scholarly journals Efficacy and Safety of Argon Laser Trabeculoplasty in Lowering Intraocular Pressure as Adjunctive Treatment to Primary Open Angle Glaucoma

2019 ◽  
Vol 35 (1) ◽  
Author(s):  
Uzma Fasih, Erum Shahid Arshad Sheikh
Keyword(s):  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Argon Laser ◽  
Adjunctive Treatment ◽  
P Value ◽  
Open Angle ◽  
Argon Laser Trabeculoplasty ◽  
Laser Trabeculoplasty

Purpose: To assess efficacy and safety of argon laser trabeculoplasty (ALT) to lower intra ocular pressure (IOP) as adjunctive treatment in primary open angle glaucoma (POAG) patients. Study Design: Descriptive Cross Sectional. Place and Duration of Study: Ophthalmology Department, Abbassi Shaheed Hospital from May 2016 to August, 2017. Materials and Methods: Primary open glaucoma patients were selected from eye OPD. Patients with Inflammatory, angle closure, traumatic glaucoma were excluded. Pre laser and Post laser IOP was measured at 1st week then at 1, 3 and 6 months. Data was collected and analyzed on SPSS version 20. There were 114 patients Results: There were 69 (61%) male patients. Mean age of patients was 60.53 ± 10.71 years. Mean pre laser Intraocular pressure was 23.98 ± 10.01 mm Hg. Mean post laser IOP at one month was 15.6 ± 3.25 and at 6 months was 14.8 ± 3.28 mm Hg. Overall mean reduction of IOP was 9.18 mm Hg from baseline, with p value less than < 0.005. Pre laser 3 medications were used by 20 (18%) and 2 medications by 49 (43%). At 6 months follow-up 4 (3.5%) patients were on 3 medications and 31 (37%) were on 2 medications. It has a p value < 0.005. Drug free patients at 6 months follow-up were 37 (33%). Mild iritis was seen in 7 (6.14%) patients. Conclusion: Argon Laser Trabeculoplasty is effective and safe method to control IOP in POAG when used as an adjunct to medical therapy. It also decreases number of drugs used by patients. Key Words: Argon laser trabeculoplasty, intraocular pressure, primary open angle glaucoma.

Long-Term Follow-Up of Argon Laser Trabeculoplasty in Uncontrolled Primary Open-Angle Glaucoma

1990 ◽  
Vol 200 (4) ◽  
pp. 181-188 ◽  
Author(s):  
M. Amon ◽  
R. Menapace ◽  
U. Radax ◽  
A. Wedrich ◽  
Ch. Skorpik
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Argon Laser ◽  
Open Angle ◽  
Argon Laser Trabeculoplasty ◽  
Laser Trabeculoplasty ◽  
Long Term Follow Up

Comparative study of the efficacy of selective laser trabeculoplasty as initial or adjunctive treatment for primary open-angle glaucoma

2018 ◽  
Vol 29 (5) ◽  
pp. 524-531 ◽  
Author(s):  
Tomaž Gračner
Keyword(s):  
Intraocular Pressure ◽  
Standard Deviation ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Adjunctive Treatment ◽  
Open Angle ◽  
Selective Laser Trabeculoplasty ◽  
Laser Trabeculoplasty ◽  
The Mean

Aim: The aim of this study is to compare the efficacy of selective laser trabeculoplasty as initial or adjunctive treatment for primary open-angle glaucoma in a retrospective chart review. Methods: 28 eyes of 28 patients with newly diagnosed primary open-angle glaucoma, who formed the initial selective laser trabeculoplasty group, and 31 eyes of 31 patients suffering from medical uncontrolled primary open-angle glaucoma, who formed the adjunctive selective laser trabeculoplasty group, were treated with 180° selective laser trabeculoplasty. Patients were evaluated 1, 3, 6, 12, 18 and 24 months after treatment. Success was defined as an intraocular pressure lowering exceeding 20% of pretreatment intraocular pressure. Results: The mean follow-up time was 20.25 months (standard deviation = 8.1) for the initial selective laser trabeculoplasty group and 18.87 months (standard deviation = 8.8) for the adjunctive selective laser trabeculoplasty group (p = 0.538). No significant difference was found between the two groups for mean pretreatment intraocular pressure (21.43 mmHg (standard deviation = 3.2) vs 21.97 mmHg (standard deviation = 2.6); p = 0.766), for mean intraocular pressures and mean intraocular pressure reductions during whole follow-up period. At all follow-up visits, the mean percent intraocular pressure reduction was smaller in the adjunctive selective laser trabeculoplasty group than in the initial selective laser trabeculoplasty group, and such a difference was significant at 1 month (21.55% vs 26.79%; p = 0.039) and 24 months (24.82% vs 28.10%; p = 0.041). According to the Kaplan–Meier survival analysis, the 24-month success rate was 71.4% in the initial selective laser trabeculoplasty group and 71% in the adjunctive selective laser trabeculoplasty group, with no differences between the groups (p = 0.913). Conclusion: Selective laser trabeculoplasty is equally efficient in reducing intraocular pressure as initial or adjunctive treatment for primary open-angle glaucoma over 24 months.

