scholarly journals A COMPARATIVE ANALYSIS OF FNAC AND BIRADS IN EVALUATION OF PALPABLE BREAST LUMP

2021 ◽  
pp. 29-31
Author(s):  
Pooja ranjan ◽  
Joyeeta Mandal ◽  
Anshu jamaiyar ◽  
Sunil Kumar Mahto
Keyword(s):  
Breast Lesion ◽  
Giemsa Stain ◽  
Breast Lesions ◽  
Breast Lump ◽  
Diagnostic Modality ◽  
Treatment Protocols ◽  
Common Complaint ◽  
Accurate Preoperative Diagnosis ◽  
Preoperative Diagnostic ◽  
Palpable Breast

Breast lump is one of the most common complaint among female patients in India. FNAC is one of the important preoperative diagnostic modality in case of breast lesion. Correlation between BIRADS category and cytological findings are useful to establish an accurate preoperative diagnosis and further treatment protocols. In the present study, FNAC smear were stained by Leishman & Giemsa stain. Reporting was done in correlation with BIRADS category. Our study consisted of 80 cases of palpable breast lesions, of which 54 were benign and 26 malignant. The study showed overall 8 1.25% concordance with BIRADS category

scholarly journals Fine needle aspiration cytology (FNAC) in pre-operative diagnosis of breast lesions in Kadapa region of Andhra Pradesh, India

2017 ◽  
Vol 4 (12) ◽  
pp. 4062
Author(s):  
Chakarala Obula Reddy ◽  
Garisa Chandra Mohana Reddy
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Breast Lesions ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Palpable Breast ◽  
Needle Aspiration Cytology

Background: Various diagnostic methods have been developed to evaluate the palpable and non-palpable breast lesions, but Fine needle aspiration cytology of the palpable breast masses have become increasingly popular as a diagnostic technique to assess the breast lesions. To study the role of FNAC in diagnosis of breast lumps.Methods: 60 female patients (11-74 years age group) with palpable breast lump were utilized to study the role of Fine needle aspiration cytology for clinically palpable breast lump was carried out in Fathima Institute of Medical Sciences, Kadapa, Andhra Pradesh.Results: Fine needle aspiration cytology revealed benign in 22 patients, suspicious in 3 and 35 malignant lesions were 93.10% with false negative rate of 6.9% and false positive rate of 0%. The overall sensitivity of fine needle aspiration cytology in diagnosing the palpable breast lump in our study was 93.10%, specificity was 100%, positive predictive of 100% and negative predictive value of 90.47%.Conclusions: FNAC is easy to perform and painless procedure and standard tool for diagnosis of breast lumps with high percentage of true positives without virtual complications.

scholarly journals The Efficacy and Safety of Indocyanine green- hyaluronic acid mixture (LuminoMarkTM) for Localization in Patients with Non-palpable Breast Lesions: A Multi-center Open-label Parallel Phase-2 Clinical trial

2020 ◽  
Author(s):  
Isaac Kim ◽  
Hee Jun Choi ◽  
Jai Min Ryu ◽  
Se Kyung Lee ◽  
Jong Han Yu ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Hyaluronic Acid ◽  
Breast Lesion ◽  
Ultrasound Image ◽  
Test Group ◽  
Acid Mixture ◽  
Control Group ◽  
Breast Lesions ◽  
Efficacy And Safety ◽  
Palpable Breast

Abstract Backgrounds With increasing screening for breast cancer, non-palpable breast lesions are detected more frequently. A preoperative localization is very important for a minimal but accurate excision of a non-palpable breast lesion. The purpose of this study was to evaluate the efficacy and safety of indocyanine green(ICG)-hyaluronic acid mixture injection as a novel material for localization. Methods We performed prospective clinical trial with female patients who underwent surgery for non-palpable breast lesion. 44 patients were sequentially assigned to the control group(localization with activated charcoal), test group 1(ICG-hyaluronic acid mixture 0.1ml), or test group 2(ICG-hyaluronic acid mixture 0.2ml) by 1:1:1 ratio. Results Most were over 40 years old, and there were no differences between three groups in age distribution. According to the pathologic results, fibroadenoma accounted for the largest share (38.6%, 17/44) and malignancy accounted for 11.4% (5/44). The marking rate on both breast lesions and excised specimens was over 86% in all groups, and there was no difference. However, skin pigmentation was only in the control group and the accuracy of resection (the greatest length in cm of the excised specimen divided by the greatest length in cm on the pre-operation ultrasound image, the value closer to 1 meant resection as much as the size on ultrasound image) was different significantly. The average was 3.7(range 1.2-13.3) in control group and 2.2 (1.0-4.2) in test 1 group and 2.1(1.0-4.2) in test 2 group. Conclusion ICG-hyaluronic acid mixture injection was superior to activated charcoal for localization in patients with non-palpable breast lesions.

