scholarly journals CLINICAL SIGNIFICANCE OF LAMININ AND ELASTINE LEVELS IN CHILDREN WITH UNDIFFERENTIATED CONNECTIVE TISSUE DISEASE

2021 ◽  
Vol 11 (2) ◽  
pp. 78-79
Author(s):  
Nikolay Cherkasov ◽  
Yuliya Lutsenko
Keyword(s):  
Early Detection ◽  
Connective Tissue ◽  
Clinical Significance ◽  
Connective Tissue Disease ◽  
Clinical Laboratory ◽  
Undifferentiated Connective Tissue Disease

This research aims to study levels of laminin and elastine in 64 children with undifferentiated connective tissue disease (UCTD). All the children underwent clinical, laboratory and instrumental examination. It was found that changes in the levels of laminin and elastin are directly related to the severity of UCTD in children. Thus, clinical values of laminin and elastin levels can serve as additional criteria of UCTD severity. Using them, along with early detection of the phenotypic and visceral signs, helps prevent the development of severe forms of the disease.

scholarly journals Kingella kingae Intrauterine Infection: An Unusual Cause of Chorioamnionitis and Miscarriage in a Patient with Undifferentiated Connective Tissue Disease

Diagnostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 243
Author(s):  
Maria Paola Bonasoni ◽  
Andrea Palicelli ◽  
Giulia Dalla Dea ◽  
Giuseppina Comitini ◽  
Giulia Pazzola ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Medical Treatment ◽  
Connective Tissue Disease ◽  
Lupus Erythematosus ◽  
Etiologic Agent ◽  
Intrauterine Fetal Death ◽  
Severe Neutropenia ◽  
Invasive Infection ◽  
Undifferentiated Connective Tissue Disease ◽  
Kingella Kingae

Kingella kingae is a Gram-negative coccobacillus belonging to the Neisseriaceae family. In children less than 4 years old, K. kingae invasive infection can induce septic arthritis and osteomyelitis, and more rarely endocarditis, meningitis, ocular infections, and pneumonia. In adults, it may be a cause of endocarditis. To date, K. kingae acute chorioamnionitis (AC) leading to preterm rupture of membranes (PPROM) and miscarriage has never been reported. Herein, we describe a case of intrauterine fetal death (IUFD) at 22 weeks’ gestation due to K. kingae infection occurred in a patient affected by undifferentiated connective tissue disease (UCTD) in lupus erythematosus systemic (LES) evolution with severe neutropenia. K. kingae was isolated in placental subamnionic swab and tissue cultures as well as fetal ear, nose, and pharyngeal swabs. Placental histological examination showed necrotizing AC and funisitis. In the fetus, neutrophils were observed within the alveoli and in the gastrointestinal lumen. Maternal medical treatment for UCTD was modified according to the K. kingae invasive infection. In the event of IUFD due to AC, microbiological cultures on placenta and fetal tissues should always be carried out in order to isolate the etiologic agent and target the correct medical treatment.

scholarly journals Impaired endothelial function in patients with undifferentiated connective tissue disease: a follow-up study

Rheumatology ◽  
2014 ◽  
Vol 53 (11) ◽  
pp. 2035-2043 ◽  
Author(s):  
R. Laczik ◽  
P. Soltesz ◽  
P. Szodoray ◽  
Z. Szekanecz ◽  
G. Kerekes ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Endothelial Function ◽  
Connective Tissue Disease ◽  
Undifferentiated Connective Tissue Disease ◽  
Follow Up Study

scholarly journals Rhabdomyolysis-induced acute kidney injury in a patient with undifferentiated connective tissue disease

Medicine ◽  
2019 ◽  
Vol 98 (30) ◽  
pp. e16492 ◽  
Author(s):  
Hongxia Mai ◽  
Yuliang Zhao ◽  
Stephen Salerno ◽  
Yi Li ◽  
Letian Yang ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Kidney Injury ◽  
Undifferentiated Connective Tissue Disease

Podocyte infolding glomerulopathy with undifferentiated connective tissue disease: a case report

2020 ◽  
Vol 44 (2) ◽  
pp. 245-248
Author(s):  
Jiaoyu Shi ◽  
Rong Zheng ◽  
Hongyang Gao ◽  
Zhonghua Zhao ◽  
Huijuan Wu ◽  
...  
Keyword(s):  
Case Report ◽  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Undifferentiated Connective Tissue Disease ◽  
Podocyte Infolding

scholarly journals Alfacalcidol treatment restores derailed immune-regulation in patients with undifferentiated connective tissue disease

2011 ◽  
Vol 10 (3) ◽  
pp. 155-162 ◽  
Author(s):  
Eva Zold ◽  
Peter Szodoray ◽  
Britt Nakken ◽  
Sandor Barath ◽  
Janos Kappelmayer ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Immune Regulation ◽  
Undifferentiated Connective Tissue Disease
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