequelae, cognitive impairment, and movement disorders or, in severe cases, death. Given the highest reported disability-adjusted life years and mortality rate worldwide, a better understanding of molecular mechanisms for underlying clinical manifestations like AFP will help in development of more effective tools for therapeutic solutions.

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