scholarly journals Features of pathomorphosis of gunshot wounds of the lungs

2021 ◽  
Vol 90 (1) ◽  
pp. 4-12
Author(s):  
Yu.V. Bunin ◽  
R.N. Mikhaylusov ◽  
V.V. Negoduyko ◽  
T.P. Yakimova
Keyword(s):  
Heart Failure ◽  
Gunshot Wound ◽  
Gunshot Wounds ◽  
Structure And Function ◽  
Lung Structure ◽  
Vascular Stenosis ◽  
Surgical Tactics ◽  
And Function ◽  
Methods Of Treatment

The article analyzes the results of pathomorphological changes of the lungs in the period from 1 day to 1.5 years after receiving a gunshot wound after a gunshot wound to the lungs. The features of the pathomorphosis of modern gunshot wounds of the lungs were determined in the dynamics to identify the optimal surgical tactics. It is found that impaired hemodynamics under the influence of firearms leads to the development of intoxication as a result of necrotic changes in the areola and to thrombosis with obstruction and vascular stenosis, and entails a cascade of local disorders of lung structure and function and as a consequence of pulmonary heart failure. The obtained morphological results of healing of gunshot wounds in the dynamics necessitate the search for new and optimization of existing methods of treatment of persons with gunshot wounds of the lungs in order to primarily optimize the preserved tissues. Keywords: morphological examinations, lungs, gunshot wound.

scholarly journals Lung ultrasound presentation of COVID-19 patients: phenotypes and correlations

2021 ◽  
Author(s):  
Gianmarco Secco ◽  
◽  
Marzia Delorenzo ◽  
Francesco Salinaro ◽  
Caterina Zattera ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Lung Ultrasound ◽  
Structure And Function ◽  
General Ward ◽  
Prognostic Role ◽  
Interstitial Syndrome ◽  
Lung Structure ◽  
And Function ◽  
The Relationship

AbstractBedside lung ultrasound (LUS) can play a role in the setting of the SarsCoV2 pneumonia pandemic. To evaluate the clinical and LUS features of COVID-19 in the ED and their potential prognostic role, a cohort of laboratory-confirmed COVID-19 patients underwent LUS upon admission in the ED. LUS score was derived from 12 fields. A prevalent LUS pattern was assigned depending on the presence of interstitial syndrome only (Interstitial Pattern), or evidence of subpleural consolidations in at least two fields (Consolidation Pattern). The endpoint was 30-day mortality. The relationship between hemogasanalysis parameters and LUS score was also evaluated. Out of 312 patients, only 36 (11.5%) did not present lung involvment, as defined by LUS score < 1. The majority of patients were admitted either in a general ward (53.8%) or in intensive care unit (9.6%), whereas 106 patients (33.9%) were discharged from the ED. In-hospital mortality was 25.3%, and 30-day survival was 67.6%. A LUS score > 13 had a 77.2% sensitivity and a 71.5% specificity (AUC 0.814; p < 0.001) in predicting mortality. LUS alterations were more frequent (64%) in the posterior lower fields. LUS score was related with P/F (R2 0.68; p < 0.0001) and P/F at FiO2 = 21% (R2 0.59; p < 0.0001). The correlation between LUS score and P/F was not influenced by the prevalent ultrasound pattern. LUS represents an effective tool in both defining diagnosis and stratifying prognosis of COVID-19 pneumonia. The correlation between LUS and hemogasanalysis parameters underscores its role in evaluating lung structure and function.

scholarly journals Comorbidity and Ventricular and Vascular Structure and Function in Heart Failure With Preserved Ejection Fraction

2012 ◽  
Vol 5 (6) ◽  
pp. 710-719 ◽  
Author(s):  
Selma F. Mohammed ◽  
Barry A. Borlaug ◽  
Véronique L. Roger ◽  
Sultan A. Mirzoyev ◽  
Richard J. Rodeheffer ◽  
...  
Keyword(s):  
Heart Failure ◽  
Ejection Fraction ◽  
Structure And Function ◽  
Vascular Structure ◽  
Preserved Ejection Fraction ◽  
And Function

Lung Structure And Function Relation In Elastase-Treated Rats: A Long-Term Follow Up Study

2012 ◽  
Author(s):  
Margit V. Szabari ◽  
Jozsef Tolnai ◽  
Balazs Maar ◽  
Harikrishnan Parameswaran ◽  
Elizabeth Bartolak-Suki ◽  
...  
Keyword(s):  
Structure And Function ◽  
Follow Up Study ◽  
Lung Structure ◽  
Long Term Follow Up ◽  
And Function ◽  
Function Relation

scholarly journals Hyperinsulinemia adversely affects lung structure and function

2016 ◽  
Vol 310 (9) ◽  
pp. L837-L845 ◽  
Author(s):  
Suchita Singh ◽  
Manish Bodas ◽  
Naveen K. Bhatraju ◽  
Bijay Pattnaik ◽  
Atish Gheware ◽  
...  
Keyword(s):  
Insulin Treatment ◽  
Epithelial Mesenchymal Transition ◽  
Respiratory Health ◽  
Structure And Function ◽  
Intranasal Insulin ◽  
Mesenchymal Transition ◽  
Inhaled Insulin ◽  
Lung Structure ◽  
Prevalence Of Obesity ◽  
And Function

There is limited knowledge regarding the consequences of hyperinsulinemia on the lung. Given the increasing prevalence of obesity, insulin resistance, and epidemiological associations with asthma, this is a critical lacuna, more so with inhaled insulin on the horizon. Here, we demonstrate that insulin can adversely affect respiratory health. Insulin treatment (1 μg/ml) significantly ( P < 0.05) increased the proliferation of primary human airway smooth muscle (ASM) cells and induced collagen release. Additionally, ASM cells showed a significant increase in calcium response and mitochondrial respiration upon insulin exposure. Mice administered intranasal insulin showed increased collagen deposition in the lungs as well as a significant increase in airway hyperresponsiveness. PI3K/Akt mediated activation of β-catenin, a positive regulator of epithelial-mesenchymal transition and fibrosis, was observed in the lungs of insulin-treated mice and lung cells. Our data suggests that hyperinsulinemia may have adverse effects on airway structure and function. Insulin-induced activation of β-catenin in lung tissue and the contractile effects on ASM cells may be causally related to the development of asthma-like phenotype.

Perinatal Inflammation Negatively Impacts Lung Structure And Function In Adult Mice

2012 ◽  
Author(s):  
Markus Velten ◽  
Rodney D. Britt ◽  
Kathryn M. Heyob ◽  
Trent E. Tipple ◽  
Lynette K. Rogers
Keyword(s):  
Structure And Function ◽  
Adult Mice ◽  
Lung Structure ◽  
And Function

CT-Derived Pulmonary Vascular Volume And Lung Structure And Function In Humans

2012 ◽  
Author(s):  
Sarah Lau ◽  
Courtney M. Wheatley ◽  
Eric C. Wong ◽  
Nicholas A. Cassuto ◽  
Cori L. Daines ◽  
...  
Keyword(s):  
Structure And Function ◽  
Vascular Volume ◽  
Lung Structure ◽  
And Function
Sign in / Sign up

Export Citation Format

Share Document