scholarly journals Classificação do papillomavirus humano segundo um Banco Internacional de Padronização (2021) / Classification of human papillomaviruses according to an international Standardization Bank (2021)

2021 ◽  
Vol 7 (9) ◽  
pp. 88475-88487
Author(s):  
José de Ribamar Ross ◽  
Irene Sousa Da Silva ◽  
Joseane da costa Ximenes Rocha ◽  
Galbia Nelma Silva Rodrigues Santos ◽  
Fabiano Rossi Soares Ribeiro ◽  
...  
2019 ◽  
pp. 331-349
Author(s):  
A. Poltavskyi

The article is devoted to one of the most frequently faced crime investigation procedure – scene examination (investigation), during which an investigator and a specialist to recognize, record, collect, transport and store trace information before conducting expert examination. Their activity, in this case, consists of a number of main stages: the recognition of traces on the subjects, which at the time of the commission of crimes could have formed traces and which (subjects with traces) can be collected; the recognition of traces on the subjects, which cannot be collected; recording, collecting, packing of traces on the subjects and traces; transportation of collected subjects with traces and traces to the pre-trial investigation authorities, its storage until sending them to the institution of forensic examinations; samples’ obtaining for comparative examination; transportation of subjects with traces and traces and samples for expert research. These main stages constitute the technology of scene examination (investigation), which (technology), in the general context, is defined as a set of knowledge, information about the sequence of separate work operations in the production process of something. The analysis of the integration of the concept of “technology” in forensic science and forensic expertology showed that the general understanding of the term “technology” there is no classification of technologies, their structure and content, and the order of representation at a practical level for the implementation into crime investigation. The article illustrates some shortcomings of scene examination (investigation). The analysis of regulations that adjusting scene examination (investigation) shows that they do not have detailed instructions for the implementation of specific actions by specialists. In the opinion of the author, the solution of problematic issues should be the standardization of the institutions’ activities that provide for the conduct of scene examination (investigation) and expert research. The article briefly deals with the history of international standardization, the state of standardization in Ukraine, analyzes the provisions of the international standard ISO 21043-2: 2018 “Recognition, recording, collecting, transport and storage of items” (which have potential forensic significance). According to the results of the research, conclusions were made on the necessity of implementation into the work of the institutions that provide scene examination (investigation) and expert research, quality management systems in accordance with the requirements of ISO/IEC 17020 ISO/IEC 17025, as well as the harmonization of the international standard ISO 21043-2: 2018 as a national regulatory document (National Standards of Ukraine (DSTU)) with the further implementation into practical activities on crime detection. Key words: international standardization, ISO 21043-2:2018, standardization of the technology of scene examination (investigation).


1994 ◽  
Vol 40 (10) ◽  
pp. 1890-1892 ◽  
Author(s):  
G Terry ◽  
L Ho ◽  
A Szarewski ◽  
J Cuzick

Abstract Detection of DNA from human papillomaviruses (HPV) of high and intermediate oncogenic risk in cervical smears may predict the presence of cervical cancer or may indicate precancerous changes. Here we describe a semiautomated polymerase chain reaction system for the detection and classification of HPV DNA that is present in clinically significant amounts in routine cervical scrapes.


1986 ◽  
Vol 17 (6) ◽  
pp. 552-559 ◽  
Author(s):  
Robert J. Brescia ◽  
A. Bennett Jenson ◽  
Wayne D. Lancaster ◽  
Robert J. Kurman

2002 ◽  
Vol 76 (19) ◽  
pp. 9702-9715 ◽  
Author(s):  
Jennifer L. Bromberg-White ◽  
Craig Meyers

ABSTRACT The upstream regulatory region (URR) of various types of human papillomaviruses (HPVs) has been shown to contain functional glucocorticoid response elements (GREs), including HPV type 11 (HPV11), HPV16, and HPV18. Glucocorticoids have been demonstrated to induce the transcriptional activity of the early promoters of these HPV types. Although it has been assumed that the URR of HPV31 contains at least one GRE, no functionality has been demonstrated. We attempt to show here inducibility of the URR of HPV31 by the synthetic glucocorticoid dexamethasone (dex). By sequence analysis we identified three potential GREs in the URR of HPV31. Gel shift analysis indicated that each of these three sites has the potential to be a functional GRE. However, constructs containing the full-length URR, 5′ deletions of the URR, and an internal fragment of the URR containing all three putative GREs were only weakly inducible by dex. Linker scanning mutants, whereby each potential GRE was replaced individually, in double combination, or in triple combination by a unique polylinker, had no effect on dex inducibility. Replacement of each of the three HPV31 GREs with the GRE of HPV18 failed to induce a response to dex. Placement of the HPV18 GRE into the URR of HPV31 in a region similar to its location in the HPV18 URR was also unable to result in a strong dex induction of the HPV31 URR. These data suggest that the lack of dex inducibility is due to the overall context of the HPV31 URR and may be dependent on the requirements of the major early promoter for transcriptional activation. Finally, replacement of the HPV18 GRE with each of the HPV31 GREs in HPV18 only showed weak inducibility, indicating that the three GREs of HPV31 are in fact only weak inducers of dex. Overall, these data suggest that dex responsiveness, along with oncogenic potential, may provide a possible explanation for the classification of HPV31 as an intermediate-risk virus and demonstrate the complexity of transcriptional regulation of the URR of HPV.


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