scholarly journals Evaluation of efficiency and safety of apicold mint nose spray for allergic rhinitis

2021 ◽  
pp. 82-86
Author(s):  
Anatoly L. Kosakovsky
Keyword(s):  
Allergic Rhinitis ◽  
Clinical Study ◽  
Nasal Spray ◽  
Topical Corticosteroids ◽  
Complex Therapy

Introduction: Allergic rhinitis affects 10 to 40% of the population, and among children the incidence is 2-25%. Aim: Evaluation of the effectiveness and safety of "Apicold Mint" nasal spray in children and adults with allergic rhinitis. Material and methods: The effect of "Apicold Mint" Nasal Spray (manufactured by APIPHARMA doo) was studied in 45 patients with allergic rhinitis. The clinical study involved 21 (47%) children aged 4 to 18 years and 24 (53%) adults. Results and discussion: The use of the drug "Apicold Mint" nasal spray helps to reduce the symptoms of allergic rhinitis and eliminates the feeling of dryness, which often occurs with the use of topical corticosteroids and decongestants. In addition, the use of the drug "Apicold Mint" nasal spray significantly reduced the need for vasoconstrictor drops, which is also positive in the treatment of patients with allergic rhinitis. Conclusion: Appointment of the drug "Apicold Mint" nasal spray in the complex therapy of allergic rhinitis contributes to a faster reduction of symptoms and increases the effectiveness of local drugs.

scholarly journals A new approach to the treatment of allergic rhinitis

2021 ◽  
pp. 62-72
Author(s):  
Sergey M. Pukhlik ◽  
Iryna V. Diedykova ◽  
Viktor K. Bohdanov
Keyword(s):  
Allergic Rhinitis ◽  
Clinical Study ◽  
Ganoderma Lucidum ◽  
Scientific Literature ◽  
New Approach ◽  
Natural Origin ◽  
Complex Therapy ◽  
Receptor Blockers ◽  
Leukotriene Receptor ◽  
And Control

The growth of allergic morbidity, as well as certain limitations in traditional therapy, sets the task of finding new means and methods of treating this pathology. Antihistamines and leukotriene receptor blockers traditionally belong to drugs that affect the symptoms of inflammation and control the course of diseases of allergic genesis. Substances of natural origin, whose effectiveness and safety have been proven for centuries, have similar properties. The article analyzes the data of the available scientific literature concerning the experience of using macromycetes of the genus Ganoderma in clinical practice. Our clinical study showed that the inclusion of the drug "Astmagan", based on Ganoderma lucidum, in the complex therapy of seasonal and year-round allergic rhinitis, increased the effectiveness of treatment. The authors consider that this will allow a more differentiated approach to the choice of the optimal scheme of complex therapy for allergic rhinitis.

scholarly journals Comparative Nasal Airflow with Loratadine-Pseudoephedrine and Fluticasone Nasal Spray for Allergic Rhinitis

2021 ◽  
Author(s):  
Charlene C. Ng ◽  
Daniel Romaikin ◽  
Lisa M. Steacy ◽  
David A. Stevens ◽  
Terry J. Walker ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Spray ◽  
Nasal Airflow

scholarly journals The Effect of Broccoli Sprout Extract on Seasonal Grass Pollen-Induced Allergic Rhinitis

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1337
Author(s):  
Joseph Yusin ◽  
Vivian Wang ◽  
Susanne M. Henning ◽  
Jieping Yang ◽  
Chi-Hong Tseng ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Spray ◽  
Placebo Tablet ◽  
Group 4 ◽  
Cytokine Levels ◽  
Before And After ◽  
Group 3 ◽  
Nasal Steroid ◽  
Group 2 ◽  
Broccoli Sprout

Patients exposed to pollutants are more likely to suffer from allergic rhinitis and may benefit from antioxidant treatment. Our study determined if patients diagnosed with grass-induced allergic rhinitis could benefit from broccoli sprout extract (BSE) supplementation. In total, 47 patients were confirmed with grass-induced allergic rhinitis and randomized to one of four groups: group 1 (nasal steroid spray + BSE), group 2 (nasal steroid spray + placebo tablet), group 3 (saline nasal spray + BSE) and group 4 (saline nasal spray + placebo tablet). Peak Nasal Inspiratory Flow (PNIF), Total Nasal Symptoms Scores (TNSS) and nasal mucus cytokine levels were analyzed in samples collected before and after the 3-week intervention. Comparing before and after the intervention, PNIF improved significantly when comparing Groups 1 and 2, vs. placebo, at various time points (p ≤ 0.05 at 5, 15, 60 and 240 min) following nasal challenge, while TNSS was only statistically significant at 5 (p = 0.03), 15 (p = 0.057) and 30 (p = 0.05) minutes. There were no statistically significant differences in various cytokine markers before and after the intervention. Combining nasal corticosteroid with BSE led to the most significant improvement in objective measures.

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