scholarly journals Dupuytrens disease–where to from here?

2019 ◽  
Vol 2 (1) ◽  
pp. 3-4
Author(s):  
David McCombe
Keyword(s):  
Plastic Surgery ◽  
Hand Surgery ◽  
Therapeutic Benefit ◽  
Dupuytren’S Contracture ◽  
Dupuytren's Disease ◽  
Dupuytren's Contracture ◽  
Collagenase Injection ◽  
Significant Step ◽  
The Subject ◽  
Results Of Surgery

The advent of fasciotomy by intralesional collagenase injection has been a significant step forward in the treatment of Dupuytren’s contracture. While the therapeutic benefit of collagenase injection in the treatment of Dupuytren’s contracture has been established, seeking its value relative to the surgery has stimulated an interesting debate about the management of the condition, causing us to examine the results of surgery in more detail. Dupuytren’s disease and its treatment has become topical and will be the subject of the hand surgery symposium at this year’s Plastic Surgery Congress from 30 May – 1 June 2019 at the Melbourne Convention and Exhibition Centre, Victoria, Australia.

scholarly journals Dupuytren’s Contracture with Secondary Ulnar Neuropathy

2020 ◽  
Vol 11 (03) ◽  
pp. 481-483
Author(s):  
Chen Fei Ng
Keyword(s):  
Diabetes Mellitus ◽  
Clinical Symptoms ◽  
Chronic Alcoholism ◽  
Ulnar Neuropathy ◽  
Dupuytren’S Disease ◽  
Dupuytren’S Contracture ◽  
Hand Trauma ◽  
Dupuytren's Disease ◽  
Dupuytren's Contracture ◽  
Patients With Diabetes

AbstractDupuytren’s disease is a progressive fibrotic condition of the hand. The underlying pathomechanism is not fully known. Dupuytren’s contracture can be seen in patients with diabetes mellitus, chronic alcoholism, smoking, or hand trauma. It is uncommon to affect the neurovascular supply causing clinical symptoms. We describe a patient with idiopathic Dupuytren’s disease complicated with bilateral ulnar neuropathies and highlight the importance of such rare treatable complication.

scholarly journals Needle Fasciotomy or Collagenase Injection in the Treatment of Dupuytren’s Contracture

2020 ◽  
Vol 8 (1) ◽  
pp. e2606
Author(s):  
Islam Abdelrahman ◽  
Moustafa Elmasry ◽  
Ingrid Steinvall ◽  
Christina Turesson ◽  
Folke Sjöberg ◽  
...  
Keyword(s):  
Dupuytren’S Contracture ◽  
Dupuytren's Contracture ◽  
Collagenase Injection

Day Care Surgery for Advanced Dupuytren’s Contracture

1997 ◽  
Vol 22 (2) ◽  
pp. 191-192 ◽  
Author(s):  
L. B. EBSKOV ◽  
M. E. H. BOECKSTYNS ◽  
A. I. SØRENSEN ◽  
M. HAUGEGAARD
Keyword(s):  
Day Care ◽  
Reflex Sympathetic Dystrophy ◽  
Hand Surgery ◽  
Dupuytren’S Contracture ◽  
Complication Rates ◽  
Dupuytren's Contracture ◽  
Day Care Surgery ◽  
Care Surgery ◽  
Selection Of Patients ◽  
Selection Of

Seventy-six consecutive patients suffering from advanced Dupuytren’s contracture were analysed in order to evaluate the safety of day care surgery. The complication rates for haematoma, necrosis, infection and reflex sympathetic dystrophy were acceptable, but we found an unacceptably high percentage of nerve lesions. Day care treatment was achieved in all but seven cases. We concluded that advanced Dupuytren’s contracture can be treated by day care surgery but the operations should be performed by surgeons who are skilled in hand surgery, and individual selection of patients with recurrence seems advisable.

