Terapia larval no tratamento de feridas / Larval therapy in wound treatment

Operated patients suffering from diabetes are at risk of developing postoperative complications. Modern technologies of postoperative wound treatment and modern dressings allow to avoid complications and speed up the process of postoperative wound healing.

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Three-dimensionally (3D) printing of propolis incorporated sodium alginate scaffolds for wound treatment

Authorea ◽

10.22541/au.158757087.73061699 ◽

2020 ◽

Author(s):

Muhammet UZUN ◽

Cem ST NDA

Keyword(s):

3D Printing ◽

Sodium Alginate ◽

Wound Treatment

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Evaluation of Larval Therapy Compared to Antibiotic Therapy in the Treatment of Skin Wounds in Rabbits

Journal of Medical Entomology ◽

10.1093/jme/tjaa229 ◽

2020 ◽

Author(s):

Luciano Antunes Barros ◽

Lucas Xavier Sant’Anna ◽

Claudia Soares Lessa ◽

Valéria Magalhães Aguiar Coelho ◽

Mariana dos Passos Nunes ◽

...

Keyword(s):

Antibiotic Therapy ◽

Bacterial Infection ◽

Therapy Group ◽

Multidrug Resistant ◽

Therapeutic Modality ◽

Infection Group ◽

Cutaneous Wounds ◽

Group 2 ◽

Treatment Of Wounds ◽

Larval Therapy

Abstract Larval therapy (LT) is a therapeutic modality that uses larvae of necrophagous flies for the treatment of wounds. The use of this therapy presents several benefits, due to the action of the larvae that remove necrotic tissue selectively, exercising antimicrobial action, and promoting healing. There are situations in which LT proves to be the only or the best alternative for the patient, such as wounds infected by multidrug-resistant microorganisms or when treatment difficulties may lead to an indication for amputation. The purpose of this study was to compare the efficiency of LT, using larvae of Chrysomya megacephala, with that of antibiotic therapy in the treatment of cutaneous wounds infected with Pseudomonas aeruginosa. Twenty-four rabbits were used to perform the experiment, distributed in four groups: group 1, induced wound without bacterial infection; group 2, induced wound with bacterial infection; group 3, induced wound with bacterial infection and antibiotic therapy; group 4, induced wound with bacterial infection and LT. The macroscopic, microscopic, and statistical analyses indicated that LT was as effective as antibiotic therapy in wound healing.

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Preparation of nano-hydroxyapatite/chitosan/tilapia skin peptides hydrogels and its burn wound treatment

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2021.03.085 ◽

2021 ◽

Author(s):

Ouyang Qianqian ◽

Kong Songzhi ◽

Huang Yongmei ◽

Ju Xianghong ◽

Li Sidong ◽

...

Keyword(s):

Wound Treatment ◽

Burn Wound

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What is the effect of larval therapy on the debridement of venous leg ulcers? A systematic review

Journal of Tissue Viability ◽

10.1016/j.jtv.2021.05.005 ◽

2021 ◽

Author(s):

Elaine Greene ◽

Pinar Avsar ◽

Zena Moore ◽

Linda Nugent ◽

Tom O’Connor ◽

...

Keyword(s):

Systematic Review ◽

Leg Ulcers ◽

Venous Leg Ulcers ◽

Larval Therapy

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Successful surgical closure of infected abdominal wounds following preconditioning with negative pressure wound therapy

Langenbeck s Archives of Surgery ◽

10.1007/s00423-021-02221-w ◽

2021 ◽

Author(s):

Johanna C. Wagner ◽

Anja Wetz ◽

Armin Wiegering ◽

Johan F. Lock ◽

Stefan Löb ◽

...

Keyword(s):

Negative Pressure ◽

Wound Closure ◽

Negative Pressure Wound Therapy ◽

Wound Complications ◽

Skin Closure ◽

Wound Treatment ◽

Open Wound ◽

Wound Therapy ◽

Significant Difference ◽

Open Wound Treatment

Abstract Purpose Traditionally, previous wound infection was considered a contraindication to secondary skin closure; however, several case reports describe successful secondary wound closure of wounds “preconditioned” with negative pressure wound therapy (NPWT). Although this has been increasingly applied in daily practice, a systematic analysis of its feasibility has not been published thus far. The aim of this study was to evaluate secondary skin closure in previously infected abdominal wounds following treatment with NPWT. Methods Single-center retrospective analysis of patients with infected abdominal wounds treated with NPWT followed by either secondary skin closure referenced to a group receiving open wound therapy. Endpoints were wound closure rate, wound complications (such as recurrent infection or hernia), and perioperative data (such as duration of NPWT or hospitalization parameters). Results One hundred ninety-eight patients during 2013–2016 received a secondary skin closure after NPWT and were analyzed and referenced to 67 patients in the same period with open wound treatment after NPWT. No significant difference in BMI, chronic immunosuppressive medication, or tobacco use was found between both groups. The mean duration of hospital stay was 30 days with a comparable duration in both patient groups (29 versus 33 days, p = 0.35). Interestingly, only 7.7% of patients after secondary skin closure developed recurrent surgical site infection and in over 80% of patients were discharged with closed wounds requiring only minimal outpatient wound care. Conclusion Surgical skin closure following NPWT of infected abdominal wounds is a good and safe alternative to open wound treatment. It prevents lengthy outpatient wound therapy and is expected to result in a higher quality of life for patients and reduce health care costs.

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