scholarly journals Topical Gel of Vitamin A Solid Lipid Nanoparticles: A Hopeful Promise as a Dermal Delivery System

2020 ◽  
Author(s):  
Mahshid Boskabadi ◽  
Majid Saeedi ◽  
Jafar Akbari ◽  
Katayoun Morteza-Semnani ◽  
Seyyed Mohammad Hassan Hashemi ◽  
...  
Keyword(s):  
Vitamin A ◽  
Delivery System ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Topical Gel ◽  
Solid Lipid ◽  
Dermal Delivery

scholarly journals Topical gel of Metformin solid lipid nanoparticles: A hopeful promise as a dermal delivery system

2019 ◽  
Vol 175 ◽  
pp. 150-157 ◽  
Author(s):  
Seyyed Sohrab Rostamkalaei ◽  
Jafar Akbari ◽  
Majid Saeedi ◽  
Katayoun Morteza-Semnani ◽  
Ali Nokhodchi
Keyword(s):  
Delivery System ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Topical Gel ◽  
Solid Lipid ◽  
Dermal Delivery

scholarly journals Positive-charged solid lipid nanoparticles as paclitaxel drug delivery system in glioblastoma treatment

2014 ◽  
Vol 88 (3) ◽  
pp. 746-758 ◽  
Author(s):  
Daniela Chirio ◽  
Marina Gallarate ◽  
Elena Peira ◽  
Luigi Battaglia ◽  
Elisabetta Muntoni ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Solid Lipid

Solid lipid nanoparticles incorporated in dextran hydrogels: A new drug delivery system for oral formulations

2006 ◽  
Vol 325 (1-2) ◽  
pp. 140-146 ◽  
Author(s):  
Maria Antonietta Casadei ◽  
Felice Cerreto ◽  
Stefania Cesa ◽  
Maria Giannuzzo ◽  
Michelle Feeney ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Solid Lipid ◽  
New Drug ◽  
Oral Formulations

Vitamin A-loaded solid lipid nanoparticles for topical use: drug release properties

2000 ◽  
Vol 66 (2-3) ◽  
pp. 115-126 ◽  
Author(s):  
V. Jenning ◽  
M. Schäfer-Korting ◽  
S. Gohla
Keyword(s):  
Drug Release ◽  
Vitamin A ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Solid Lipid

Development of Mupirocin- Tinidazole solid- Lipid Nanoparticles Loaded Topical gel for the Management of Bacterial Wound Infections

2021 ◽  
pp. 2785-2790
Author(s):  
Veintramuthusankar Veintramuthusankar ◽  
Pushparajudayakumar Pushparajudayakumar ◽  
Rajanduraibabyroselin Rajanduraibabyroselin
Keyword(s):  
Particle Size ◽  
Drug Release ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Fickian Diffusion ◽  
Standard Drug ◽  
Topical Gel ◽  
Solid Lipid ◽  
Homogenization Technique ◽  
Significant Difference

Solid lipid nanoparticles (SLNs) are novel drug carrier system which consists of a solid matrix composed of a lipid being solid at both room and body temperatures with a mean Particle Size (PS) between 50 and 1000 nm Mupirocin -Tinidazole solid-lipid nanoparticles were prepared using hot homogenization technique using Glyceryl monosterate, Stearic acid, Tween 80 and Poloxamer 188 using hot homogenization technique. Size of the nanoparticles was in the range of 83 to 211 nm with the zeta potential values between -2.1 to -5.2. Atomic Force Microscopy (AFM) confirms the spherical shape of solid lipid nanoparticles. Entrapment efficiency was best in the F1 formulation. In vitro release of the pure drug was found to be 75% of mupirocin and 66.5% of tinidazole at the end of 1 hr. Drug release from SLNs dispersion followed Korsermeyrs peppas-model, indicating fickian diffusion drug release, while that from the gel followed non Fickian model drug release. Antibacterial activity of the SLNs was less but the SLNs based gel shows no significant difference in activity to that of standard drug gentamycin against aerobic bacteria. The SLNs dispersion exhibited physicochemical stability under refrigeration upto 45 days without significant difference in particle size. Best formulation was developed into a topical gel using sodium alginate and it was evaluated for pH, viscosity, spreadbility, extrudability, bloom strength, Minimum Inhibitory Concentration (MIC) and Methicillin resistant staphylococcus aureus (MRSA). Extrudability and spreadability parameters of the gel are similar to that of marketed Mupirocin 2% cream formulation

Preparation, characterization, and evaluation of gatifloxacin loaded solid lipid nanoparticles as colloidal ocular drug delivery system

2009 ◽  
Vol 18 (3) ◽  
pp. 191-204 ◽  
Author(s):  
Mohd. Abul Kalam ◽  
Yasmin Sultana ◽  
Asgar Ali ◽  
Mohd. Aqil ◽  
Anil K. Mishra ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Ocular Drug Delivery ◽  
Solid Lipid
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