scholarly journals X-ray and Ultrasound Localization of Non-Palpable Breast Lesions and Difficulties in Management

1987 ◽  
Vol 80 (11) ◽  
pp. 678-680 ◽  
Author(s):  
J J T Tate ◽  
G T Royle ◽  
P McDonald ◽  
P B Guyer ◽  
I Taylor
Keyword(s):  
Breast Lesion ◽  
Careful Examination ◽  
Breast Lesions ◽  
Residual Cancer ◽  
X Ray ◽  
Ultrasound Localization ◽  
Biopsy Site ◽  
Operative Specimen ◽  
Asymptomatic Patients ◽  
Palpable Breast

Seventy-four patients who have had biopsy of a non-palpable breast lesion are reviewed. A double-dye localization technique was used in 88% while in 12% localization of the lesion was best achieved by ultrasound mammography. Biopsy was successful in 70 patients (95%) at the first attempt. The overall incidence of malignancy was 20%, being greater in asymptomatic patients (32%) than in patients with mastalagia (16%). Re-excision of the biopsy site in these patients showed residual cancer in 33%. It is suggested that both careful examination of the operative specimen and postoperative mammography may be necessary to ensure that the original lesion has been removed. Re-excision of the biopsy site appears to be necessary when the histology is malignant.

scholarly journals Update on Management of Non-Palpable Breast Lesion

2020 ◽  
Vol 14 (2) ◽  
pp. 93-99
Author(s):  
Ali Nafisa ◽  
SK Farid Ahmed ◽  
Md Ahasanul Alam ◽  
Shoeb Sarwar Murad ◽  
ASM Tanjilur Rahman ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Lesion ◽  
Public Awareness ◽  
Radical Mastectomy ◽  
Complete Removal ◽  
Breast Conserving Surgery ◽  
Breast Lesions ◽  
Oncological Safety ◽  
Palpable Breast ◽  
Magnetic Seeds

Halstedian radical mastectomy is practiced over 40 years as surgical treatment of breast cancer. For the last twenty years, breast conserving surgery (BCS) has been more practiced in the treatment of breast cancer as it provides oncological safety as well as cosmesis. Non palpable breast lesions are being increasingly diagnosed in the recent years as a result of introduction of breast cancer screening, high quality digital mammography and increase in public awareness. Accurate localisation of small, nonpalpable breast lesions is mandatory for accurate surgical management. The purpose of this article is to review the techniques systematically those have been used to locate non-palpable breast lesions which could easily be introduced in Bangladesh. Breast conserving surgery means complete removal of the tumour with a concentric margin of surrounding healthy tissue with maintenance of acceptable cosmesis. It should be followed by radiation therapy (RT) to achieve an acceptably low rate of local recurrence. Breast conserving surgery with radiotherapy has same survival benefit as mastectomy. BCS plus RT provided better outcome than mastectomy for early breast cancer and should be offered as a preferred treatment option. Experience, logistical support, and multidisciplinary approach is key to success. Radiological support with ultrasound or stereotactic localization with wires and /or ultrasound skin marking are key to have accurate wide local excision of non palpable lesions which is gold standard. Other newer techniques such as radio guided occult lesion localisation (ROLL), magnetic seeds, radiofrequency seeds localisation are a feasible and safe method of breast lesion localization as well and gaining popularity slowly. Faridpur Med. Coll. J. Jul 2019;14(2): 93-99

scholarly journals Accuracy of mammography and sonomammography and its correlation with histopathology in the detection of breast cancer