An Investigation into the Role of Inflammatory Cells in Dupuytren’s Disease

1991 ◽  
Vol 16 (3) ◽  
pp. 267-271 ◽  
Author(s):  
J. G. ANDREW ◽  
S. M. ANDREW ◽  
A. ASH ◽  
B. TURNER
Keyword(s):  
Inflammatory Cells ◽  
Dupuytren’S Disease ◽  
Dupuytren’S Contracture ◽  
Palmar Fascia ◽  
Dupuytren's Disease ◽  
Dupuytren's Contracture ◽  
Microvascular Changes ◽  
Macrophage Marker ◽  
Fibrotic Diseases

An immunohistochemical study was performed on nodules excised from the palmar fascia of patients with Dupuytren’s contracture. In cellular nodules, antibodies to actin (used as a marker for myofibroblasts), desmin, vimentin, Mac 387 (a macrophage marker) and leucocyte common antigen were used. A correlation was demonstrated between the numbers of macrophages and the presence of myofibroblasts. The presence of myofibroblasts is generally considered to indicate the active stage of the disease. Inflammatory cells other than macrophages were largely absent from the nodules, although lymphocytes were frequent in the tissue around the nodules. Microvascular changes were prominent in the nodules and pericyte proliferation was observed around occluded capillaries. Release of growth factors from macrophages may be important in Dupuytren’s contracture, as is the case in other fibrotic diseases. The possible role of macrophages in the aetiology of Dupuytren’s disease is discussed.

Collagenase Injection for Severe Pipj Induced Dupuytren's Contracture Augmented By a Novel Orthotic Intervention and Therapy Protocol

2012 ◽  
Vol 25 (4) ◽  
pp. e11
Author(s):  
Terri Skirven ◽  
Lauren DeTullio ◽  
Marianne Dunphy ◽  
Abdo Bachoura ◽  
Sidney M. Jacoby ◽  
...  
Keyword(s):  
Dupuytren’S Contracture ◽  
Dupuytren's Contracture ◽  
Collagenase Injection ◽  
Therapy Protocol

Boutonniere Deformity in Dupuytren’s Disease

1988 ◽  
Vol 13 (4) ◽  
pp. 379-382
Author(s):  
J. N. KUHLMANN ◽  
A. BOABIGHI ◽  
S. GUERO ◽  
M. MIMOUN ◽  
S. BAUX
Keyword(s):  
Dupuytren’S Disease ◽  
Dupuytren’S Contracture ◽  
Dupuytren's Disease ◽  
Dupuytren's Contracture ◽  
Complete Ablation ◽  
Boutonniere Deformity ◽  
Extensor Apparatus ◽  
Boutonnière Deformity

The boutonnière deformity in Dupuytren’s disease has been found to be due to fibrous contraction of the transverse retinacular ligament which anteriorly displaces the fibres of the extensor apparatus. Complete ablation of this ligament and liberation of the extensor apparatus arrows easy extension of the finger when operating on severe cases of Dupuytren’s contracture.

scholarly journals “The Serpentine Zone”: A Surgeon's Guide to the Surface Anatomy of the Digital Neurovascular Spiral in Dupuytren's Contracture

2017 ◽  
Vol 10 (01) ◽  
pp. 054-056
Author(s):  
Alistair Macey ◽  
Roshin Thomas
Keyword(s):  
Neurovascular Bundle ◽  
Dupuytren’S Disease ◽  
Dupuytren’S Contracture ◽  
Dupuytren's Disease ◽  
Dupuytren's Contracture ◽  
Surface Anatomy ◽  
Neurovascular Injury

AbstractThe anatomy of the cords that form in Dupuytren's disease is complicated and a spiral cord is the most challenging variant to address. It displaces the neurovascular bundle toward or beyond the midline and closer to the skin. This article illustrates the surface anatomy of the neurovascular spiral to help surgeons identify this zone of danger that the authors term “the serpentine zone.” Careful dissection in this zone will help avoid iatrogenic digital neurovascular injury.

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