scholarly journals Central retinal vein occlusion as the initial presentation of isolated optic nerve sheath metastasis from breast cancer

2021 ◽  
Vol 3 (2) ◽  
pp. 113-119
Author(s):  
Joan Marie Palikat ◽  
Mimiwati Zahari ◽  
Eric Chung ◽  
Aliff Irwan Cheong ◽  
Norlina Ramli
Keyword(s):  
Breast Cancer ◽  
Optic Nerve ◽  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Vision Loss ◽  
Hand Movement ◽  
Vein Occlusion ◽  
Threatening Condition ◽  
Life Threatening ◽  
Central Retinal Vein

Background: Isolated metastasis to the optic nerve (ON) and its sheath from breast cancer (BC) without involvement of other ocular structures is extremely rare. However, it is a pivotal diagnosis to rule out as it is a both sight- and life-threatening condition. We report a case of isolated ON sheath metastasis from BC presenting with central retinal vein occlusion (CRVO). Case presentation: A 47-year-old woman with known metastatic BC presented with painless, progressive vision loss in the left eye. Visual acuity was hand movement with ipsilateral relative afferent pupillary defect. Fundal features suggested CRVO. Atypical rapid resolution of these features led to suspect ON metastasis. Magnetic resonance of the brain showed perineural enhancement of the optic nerves. Vision improved with radiotherapy. Conclusion: Isolated ON sheath metastasis from BC is rare and may present with CRVO. High degree of suspicion is warranted in patients with metastatic disease and atypical findings.

scholarly journals Central Retinal Vein Occlusion in a Childhood Optic Nerve Tumour

2016 ◽  
Vol 40 (1) ◽  
pp. 35-39 ◽  
Author(s):  
Igor Kozak ◽  
Sahar M. Elkhamary ◽  
Thomas M. Bosley
Keyword(s):  
Optic Nerve ◽  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Vein Occlusion ◽  
Nerve Tumour ◽  
Central Retinal Vein

scholarly journals Frosted Branch Angiitis Secondary to Familial Mediterranean Fever Resembling Central Retinal Vein Occlusion

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Serdar Ozates ◽  
Pınar Çakar Ozdal ◽  
Mehmet Yasin Teke
Keyword(s):  
Visual Acuity ◽  
Familial Mediterranean Fever ◽  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Vision Loss ◽  
Retinal Vasculitis ◽  
Frosted Branch Angiitis ◽  
Vein Occlusion ◽  
Mediterranean Fever ◽  
Central Retinal Vein

Purpose. To report a case of unilateral frosted branch angiitis (FBA) resembling central retinal vein occlusion associated with Familial Mediterranean Fever (FMF). Case Report. A 32-year-old woman presented with progressive, painless vision loss in her left eye lasting for 2 days. She was clinically diagnosed with FMF 2 months ago. The best-corrected visual acuity (BCVA) was 20/20 in her right eye and there was light perception in the left. Ophthalmologic examination revealed severe retinal vasculitis showing clinical features of FBA in the left eye. 64 mg/day oral methylprednisolone was started. A significant improvement in retinal vasculitis was observed in two weeks. However, BCVA did not increase significantly due to subhyaloid premacular hemorrhage. Argon laser posterior hyaloidotomy was performed. One week after hyaloidotomy, visual acuity improved to 20/20 and intravitreal hemorrhage disappeared. Four months after the first attack, FBA recurred. Oral methylprednisolone dosage was increased to 64 mg/day and combined with azathioprine 150 mg. At the end of 12-month follow-up, the BCVA was 20/25 and development of epiretinal membrane was observed in the left eye. Conclusions. Frosted branch angiitis may occur with gene abnormalities as an underlying condition. Our case showed that FMF might be a causative disease.

scholarly journals Impending Central Retinal Vein Occlusion

2016 ◽  
Vol 78 (3) ◽  
pp. 20
Author(s):  
Michelle Steenbakkers
Keyword(s):  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Vision Loss ◽  
Clinical Manifestations ◽  
Retinal Vessel ◽  
Retinal Hemorrhages ◽  
Blurred Vision ◽  
Prodromal Phase ◽  
Vein Occlusion ◽  
Central Retinal Vein

Central retinal vein occlusion (CRVO) may present with varied clinical manifestations, ranging from mild blurred vision and scattered retinal hemorrhages to severe vision loss, optic nerve swelling, pronounced retinal hemorrhages, collateral retinal vessel formation and neovascularization. Impending CRVO, also known as partial CRVO, is a relatively poorly-defined sub-classification of the CRVO condition. Those affected are either asymptomatic or may complain of mild, often transient episodes of blurring of vision and present with venous dilation and tortuosity but only a few widely scattered flame-shaped retinal hemorrhages. As an impending CRVO may be the prodromal phase of an acute CRVO, this diagnosis requires careful monitoring of the patient for progression. The following case outlines the differential diagnosis, sequelae and inter-professional management of an impending central retinal venous occlusion.

scholarly journals Aflibercept Treatment and Regimes in Macular Edema Secondary to Central Retinal Vein Occlusion

2019 ◽  
pp. 29-32
Keyword(s):  
Macular Edema ◽  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Vision Loss ◽  
Thrombus Formation ◽  
Treatment Options ◽  
Treatment Modalities ◽  
Multiple Treatment ◽  
Vein Occlusion ◽  
Central Retinal Vein

Central retinal vein occlusion (CRVO) is the most common vascular disease leading cause of vision loss after diabetic retinopathy (DR) and branch retinal vein occlusion (BRVO). The pathogenesis of CRVO involves a thrombus formation leading to increased retinal capillary pressure, increased vascular permeability, and possibly retinal neovascularization. Vision loss due to CRVO is commonly caused by macular edema. Multiple treatment modalities have been used to treat macular edema. Currently, the most common therapy modality used is intravitreal inhibition of vascular endothelial growth factor (VEGF). The three most widely used agents are aflibercept, bevacizumab, and ranibizumab. In addition, intraocular steroids can be used to treat macular edema. This review will briefly cover the treatment options and discuss in greater detail the efficacy and safety of aflibercept.

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