scholarly journals MANIFESTATION OF COVID-19 IN THE FORM OF ACUTE MYOCARDIAL INFARCTION (case report)

2020 ◽  
Vol 7 (4) ◽  
pp. 180-183
Author(s):  
Olga Kadykova ◽  
M. Koshkina
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Differential Diagnosis ◽  
Clinical Picture ◽  
Myocardial Damage ◽  
Cardiovascular Complications ◽  
Objective Data ◽  
Myocardial Mass ◽  
St Segment ◽  
Complicated Course

Acute myocardial infarction is necrosis of any myocardial mass due to ischemia. COVID-19 can be complicated by thrombosis and myocardial damage, which can lead to the deployment of a clinical picture similar to acute myocardial infarction. The material of this article is presented on the example of a clinical case. A woman aged 37 was diagnosed with an acute myocardial infarction, which later turned out to be a manifestation of a complicated course of coronavirus COVID-19 infection. This case drew attention to the absence of a clinical picture specific to this infection in the form of a damage to the respiratory system or intoxication. The case is also distinguished by the presence of a single uncharacteristic clinical manifestation of COVID-19 in the form of a cardiovascular event with elevations of the ST segment on the cardiogram and other objective data and additional research methods characteristic of acute myocardial infarction. The work also analyzed the pathogenetic mechanisms of acute myocardial infarction and cardiovascular complications of COVID-19, examined the general links of pathogenesis of these two pathological units and analyzed the causes of difficulties in their differential diagnosis. In this regard, there are unquestionably complications of differential diagnosis and the prescription of timely correct therapy. A deeper understanding of these data may improve the algorithms for diagnosing acute myocardial infarction and cardiovascular complications of COVID-19.

scholarly journals Cytokine profile in patients with acute myocardial infarction with and without complications

2017 ◽  
Vol 95 (3) ◽  
pp. 233-237
Author(s):  
A. O. Aimagambetova ◽  
L. K. Karazhanova ◽  
A. Kotlyar
Keyword(s):  
Myocardial Infarction ◽  
Cardiovascular Complications ◽  
Cytokine Profile ◽  
Control Group ◽  
Prognostic Role ◽  
Normal Range ◽  
St Segment Elevation ◽  
St Segment ◽  
Complicated Course

The aim of this study was to evaluate the prognostic role of the cytokine profile in patients with ST segment elevation myocardial infarction (STEMI). Materials and methods. In the present paper we studied cytokines IL-6, IL-1β, IL-10, TNFα and CRP in 81 patients with different course of STEMI. Results. In patients with complicated course of STEMI a significant increase in the concentration of IL-6, IL-10, FNOα, CRP was recorded on the 1st, 7th and 14th days compared with control group of healthy subjects and a group of patients with uncomplicated STEMI. Concentrations of TNFα>35.49 pg/ml, IL-6>33.37 pg/ml, IL-10>34 pg/ml, CRP>10.84 mg/l on day 1 may suggest cardiovascular complications in STEMI patients within 1 year after the onset of the disease. We have not found reliable prognostic levels of IL-1β, as the concentration of this cytokine remained within the accepted normal range.. Discussion. It is concluded that initially elevated levels of CRP l, TNFα, IL-6, IL-10 in the blood make it possible to identify groups of patients with myocardial infarction with ST-segment elevation at high risk of cardiovascular events throughout the year.

scholarly journals Clinical Manifestation of Stressful Cardiomyopathy (Takotsubo Syndrome) and the Problem of Differential Diagnosis with Acute Myocardial Infarction

Kardiologiia ◽  
2020 ◽  
Vol 60 (11) ◽  
pp. 137-147
Author(s):  
E. S. Prokudina ◽  
B. K. Kurbatov ◽  
L. N. Maslov
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Differential Diagnosis ◽  
Troponin I ◽  
Single Photon ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Qtc Interval ◽  
St Segment Elevation ◽  
St Segment