2021 ◽  
Vol 8 (2) ◽  
pp. 624
Author(s):  
Soundarya Yamakanamardi ◽  
Bharati V. Hiremath
Keyword(s):  
Breast Cancer ◽  
Malignant Tumors ◽  
Young Patients ◽  
Benign Tumors ◽  
Breast Lesions ◽  
Benign Lesions ◽  
Breast Lump ◽  
Palpable Breast ◽  
Detect Breast Cancer

Background: Mammography (MMG) plays a pivotal role in the early diagnosis of breast cancer (BC). However, it is sometimes difficult to use it to diagnose palpable breast lesions among young patients. Ultrasound can be used as an adjunct in differentiating cystic and solid masses. Studies evaluating the combination of MMG and sonomammography (SMG) as an adjunct to detect Breast cancer, are quite scarce in the literature. This study aimed to assess the accuracy of MMG and to comprehend the role of ultrasound as an adjunct to MMG for finding breast lesions.Methods: Women attending the outpatient department (OPD) with complaints of breast lump, or those undergoing MMG screening were included. All patients then subsequently underwent MMG, SMG and biopsy. MMG and SMG findings were then correlated with the histopathology results.Results: Irregular shape and calcifications (MMG) and hypoechoic pattern (SMG) were found to be significant features differentiating malignant from benign lesions. Calcifications in benign tumors were observed 5.05 times less frequently than in malignant tumors. MMG combined with SMG had a sensitivity of 90.4%, specificity of 82.4%, positive and negative predictive value of 95% and 67% respectively, along with an accuracy of 88.9% in differentiating benign from malignant masses.Conclusions: SMG used as an adjunct to MMG is a reliable modality, especially in detecting lesions that are not picked up on MMG, including intraductal papilloma and duct ectasia.

scholarly journals The Efficacy and Safety of Indocyanine green- hyaluronic acid mixture (LuminoMarkTM) for Localization in Patients with Non-palpable Breast Lesions: A Multi-center Open-label Parallel Phase-2 Clinical trial

2020 ◽  
Author(s):  
isaac kim ◽  
Hee Jun Choi ◽  
Jai Min Ryu ◽  
Se Kyung Lee ◽  
Jong Han Yu ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Hyaluronic Acid ◽  
Breast Lesion ◽  
Ultrasound Image ◽  
Test Group ◽  
Acid Mixture ◽  
Control Group ◽  
Breast Lesions ◽  
Efficacy And Safety ◽  
Palpable Breast

Abstract Backgrounds With increasing screening for breast cancer, non-palpable breast lesions are detected more frequently. A preoperative localization is very important for a minimal but accurate excision of a non-palpable breast lesion. The purpose of this study was to evaluate the efficacy and safety of indocyanine green(ICG)-hyaluronic acid mixture injection as a novel material for localization. Methods We performed prospective clinical trial with female patients who underwent surgery for non-palpable breast lesion. 44 patients were sequentially assigned to the control group(localization with activated charcoal), test group 1(ICG-hyaluronic acid mixture 0.1ml), or test group 2(ICG-hyaluronic acid mixture 0.2ml) by 1:1:1 ratio. Results Most were over 40 years old, and there were no differences between three groups in age distribution. According to the pathologic results, fibroadenoma accounted for the largest share (38.6%, 17/44) and malignancy accounted for 11.4% (5/44). The marking rate on both breast lesions and excised specimens was over 86% in all groups, and there was no difference. However, skin pigmentation was only in the control group and the accuracy of resection (the greatest length in cm of the excised specimen divided by the greatest length in cm on the pre-operation ultrasound image, the value closer to 1 meant resection as much as the size on ultrasound image) was different significantly. The average was 3.7(range 1.2-13.3) in control group and 2.2 (1.0-4.2) in test 1 group and 2.1(1.0-4.2) in test 2 group. Conclusion ICG-hyaluronic acid mixture injection was superior to activated charcoal for localization in patients with non-palpable breast lesions.

