scholarly journals TO ASSESS THE DOSIMETRIC IMPACT ON PROSTATE, BLADDER AND RECTUM IN CARCINOMA PROSTATE DUE TO INTERFRACTIONALANATOMICAL VARIATION IN IMAGE GUIDED RADIATION THERAPY.

2020 ◽  
pp. 1-3
Author(s):  
Abhilasha Abhilasha ◽  
Sweta Soni ◽  
Amrita Rakesh ◽  
Nidhi Patni
Keyword(s):  
Prostate Cancer ◽  
Anatomical Variation ◽  
Intensity Modulated Radiotherapy ◽  
Target Volume ◽  
Mean Value ◽  
Prostate Radiotherapy ◽  
Image Guided Radiation Therapy ◽  
Filling Materials ◽  
Geographic Miss ◽  
Critical Structure

ABTRACT- Prostate cancer is second most frequent cancer in men and fifth leading cause of death worldwide. Most radiotherapy patients with prostate cancer are treated with intensity modulated radiotherapy. IMRT requires high spatial accuracy in localizing the target volume and high precision in treatment delivery, because even a small geographic miss can have a large dosimetric effect. However, the patient setup position and anatomy changes daily, particularly in the prostate region, due to rectum and bladder filling. Materials Methods: We analyzed 30 patients with prostate cancer patient treated with IMRT kV CBCT was performed for each patient twice per week during the entire course of treatment. The bladder, rectum, prostate and PTV were contoured on each CBCT scan. Results: Delivered dose of prostate D95% and prostate D100% was 99.15% and 93.66% respectively and mean value of V70 for bladder was 16% and delivered value was 16.45%. Whereas the mean value of V70 of plan for rectum was 18.12% and delivered value was 27.58%. Conclusion: Interfractional variation during prostate radiotherapy can results in substantial difference between planned and delivered doses, particularly in critical structure. IG-IMRT is useful tool in assessing dosimetric changes in critical structure due to interfractional anatomical interfractional anatomical variation in prostate radiotherapy.

scholarly journals Dosimetry of conformal dynamic arc radiotherapy and intensity modulated radiotherapy in unresectable cholangiocarcinoma

2010 ◽  
Vol 4 (1) ◽  
pp. 131-139
Author(s):  
Thanarpan Peerawong ◽  
Chonlakiet Khorprasert ◽  
Sivalee Suriyapee ◽  
Taweap Sanghangthum ◽  
Isra Israngkul Na Ayuthaya ◽  
...  
Keyword(s):  
Planning Target Volume ◽  
Left Kidney ◽  
Intensity Modulated Radiotherapy ◽  
Target Volume ◽  
Intensity Modulated ◽  
Dose Volume ◽  
Organ At Risk ◽  
The Right ◽  
Upper Abdomen ◽  
Critical Structure

Abstract Background: Radiotherapy in cholangiocrcinoma has to overcome organ tolerance of the upper abdomen. Hi-technology radiotherapy may improve conformity and reduce dose to those organ. Objective: Quantitatively compare the dosimetry of conformal dynamic arc radiotherapy (CD-arcRT) and intensity modulated radiotherapy (IMRT) in unresectable cholangiocarcinoma. Material and methods: Eleven cases of unresectable cholangiocarcinoma were re-planned with IMRT and CDarcRT at King Chulalongkhorn Memorial Hospital between 20 September 2004 and 31 December 2005. Both the planning techniques were evaluated using the dose volume histogram of the planning target volume and organ at risk. The conformation number and dose to critical normal structures were used to determine the techniques. Results: IMRT technique was significantly conformed to the planning target volume than CD-arcRT in term of conformation number. For critical structure, IMRT significantly reduced the radiation dose to liver in terms of mean liver dose, V30Gy and V20Gy of the right kidney. Conclusion: The advantage of IMRT was more conformity and reduced dose to critical structure compared with CD-arcRT, but there was no difference between these techniques in terms of V20Gy of left kidney and maximum dose to the spinal cord.

Transperineal ultrasound for aiding target volume delineation and monitoring during prostate cancer radiotherapy in men with bilateral hip prostheses

2020 ◽  
pp. 1-5
Author(s):  
Serena Jayne Hilman ◽  
Thomas Bird ◽  
Piotr Gieryluk ◽  
Amy Richardson ◽  
Petra Jacobs
Keyword(s):  
Volumetric Modulated Arc Therapy ◽  
Intensity Modulated Radiotherapy ◽  
Target Volume ◽  
Transperineal Ultrasound ◽  
Ultrasound Images ◽  
Hip Prostheses ◽  
Prostate Radiotherapy ◽  
Volume Delineation ◽  
Consistent Change ◽  
Metal Artefact Reduction Algorithm

Abstract Aims: To investigate the use of co-registration of the computerised tomography (CT) planning scan with transperineal ultrasound (TPUS) as an aid to the delineation of the clinical target volume (CTV), and the use of TPUS as a tool for inter- and intra-fractional monitoring in men with bilateral hip prostheses (b-P) undergoing prostate radiotherapy. Materials and methods: We marked the CTV of three patients with and without the co-registered TPUS images. A metal artefact reduction algorithm was utilised. Two patients were treated with intensity-modulated radiotherapy (IMRT) and one with volumetric-modulated arc therapy (VMAT). The inter- and intra-fractional monitoring details were reviewed retrospectively. Results: Clinician marking with TPUS/CT fusion improved the confidence of prostate CTV delineation leading to a consistent change in volumes across two observers. Inter- and intra-fractional monitoring was possible using TPUS as image guidance, as it is for those patients with non-prosthetic hips. Findings: Using TPUS in the radiotherapy workflow has enabled us to more confidently plan, treat and monitor patients with b-HP. Due to transperineal image acquisition, the ultrasound images are not affected by the presence of hip prostheses, which are outside the field of view.

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