“A COMPARATIVE STUDY TO EVALUATE THE EFFICACY OF IN POSTOPERAT ETORICOXIB IN PAIN RELIEF IN PATIENTS IN UNDERGOING LUMBAR SPINE SURGERY ”

2021 ◽  
pp. 65-66
Author(s):  
Deepti chauhan ◽  
Ashish Mathur ◽  
Sukhnandan Singh Tomar ◽  
Heena sheikh
Keyword(s):  
Blood Pressure ◽  
Lumbar Spine ◽  
Pain Relief ◽  
General Anaesthesia ◽  
Spine Surgery ◽  
Lumbar Spine Surgery ◽  
Analgesic Requirement ◽  
Placebo Tablet ◽  
Respiratory Parameters ◽  
Different Doses

AIMS AND OBJECTIVES: To evaluate the efcacy of Etoricoxib in different doses in postoperative pain relief in patients undergoing lumbar spine surgery. MATERIALAND METHOD : 80 patients of ASA grade І & ІІ of either sex scheduled for lumbar spine surgery under general anaesthesia were divided into 2 groups (n=40 each) randomly.Group E (n=40) Patients who received a 90 mg Etoricoxib 1 hour before surgery and another tablet the following morning. Group 'P'(n=40) Patients who received a placebo tablet 1 hour before surgery and again the following morning. Pulse rate, blood pressure, respiratory rate and severity of pain on NRS scale was noted at 0 hr, 4 hr, 8 hr, 12 hr, 16 hr, 20 hr, 24 hr, 28 hr, 32 hr and 48 hr after surgery. And the presence or absence of adverse effects, such as headache, nausea, vomiting, dizziness, and drowsiness were noted. RESULT:Analysis revealed that time for rst analgesic requirement was signicantly longer with oral Etoricoxib 90 mg than with placebo. Pre-emptive oral Etoricoxib 90 mg decreases the severity of pain postoperatively but not signicantly as compared to placebo in patients posted for lumbar spine surgery under general anaesthesia. Oral Etoricoxib 90 mg had no signicant effect on cardiovascular and respiratory parameters. Patients receiving Etoricoxib had higher incidence of nausea, vomiting. CONCLUSION: that time for rst analgesic requirement was signicantly longer with oral Etoricoxib than placebo.

“A COMPARATIVE STUDY TO EVALUATE THE EFFICACY OF DULOXETINE IN POSTOPERATIVE PAIN RELIEF IN PATIENTS IN UNDERGOING LUMBAR SPINE SURGERY ”

2021 ◽  
pp. 76-77
Author(s):  
Deepti Chauhan ◽  
Satyendra Yadav ◽  
Heena Sheikh ◽  
Ashish Mathur
Keyword(s):  
Lumbar Spine ◽  
Postoperative Pain ◽  
Pain Relief ◽  
General Anaesthesia ◽  
Spine Surgery ◽  
Postoperative Pain Relief ◽  
Lumbar Spine Surgery ◽  
Analgesic Requirement ◽  
Respiratory Parameters ◽  
Result Analysis

AIMS AND OBJECTIVES: To evaluate the efcacy of duloxetine in different doses in postoperative pain relief in patients undergoing lumbar spine surgery. MATERIALAND METHOD: 80 patients of ASA grade І & ІІ of either sex scheduled for lumbar spine surgery under general anaesthesia were divided into 2 groups (n=40 each) randomly.Group D (n=40) Patients who received a 60 mg duloxetine 1 hour before surgery and another tablet the following morning. Group 'P'(n=40) Patients who received a placebo tablet 1 hour before surgery and again the following morning. Pulse rate, blood pressure, respiratory rate and severity of pain on NRS scale was noted at 0 hr, 4 hr, 8 hr, 12 hr, 16 hr, 20 hr, 24 hr, 28 hr, 32 hr and 48 hr after surgery. And the presence or absence of adverse effects, such as headache, nausea, vomiting, dizziness, and drowsiness were noted. RESULT: Analysis revealed that time for rst analgesic requirement was signicantly longer with oral Duloxetine 60 mg than with placebo. Pre-emptive oral Duloxetine 60 mg decreases the severity of pain postoperatively but not signicantly as compared to placebo in patients posted for lumbar spine surgery under general anaesthesia. Oral Duloxetine 60 mg had no signicant effect on cardiovascular and respiratory parameters. Patients receiving duloxetine had higher incidence of nausea, vomiting. CONCLUSION:that time for rst analgesic requirement was signicantly longer with oral Duloxetine 60 mg than placebo.

Use of intrathecal morphine for postoperative pain relief following lumbar spine surgery

1985 ◽  
Vol 63 (3) ◽  
pp. 413-416 ◽  
Author(s):  
Padraic O'Neill ◽  
Christine Knickenberg ◽  
Senarath Bogahalanda ◽  
Anthony E. Booth
Keyword(s):  
Lumbar Spine ◽  
Postoperative Pain ◽  
Pain Relief ◽  
Spine Surgery ◽  
Intrathecal Morphine ◽  
Postoperative Pain Relief ◽  
Lumbar Spine Surgery ◽  
Double Blind ◽  
Content Type ◽  
The Mean

✓ A randomized prospective double-blind trial of intrathecal morphine for postoperative pain relief following lumbar spine surgery is described. Intrathecal morphine significantly reduced the mean pain score in the postoperative period (p < 0.01) and there was a corresponding significant reduction in the need for additional postoperative analgesia (p < 0.05). The possible mechanism of action of intrathecal morphine and the potential advantages of this technique are discussed. Possible side effects are also considered, and caution is urged until wider experience has been obtained.

Ischemic optic neuropathy following lumbar spine surgery

1995 ◽  
Vol 83 (2) ◽  
pp. 348-349 ◽  
Author(s):  
Andrew G. LEE
Keyword(s):  
Blood Pressure ◽  
Lumbar Spine ◽  
Spine Surgery ◽  
Optic Neuropathy ◽  
Visual Loss ◽  
Lumbar Spine Surgery ◽  
Ischemic Optic Neuropathy ◽  
Content Type ◽  
The Right ◽  
Fine Print

✓ This 48-year-old hypertensive man, a cigarette smoker, awoke in the recovery room with visual loss in the right eye after uncomplicated lumbar spine surgery. His intraoperative blood pressure had been maintained at relatively low levels to reduce bleeding; a loss of 1500 cc of blood was reported. Postoperative hemoglobin was 4.2 g/dl less than the preoperative hemoglobin; however, the patient did not receive a blood transfusion. A postoperative ophthalmological examination revealed decreased visual acuity, color vision, and visual field in the right eye. The right optic nerve and retina were initially normal but the patient eventually developed optic nerve atrophy consistent with the clinical diagnosis of ischemic optic neuropathy. Neurosurgeons should be aware that this condition may follow uncomplicated lumbar spine surgery and should obtain prompt ophthalmological consultation when patients develop postoperative visual loss. Aggressive and rapid correction of blood pressure and hematocrit may be helpful in individuals who develop ischemic optic neuropathy after lumbar spine surgery.

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