scholarly journals A new approach to the treatment of allergic rhinitis

2021 ◽  
pp. 62-72
Author(s):  
Sergey M. Pukhlik ◽  
Iryna V. Diedykova ◽  
Viktor K. Bohdanov
Keyword(s):  
Allergic Rhinitis ◽  
Clinical Study ◽  
Ganoderma Lucidum ◽  
Scientific Literature ◽  
New Approach ◽  
Natural Origin ◽  
Complex Therapy ◽  
Receptor Blockers ◽  
Leukotriene Receptor ◽  
And Control

The growth of allergic morbidity, as well as certain limitations in traditional therapy, sets the task of finding new means and methods of treating this pathology. Antihistamines and leukotriene receptor blockers traditionally belong to drugs that affect the symptoms of inflammation and control the course of diseases of allergic genesis. Substances of natural origin, whose effectiveness and safety have been proven for centuries, have similar properties. The article analyzes the data of the available scientific literature concerning the experience of using macromycetes of the genus Ganoderma in clinical practice. Our clinical study showed that the inclusion of the drug "Astmagan", based on Ganoderma lucidum, in the complex therapy of seasonal and year-round allergic rhinitis, increased the effectiveness of treatment. The authors consider that this will allow a more differentiated approach to the choice of the optimal scheme of complex therapy for allergic rhinitis.

scholarly journals Evaluation of efficiency and safety of apicold mint nose spray for allergic rhinitis

2021 ◽  
pp. 82-86
Author(s):  
Anatoly L. Kosakovsky
Keyword(s):  
Allergic Rhinitis ◽  
Clinical Study ◽  
Nasal Spray ◽  
Topical Corticosteroids ◽  
Complex Therapy

Introduction: Allergic rhinitis affects 10 to 40% of the population, and among children the incidence is 2-25%. Aim: Evaluation of the effectiveness and safety of "Apicold Mint" nasal spray in children and adults with allergic rhinitis. Material and methods: The effect of "Apicold Mint" Nasal Spray (manufactured by APIPHARMA doo) was studied in 45 patients with allergic rhinitis. The clinical study involved 21 (47%) children aged 4 to 18 years and 24 (53%) adults. Results and discussion: The use of the drug "Apicold Mint" nasal spray helps to reduce the symptoms of allergic rhinitis and eliminates the feeling of dryness, which often occurs with the use of topical corticosteroids and decongestants. In addition, the use of the drug "Apicold Mint" nasal spray significantly reduced the need for vasoconstrictor drops, which is also positive in the treatment of patients with allergic rhinitis. Conclusion: Appointment of the drug "Apicold Mint" nasal spray in the complex therapy of allergic rhinitis contributes to a faster reduction of symptoms and increases the effectiveness of local drugs.

Effects of Virgin Coconut Oil as Adjunct Therapy in the Treatment of Allergic Rhinitis

2016 ◽  
Vol 1 (1) ◽  
pp. 22
Author(s):  
Nazli Zainuddin ◽  
Nurul Azira Mohd Shah ◽  
Rosdan Salim
Keyword(s):  
Allergic Rhinitis ◽  
Side Effects ◽  
Coconut Oil ◽  
Test Group ◽  
Nasal Symptom ◽  
Control Group ◽  
Virgin Coconut Oil ◽  
Control Groups ◽  
Significant Difference ◽  
And Control

Introduction: The role of virgin coconut oil in the treatment of allergic rhinitis is controversial. Thus, the aim of the present study is to determine the effects of virgin coconut oil ingestion, in addition to standard medications, on allergic rhinitis. We also studied the side effects of consumption of virgin coconut oil. Methods: Fifty two subjects were equally divided into test and control groups. All subjects received a daily dose of 10mg of loratadine for 28 days. The test group was given 10ml of virgin coconut oil three times a day in addition to loratadine. The symptoms of allergic rhinitis were scored at the beginning and end of the study. Results:, the symptom score were divided into nasal and non-nasal symptom scores. Sneezing score showed a significant difference, however the score was more in control group than test group, indicating that improvement in symptom was more in control group. The rest of the nasal symptom and non-nasal symptom score showed no significant difference between test and control groups. Approximately 58% of the test subjects developed side effects from consumption of virgin coconut oil, mainly gastrointestinal side effects. Conclusion: In the present study, ingestion of virgin coconut oil does not improve the overall and individual symptoms of allergic rhinitis, furthermore it has side effects.