The presented data show that tacotsubo syndrome (TS) is characterized by the absence of coronary artery obstruction, cardiac contractile dysfunction, apical ballooning, and heart failure, and in some patients, ST-segment elevation and prolongation of the QTc interval. Every tenth patient with TS develops ventricular arrhythmias. Most of TS patients have elevated markers of necrosis (troponin I, troponin Т, and creatine kinase МВ (CK-МВ), which are considerably lower than in patients with acute myocardial infarction (AMI) with ST-segment elevation. The level of N-terminal pro-B-type natriuretic peptide (NT-proBNP), in contrast, is considerably higher in patients with TS than with AMI. Differential diagnosis of TS and AMI should be based on a multifaceted approach using coronary angiography, echocardiography, analysis of ECG, magnetic resonance imaging, single-photon emission computed tomography, and measurement of troponins, CK-MB, and NT-proBNP.

scholarly journals Focal ST-segment elevation without coronary occlusion: myocardial infarction with no obstructive coronary atherosclerosis associated with COVID-19—a case report

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Casey Meizinger ◽  
Bruce Klugherz
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Respiratory Failure ◽  
Coronary Atherosclerosis ◽  
Myocardial Injury ◽  
Cardiovascular Complications ◽  
St Segment Elevation ◽  
St Segment ◽  
Hypoxic Respiratory Failure ◽  
Artery Disease

Abstract Background While it is understood that coronavirus disease 2019 (COVID-19) is primarily complicated by respiratory failure, more data are emerging on the cardiovascular complications of this disease. A subset of COVID-19 patients present with ST-elevations on electrocardiogram (ECG) yet normal coronary angiography, a presentation that can fit criteria for myocardial infarction with no obstructive coronary atherosclerosis (MINOCA). There is little known about non-coronary myocardial injury observed in patients with COVID-19, and we present a case that should encourage further conversation and study of this clinical challenge. Case summary An 86-year-old man presented to our institution with acute hypoxic respiratory failure and an ECG showing anteroseptal ST-segment elevation concerning for myocardial infarction. Mechanic ventilation was initiated prior to presentation, and emergent transthoracic echocardiography reported an ejection fraction of 50–55%, with no significant regional wall motion abnormalities. Next, emergent coronary angiography was performed, and no significant coronary artery disease was detected. The patient tested positive for COVID-19. Despite supportive management in the intensive care unit, the patient passed away. Discussion We present a case of COVID-19 that is likely associated with MINOCA. It is crucial to understand that in COVID-19 patients with signs of myocardial infarction, not all myocardial injury is due to obstructive coronary artery disease. In the case of COVID-19 pathophysiology, it is important to consider the cardiovascular effects of hypoxic respiratory failure, potential myocarditis, and significant systemic inflammation. Continued surveillance and research on the cardiovascular complications of COVID-19 is essential to further elucidate management and prognosis.

scholarly journals Stent Embolization Mimicking Acute Myocardial Infarction

2021 ◽  
Vol 9 ◽  
pp. 232470962110365
Author(s):  
Syed Arqum Huda ◽  
Sara Akram Kahlown ◽  
Anojan Pathmanathan ◽  
Muhammad Saad Farooqi ◽  
Mark Charlamb
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Stent Migration ◽  
Safe Procedure ◽  
Significant Morbidity ◽  
Fatal Complication ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment ◽  
Venous Stents

Venous thromboembolism is associated with significant morbidity and mortality if left untreated. Anticoagulation is the cornerstone of treatment. Venous stents are a relatively newer entity that are increasingly being used to treat venous stenosis/occlusion. It is a safe procedure, but complications include vein rupture, arterial puncture, retroperitoneal bleeding, and in-stent thrombosis. Stent migration is a rare but potentially fatal complication. We present a case of venous stent embolization to the heart that presented as a non-ST segment elevation myocardial infarction.

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