63 Breast Lesion Excision System for Diagnosis of Suspicious Non-palpable Breast Lesions: Does Thermal Tissue Damage Affect Diagnosis and Outcome?

2012 ◽  
Vol 48 ◽  
pp. S59
Author(s):  
W. Al-harethee ◽  
I. Papapanagiotou ◽  
V. Kalles ◽  
M. Matiatou ◽  
G. Georgeiou ◽  
...  
Keyword(s):  
Tissue Damage ◽  
Breast Lesion ◽  
Breast Lesions ◽  
Thermal Tissue Damage ◽  
Palpable Breast

scholarly journals FNAC OF BREAST LUMP WITH HISTOPATHOLOGICAL CORRELATION

2020 ◽  
pp. 1-2
Author(s):  
Vamshi Deepak Gudipati ◽  
Radhika Mucharla ◽  
Rammohan Peddi ◽  
K.Devender Reddy
Keyword(s):  
Excision Biopsy ◽  
Breast Lesions ◽  
Fibrocystic Disease ◽  
Breast Lump ◽  
Breast Masses ◽  
Medical College ◽  
Histopathological Correlation ◽  
Female Predominance ◽  
Palpable Breast ◽  
Breast Lumps

Introduction – FNAC has become increasingly popular in diagnosis of palpable breast masses. As it is sensitive, specific, economical and safe for screening of breast lesions Aims and objectives – to determine the histopathologic correlation of FNAC of breast lumps seen in department of pathology, Govt medical college, siddipet. Methods – 2 yrs. retrospective study if breast lumps , with all patients who had FNAC, with subsequent histopathological confirmation over the period July 2018 –July 2020. A total 232 cases included in which 187 cases are subjected to excision biopsy or mastectomy Results –2 yrs. under review (2018-2020) a total of 232 FNAC of breast lump were done. 197 (84.9%) benign cases, 13(11.6%) malignant cases, 8 (3.5%) inflammatory cases were diagnosed cytologically in which 98(42.24%) cases are fibro adenoma, 27(11.6%) are malignant cases and suspicious of malignancy, 26(11.2%) of gynecomastia, 23(9.91%) of fibrocystic disease with female predominance of 8:1 ratio (206:26). Age ranging from 9 yrs. – 85 yrs. with mean age of 47yrs ± 14.2 yrs. Conclusion – we therefore concluded that FNAC is a reliable diagnostic tool of breast lump in our hospital. FNAC guides the surgeons for further plan of management.

Validation and Modification of the Masood Scoring Index for the Diagnosis of Atypical Breast Lesions

2017 ◽  
Vol 61 (2) ◽  
pp. 111-116
Author(s):  
Shruti Semwal ◽  
Deepti Joshi ◽  
Akriti Khare ◽  
Garima Goel ◽  
Neelkamal Kapoor
Keyword(s):  
Sensitivity Analysis ◽  
Interobserver Variability ◽  
Breast Disease ◽  
Needle Aspiration ◽  
Breast Lesions ◽  
Breast Lump ◽  
Discrimination Ability ◽  
Palpable Breast ◽  
Scoring Index

Introduction: Cytological diagnosis of borderline breast lesions remains challenging, and interobserver variability exists in their interpretation. The Masood scoring index (MSI) has been proposed to help in the subgrouping of breast lesions using objective criteria. Aim: The aim of the present study was to assess the interobserver variability in the scoring of breast lesions according to MSI and to see the utility of a modified scheme for discriminating benign and atypical lesions. Study Design: Papanicolaou-stained smears (100 cases) that underwent fine needle aspiration for a palpable breast lump were independently evaluated by 2 observers, and the cases were categorized as per MSI. Percent agreement beyond chance score between both observers was calculated. Sensitivity analysis was performed by comparing the scores using models containing different parameters of MSI. Results: The agreement amongst the 2 observers for scores was found to be 0.88 and it was 69% for category-wise diagnosis. Sensitivity analysis showed that the model with only 3 cytological parameters (cell arrangement, pleomorphism, and nucleoli) had similar discrimination ability in the classification of breast disease as benign or atypical as the standard MSI model. Conclusion: Further simplified models of MSI should be tested for improved diagnostic accuracy and wider acceptability.

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