scholarly journals PRIMARY MALIGNANT MELANOMA UTERINE CERVIX

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Asghar H Asghar ◽  
Sadia Rizvi ◽  
Akhtar Ahmed ◽  
Ahmed N Abbasi ◽  
Abid Jamal ◽  
...  

A 40-year-old premenopausal female presented with foul-smelling per vaginal discharge for 3 months. Diagnostic work revealed a locally advanced primary malignant melanoma of uterine cervix. The patient declined pelvic surgery and was treated with Dacarbazine. Malignant melanoma is a rare tumour of skin and has been ranked in the top ve cancers of Australia and Sweden. It is a tumour of melanocytes which forms melanin pigment in the skin. In men, the most common site is trunk while in females common site is limbs. However, melanoma can arise from mucosal surfaces where the melanocytes are present. Most common mucosal sites are head and neck followed by female genital tract. Key words: Cervix, dacarbazine, malignant melanoma 

Medicine ◽  
2019 ◽  
Vol 98 (30) ◽  
pp. e16366 ◽  
Author(s):  
Yingxin Pang ◽  
Hang Yuan ◽  
Anji Ren ◽  
Shiqian Zhang ◽  
Peishu Liu

1999 ◽  
Vol 18 (3) ◽  
pp. 265-273 ◽  
Author(s):  
Katherine C. Clark ◽  
William R. Butz ◽  
Marc R. Hapke

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Tomoko Noguchi ◽  
Nami Ota ◽  
Yasushi Mabuchi ◽  
Shigetaka Yagi ◽  
Sawako Minami ◽  
...  

Malignant melanoma (MM) in the female genital tract accounts for less than 2% of all melanomas, and the vast majority associated occur in the vulva and vagina. Primary MM of the uterine cervix is extremely rare and its prognosis is very poor. We report a case of primary MM of the cervix with dissemination throughout the vaginal wall. A 66-year-old woman presented with postmenopausal bleeding. Gynecologic examination demonstrated a 2 cm polypoid blackish-pigmented tumor on the cervix with multiple small blackish-pigmented lesions throughout the vaginal wall. Cervical Pap smear cytology showed malignant melanoma. MRI and PET/CT did not detect any distant or lymph node metastases. She underwent radical hysterectomy, pelvic lymphadenectomy, and total vaginectomy. The pathological diagnosis was FIGO stage IIIA primary cervical MM. She received adjuvant chemotherapy with 6 courses of dacarbazine, but 6 months later, multiple lung metastases were detected. Despite 4 courses of anti-PD-1 antibody (nivolumab) treatment, she died of the disease 13 months after surgery.


2018 ◽  
Vol 34 (4) ◽  
pp. 209-213 ◽  
Author(s):  
Anastasios Tranoulis ◽  
Alexandros Laios ◽  
Sharika Munot ◽  
George Theophilou ◽  
Darshana Pathak ◽  
...  

1998 ◽  
Vol 5 (4) ◽  
pp. 159-160 ◽  
Author(s):  
Guilherme Cantuaria ◽  
Roberto Angioli ◽  
Ari Fernandez-Abril ◽  
M. Penalver

1988 ◽  
Vol 39 (3) ◽  
pp. 336-338 ◽  
Author(s):  
O.J. Owens ◽  
K. Pollard ◽  
G.G. Khoury ◽  
J.E.D. Dyson ◽  
G.J. Jarvis ◽  
...  

Author(s):  
Goter Doke ◽  
Shyam Tsering ◽  
Hage Nobin ◽  
Dacto Gara

Primary malignant melanoma of the uterine cervix is a rare neoplasm and the overall prognosis of patients with this disease is very poor. Herein, authors report a case of 45-year-old woman who presented with vaginal bleeding for one months and examination showed an exophytic, 6 cm polypoid blackish-pigmented tumor on the cervix involving vaginal fornix. She underwent abdominal radical hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy and further received adjuvant concurrent chemo-radiation with cisplatin (CDDP) and temozolamide but died 7 months after surgery.


2013 ◽  
Vol 2013 (jun03 1) ◽  
pp. bcr2013010042-bcr2013010042 ◽  
Author(s):  
N. Singh ◽  
R. Tripathi ◽  
Y. M. Mala

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