scholarly journals Comparison of primary medicament therapy effects and primary argon laser trabeculoplasty on regulation of intraocular pressure and stability of perimetry findings in open angle glaucoma

2011 ◽  
Vol 68 (3) ◽  
pp. 225-230 ◽  
Author(s):  
Suncica Sreckovic ◽  
Mirjana Janicijevic-Petrovic ◽  
Nenad Petrovic ◽  
Miroslav Vukosavljevic
Keyword(s):  
Intraocular Pressure ◽  
Open Angle Glaucoma ◽  
Argon Laser ◽  
Mean Deviation ◽  
Open Angle ◽  
Argon Laser Trabeculoplasty ◽  
Laser Trabeculoplasty ◽  
Significant Difference ◽  
Index Value

Introduction/Aim. Argon Laser Trabeculoplasty (ALT) is a recognized method for reducing intraocular pressure (IOP) in patients with open angle glaucoma. The aim of this study was to compare the effects of primary medicament therapy and primary ALT on IOP regulation and stability of perimetry findings. Methods. A total of 50 eyes of 35 patients were treated with primary ALT while 50 eyes of 36 patients were treated with primary medicament therapy with 0.5% timolol with 20, 0.005% latanoprost 18 and with 2% dorzolamid 12 eyes. IOP was controled at 3 months, and the visual field at 6 months during a 30-month follow-up period. Results. In the first 24 months of follow-up there was no statistically significant difference in percentage of eyes with successfully regulated IOP. At 27th and 30th month, in the group primarily treated with medicaments a statistically significant higher percentage of successfully regulated IOP was observed in 98%, and 96% of the eyes, respectively, while in the group primarily treated with ALT the decline in the percentage of successfully regulated IOP was observed in 78% and 76% of the eyes, (?2-test, p = 0.002, p = 0.140). Both therapy groups showed stability of perimetry findings without statistically significant difference in the values of mean deviation (MD) index until the end of the monitoring period. The dynamics of change in MD index value showed a statistically significant greater decline in this parameter in subjects who had been primarily treated with medications during the last six months of follow-up, (two-factor analysis of variance with a repeated measurement, factor of time ? type of therapy, p = 0.030). Conclusion. Primary ALT equally successfully regulates IOP and restores stability of perimetry findings in patients with open angle glaucoma like the primary medicament therapy.

scholarly journals Efficacy of Microwave Pulse Diode Laser and Argon Laser Trabeculoplasty in Patients with Primary Open Angle Glaucoma

2020 ◽  
Vol 36 (3) ◽  
Author(s):  
Asma Shams ◽  
Narain Das ◽  
Noman Rashid ◽  
M. Nasir Bhatti ◽  
Beenish Khan ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Diode Laser ◽  
Microwave Pulse ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Argon Laser ◽  
Open Angle ◽  
Argon Laser Trabeculoplasty ◽  
Laser Trabeculoplasty ◽  
Group B

Purpose:  To compare the efficacy of the microwave pulse diode laser and argon laser trabeculoplasty in primary open angle glaucoma. Study Design:  Quasi experimental study. Place and Duration of Study:  Shaheed Mohtarma Benazir Bhutto Medical College Lyari and Sindh Government Lyari General Hospital, Karachi, from October, 2017 to March, 2018. Material and Methods:  One hundred and sixty patients, between 42 to 61 years with visual acuity of perception of light to 6/36 were enrolled. Patients diagnosed with POAG were included and patients with intraocular pressure of more than 40 mm Hg, previous glaucoma surgery or laser treatment and narrow angle on gonioscopy were excluded. Ophthalmic examination included visual acuity, slit lamp examination, fundus examination and visual field status using Humphrey perimeter. Patients were divided into two groups. Group A received microwave pulse diode laser (810) and Group B received argon laser trabeculoplasty. Average follow up period was 6 months. Success was assessed objectively by measuring intra ocular pressure and subjectively by visual acuity. Results:  The average time-period for each procedure was 15 ± 5 minutes. In Group A, mean IOP at first week, first month, third month and sixth month was 20.79, 16.34, 16.21and 16.09 mm Hg respectively. While in Group B, IOP at first week, first, third and sixth month was 16.52, 15.76, 13.62, and 12.54 mm Hg at (P < 0.001 in both groups). Conclusion:  Both microwave pulse diode laser and argon laser trabeculoplasty are effective in lowering intra ocular pressures in patients with primary open angle glaucoma.

