EFFICACY OF INTRAPERITONEAL INSTILLATION OF 0.2% ROPIVACAINE FOR POSTOPERATIVE PAIN RELIEF AFTER LAPAROSCOPIC CHOLECYSTECTOMY

2021 ◽  
pp. 13-15
Author(s):  
Debottam Gangopadhyay ◽  
Rahul Agarwal

INTRODUCTION: Postoperative pain management is one of most important components of adequate postoperative patient care. Poorly treated pain contributes to patient suffering and may prevent rapid recovery and rehabilitation. Laparoscopic operative procedures have revolutionized surgery with many advantages : a smaller and more cosmetic incision, reduced blood loss, reduced postoperative hospital stay and pain, which cut 1 down hospital costs . AIMS AND OBJECTIVES:Aim of the study is to evaluate the efcacy of intraperitoneal instillation of ropivacaine for postoperative pain relief after laparoscopic cholecystectomy surgeries in terms of : Duration of analgesia, 24 hour postoperative analgesic requirement, Postoperative pain assessment, Postoperative hemodynamic changes like pulse rate, blood pressure and Complications (if any). MATERIALS AND METHODS: Study area -Command Hospital (Eastern Command), Alipore, Kolkata (operation theatre and ward). Study population - Patients posted for Elective Laparoscopic Cholecystectomy. Study period -Jan 2017 to June 2018 Study Time– From rst intraoperative intraperitoneal instillation of study drug to next 24 postoperative hours. Sample Size - 80 (40 in each group) RESULTS AND ANALYSIS: In our study, intraperitoneal instillation of Ropivacaine at the end of surgery provided analgesia for 5.54 ± 4.61 hrs. When compared with the saline group, it was about 2.22 ± 2.93 hrs, which was found to be statistically signicant (-0.004). In this study, Injection Tramadol was used for rescue analgesia for postoperative pain relief. SUMMARYAND CONCLUSION: This study has a few limitations. First, eighty study population may be underpowered for the study. Second, the surgeon performing the surgeries is not the same in every case which may alter the postoperative consequences. From this study it may be concluded that intraperitoneal instillation of Ropivacaine is effective for postoperative pain relief after laparoscopic cholecystectomy. From this study we also conclude that, intraperitoneal instillation of Ropivacaine is useful for postoperative pain relief for patients undergoing laparoscopic cholecystectomy in terms of duration of analgesia, rescue analgesic requirement and pain perception.

2021 ◽  
Vol 28 (02) ◽  
pp. 192-196
Author(s):  
Nadia Bano ◽  
Nazim Hayat ◽  
Saira Saleem ◽  
Farhan Javaid ◽  
Ayesha Rehman ◽  
...  

Objective: To compare the effects of intraincisional and intraperitoneal infiltration of local anaesthetic to relieve early postoperative pain in laparoscopic cholecystectomy. Study Design: Randomized Control Trial. Setting: Department of Anaesthesia and Surgery, Madinah Teaching Hospital Faisalabad. Period: July 2017 to March 2018. Material & Methods: A sample of 100 patients with American Society of Anaesthesiologists Physical status (ASA) I and II, undergoing laparoscopic cholecystectomy were selected using simple random sampling technique. Patients were randomly assigned into groups A and B. Group A patients received intraperitoneal infiltration of 20 ml solution of 0.25% bupivacaine and group B patients received intraincisional infiltration of 20 ml solution of 0.25% bupivacaine. Results:  Demographic characteristics were not significantly different in both groups. Our study showed that Group A patients had better pain relief as compared to group B patients. Visual analogue score (VAS) for pain relief at 0, 3,6,12 and 24 hours was statistically different in both groups. The requirement of rescue analgesia between group A and B was found to be12% and 38% which is statically significant (p value 0.003). Conclusion: intraperitoneal infiltration of Bupivacaine offers better postoperative pain relief after laparoscopic cholecystectomy and is associated with less analgesic requirement in early postoperative period.