On-Surface Radical Oligomerisation: A New Approach to STM Tip-Induced Reactions

2018 ◽  
Author(s):  
Gaolei Zhan ◽  
Younes Makoudi ◽  
Judicael Jeannoutot ◽  
Simon Lamare ◽  
Michel Féron ◽  
...  
Keyword(s):  
Sample Surface ◽  
Scanning Tunnelling Microscope ◽  
Transfer Event ◽  
New Approach ◽  
The Past ◽  
Organic Nanostructures ◽  
Scanning Tunnelling ◽  
New Strategy ◽  
Surface Fabrication ◽  
And Control

Over the past decade, on-surface fabrication of organic nanostructures has been widely investigated for the development of molecular electronic devices, nanomachines, and new materials. Here, we introduce a new strategy to obtain alkyl oligomers in a controlled manner using on-surface radical oligomerisations that are triggered by the electrons/holes between the sample surface and the tip of a scanning tunnelling microscope. The resulting radical-mediated mechanism is substantiated by a detailed theoretical study. This electron transfer event only occurs when <i>V</i><sub>s</sub> < -3 V or <i>V</i><sub>s</sub> > + 3 V and allows access to reactive radical species under exceptionally mild conditions. This transfer can effectively ‘switch on’ a sequence leading to formation of oligomers of defined size distribution due to the on-surface confinement of reactive species. Our approach enables new ways to initiate and control radical oligomerisations with tunnelling electrons, leading to molecularly precise nanofabrication.

scholarly journals Effectiveness of a Selective Etching Technique in Reducing White Spots Formation around Lingual Brackets: A Prospective Cohort Clinical Study

Coatings ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 572
Author(s):  
Domenico Dalessandri ◽  
Marino Bindi ◽  
Francesca Massetti ◽  
Gaetano Isola ◽  
Marco Migliorati ◽  
...  
Keyword(s):  
Clinical Study ◽  
Difficulty Level ◽  
Prospective Clinical Study ◽  
White Spot Lesions ◽  
Etching Technique ◽  
White Spots ◽  
Accumulation Index ◽  
One Year ◽  
Lingual Brackets ◽  
And Control

The risk of developing white spot lesions (WSLs) after orthodontic treatment with lingual brackets is generally considered lower than with labial ones, even if plaque accumulation is frequently higher due to the increased difficulty level in oral hygiene maintenance. In this prospective clinical study, selective enamel etching technique effectiveness in reducing plaque accumulation and WSLs was tested. Thirty patients were bonded with a split-mouth approach: two randomly selected opposite quadrants were used as the test sides, using customized plastic etching guides, and the other two as control sides, applying traditional direct etching methods. The plaque presence around the braces was recorded after 1, 3, 6, and 12 months according to a lingual plaque accumulation index (LPAI), as was the presence of WSLs. PAI measured values were significantly higher in the control sides during the observation period. Test and control sides differed significantly for new WSL onset only after 12 months of treatment. Therefore, the present research demonstrated that this guided enamel etching technique allowed for significant reduction in plaque accumulation around the lingual brackets and reduced onset of white spots after one year of treatment.

A Clinical Study to Evaluate the Role of Vitamin D3 in Allergic Rhinitis

2022 ◽  
Author(s):  
Gopika Kalsotra ◽  
Aditiya Saraf ◽  
Apurva Raina ◽  
Parmod Kalsotra ◽  
Rupali Sharma ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Clinical Study ◽  
Vitamin D3

scholarly journals Is suicidal ideation associated with allergic asthma and allergic rhinitis?

2018 ◽  
Vol 44 (1) ◽  
pp. 31-35 ◽  
Author(s):  
Martín Bedolla-Barajas ◽  
Norma Angélica Pulido-Guillén ◽  
Bolívar Vivar-Aburto ◽  
Jaime Morales-Romero ◽  
José Raúl Ortiz-Peregrina ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Suicidal Ideation ◽  
Allergic Asthma ◽  
Allergic Diseases ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Control Group ◽  
Healthy Controls ◽  
Cross Sectional ◽  
And Control

ABSTRACT Objective: To investigate whether there is an association between suicidal ideation (SI) and allergic diseases in adults. Methods: This was a comparative cross-sectional study involving individuals ranging from 20 to 50 years of age recruited from a university hospital in the city of Guadalajara, Mexico. We included patients with a confirmed diagnosis of allergic asthma, those with a confirmed diagnosis of allergic rhinitis, and healthy controls. All subjects completed the Beck Depression Inventory-II (BDI-II), which includes an item that evaluates the presence of suicidal thoughts or desires within the last two weeks, in order to identify SI. Results: The sample comprised 115 patients with allergic asthma, 111 patients with allergic rhinitis, and 96 healthy controls. The number of individuals identified with SI in the three groups were, respectively, 17 (14.8%), 13 (11.7%), and 8 (8.3%). Regarding the presence of SI, no statistically significant association was found in the allergic asthma group (OR = 1.98; 95% CI: 0.78-4.64; p = 0.154) or in the allergic rhinitis group (OR = 1.46; 95% CI: 0.58-3.68; p = 0.424) when they were compared with the control group. However, the presence of depression was associated with SI in the three groups: allergic asthma (OR = 12.36; 95% CI: 2.67-57.15; p = 0.001); allergic rhinitis (OR = 6.20; 95% CI: 1.66-23.14; p = 0.006); and control (OR = 21.0; 95% CI: 3.75-117.36; p < 0,001). Conclusions: In comparison with the control group, no association was found between SI and the groups with allergic diseases. In contrast, there was association between SI and depression in the three groups.

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