Is Argon Laser Trabeculoplasty Equivalent to Topical Medication as an Initial Treatment for Primary Open-Angle Glaucoma?

2020 ◽  
pp. 61-66
Author(s):  
Alan D. Penman ◽  
Kimberly W. Crowder ◽  
William M. Watkins
Keyword(s):  
Initial Treatment ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Argon Laser ◽  
Controlled Clinical Trial ◽  
Open Angle ◽  
Safe Alternative ◽  
Topical Medication ◽  
Argon Laser Trabeculoplasty ◽  
Laser Trabeculoplasty

The Glaucoma Laser Trial (GLT) was a randomized, single-blind, controlled clinical trial comparing the efficacy and safety of argon laser trabeculoplasty (ALT) to treatment with topical medication for controlling intraocular pressure (IOP) in patients with newly diagnosed, previously untreated, primary open-angle glaucoma (POAG). The study showed that initial treatment of POAG with ALT is an efficacious and safe alternative to medication therapy, particularly in patients where medical therapy is contraindicated or poor compliance is suspected. The initial use of ALT in the short term has the benefit of reducing the nuisance, inconvenience, and systemic side effects of the topical glaucoma medication alternatives.

scholarly journals Complex use of energetic surgery in treatment of patients with primary open-angle glaucoma and cataract on the background of pseudoexfoliative syndrome

2021 ◽  
Vol 14 (3) ◽  
pp. 25-34
Author(s):  
Benta G. Dzhashi ◽  
Sergei V. Balalin
Keyword(s):  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Hypotensive Effect ◽  
Open Angle ◽  
Selective Laser Trabeculoplasty ◽  
Visual Functions ◽  
Incipient Stage ◽  
Laser Trabeculoplasty

BACKGROUND: Glaucoma remains one of the current problems of modern ophthalmology. The combination of glaucoma and cataract is observed in 1738.6% of cases, and glaucoma with pseudoexfoliative syndrome in 2050% of primary open-angle glaucoma cases. AIM: The aim of this work is to develop an effective and safe technology of complex energetic surgical treatment of the incipient primary open-angle glaucoma stage and cataract on the background of pseudoexfoliation syndrome on the basis of modified laser, hydrodynamic and ultrasound methods use. MATERIALS AND METHODS: 187 patients (187 eyes) with the incipient stage of primary open-angle glaucoma, cataract and pseudoexfoliation syndrome were examined. In the main group (111 eyes), selective laser trabeculoplasty followed by femtosecond laser-assisted cataract surgery with hydrodynamic trabeculocleaning was performed. Patients in the control group (76 eyes), after selective laser trabeculoplasty, underwent phacoemulsification according to the standard technique. RESULTS: The developed technology allowed to reach the hypotensive effect in 35.2% (t=23.0; р 0.001) of baseline intraocular pressure values, of individual intraocular pressure level without adding IOP-lowering medications in 27% of cases, stabilization of visual functions and morphometric indices of the optic disc during 2 years of follow-up in 97.3% of cases unlike the selective laser trabeculoplasty with subsequent phacoemulsification (21.2, 5.3 and 81.6% respectively). The patients of the main group had significantly lower energy expenditure during the stage of phacoemulsification, a lower percentage of postoperative inflammatory reaction was noted, and a persistent hypotensive effect with stabilization of visual functions was achieved based on the results of a two-year follow-up. CONCLUSIONS: Femtosecond laser-assisted phacoemulsification, performed as part of complex treatment in patients with cataract and incipient stage of primary open-angle glaucoma, is a sparing method that minimizes surgical trauma and achieves a persistent hypotensive effect, reduces intraocular pressure to an individual level and stabilizes visual functions in 97.3% of cases.

Argon Laser Trabeculoplasty in Black and White Patients with Primary Open-angle Glaucoma

Ophthalmology ◽  
1986 ◽  
Vol 93 (6) ◽  
pp. 811-816 ◽  
Author(s):  
Theodore Krupin ◽  
Randall Patkin ◽  
Fred K. Kurata ◽  
Kim I. Bishop ◽  
Edwin U. Keates ◽  
...  
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Argon Laser ◽  
Open Angle ◽  
Argon Laser Trabeculoplasty ◽  
Black And White ◽  
Laser Trabeculoplasty ◽  
White Patients
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