2021 ◽  
pp. 16-19
Author(s):  
Nimta Kishore ◽  
Trilok Chand ◽  
Narendra Singh Poniya ◽  
Arpita Saxena

Introduction: Laparoscopic cholecystectomy is a minimally invasive surgical procedure for cholecystectomy. In present time local anesthesia is widely used as analgesic by various routes including port site intraincisional inlteration, transverse abdominis plane (TAP) block and intraperitoneal instillation. Aim: Comparing The Post-Operative Analgesia Using Ropivacaine in Laparoscopic Cholecystectomy by three Different Methods ; Intraperitoneal instillation, USG-guided subcostal transversus abdominis plane block and Incisional inltration at port site. Materials and methods: This study was conducted among elective general surgical patient undergoing laparoscopic cholecystectomy in S.N. Medical College, Agra and completed in the study period of 18 months. Study population was elective surgical patients posted for elective laparoscopic cholecystectomy. Patients were divided in to 3 groups: Group A- Intraperitoneal instillation, Groups B- ultrasound guided subcostal transversus abdominis plane block and Groups C- intraincisional inlteration at port site. Results: Intraincisional inltration of ropivacaine provide signicant Postoperative pain relief in comparative to USG -guided subcostal TAP block and intraperitoneal instillation with ropivacaine. Conclusion: Intraincisional inltration of ropivacaine provide signicant Postoperative pain relief and decrease post operative analgesia requirement in comparative to USG -guided subcostal TAP block and intraperitoneal instillation with ropivacaine. Shoulder tip pain incidence, postoperative nausea and vomiting incidence lower in intraincisional inltration of ropivacaine.


2018 ◽  
Vol 5 (4) ◽  
pp. 1538
Author(s):  
Ravishankar N. ◽  
Arun Kumar A. A. ◽  
Tulasi Vasudevaiah

Background: Laparoscopy involves insufflation of the abdomen by gas, so that the scope (usually 6-10 mm in diameter) can view the intra-abdominal contents without being in direct contact with the viscera or tissues. Surgical procedures can be carried out by instruments produced through one or more additional ports.Methods: This study was conducted in 60 patients aged 30-50 years. The patients were divided into two Groups A: 0.5 Bupivacaine, B: Saline intraperitoneal instillation; 30 patients in each group undergoing elective surgery.Results: This study was undertaken to compare the post-operative analgesic effect of 20 mL 0.5% Bupivacaine given intraperitoneally at the end of laparoscopic surgery with control 0.9% saline 20 mL at Bupivacaine group had better postoperative pain relief in the first six hours with no complications.Conclusions: 0.5% Bupivacaine irrigation at the surgical bed is effective for cholecystectomy for postoperative pain relief.


2021 ◽  
pp. 76-77
Author(s):  
Deepti Chauhan ◽  
Satyendra Yadav ◽  
Heena Sheikh ◽  
Ashish Mathur

AIMS AND OBJECTIVES: To evaluate the efcacy of duloxetine in different doses in postoperative pain relief in patients undergoing lumbar spine surgery. MATERIALAND METHOD: 80 patients of ASA grade І & ІІ of either sex scheduled for lumbar spine surgery under general anaesthesia were divided into 2 groups (n=40 each) randomly.Group D (n=40) Patients who received a 60 mg duloxetine 1 hour before surgery and another tablet the following morning. Group 'P'(n=40) Patients who received a placebo tablet 1 hour before surgery and again the following morning. Pulse rate, blood pressure, respiratory rate and severity of pain on NRS scale was noted at 0 hr, 4 hr, 8 hr, 12 hr, 16 hr, 20 hr, 24 hr, 28 hr, 32 hr and 48 hr after surgery. And the presence or absence of adverse effects, such as headache, nausea, vomiting, dizziness, and drowsiness were noted. RESULT: Analysis revealed that time for rst analgesic requirement was signicantly longer with oral Duloxetine 60 mg than with placebo. Pre-emptive oral Duloxetine 60 mg decreases the severity of pain postoperatively but not signicantly as compared to placebo in patients posted for lumbar spine surgery under general anaesthesia. Oral Duloxetine 60 mg had no signicant effect on cardiovascular and respiratory parameters. Patients receiving duloxetine had higher incidence of nausea, vomiting. CONCLUSION:that time for rst analgesic requirement was signicantly longer with oral Duloxetine 60 mg than placebo.


2002 ◽  
Vol 95 (2) ◽  
pp. 450-456 ◽  
Author(s):  
Anil Gupta ◽  
Sven E. Thörn ◽  
Kjell Axelsson ◽  
Lars G. Larsson ◽  
Göran Ågren ◽  
...  

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