scholarly journals Medical management of metabolic and cardiovascular complications after liver transplantation

2020 ◽  
Vol 26 (18) ◽  
pp. 2138-2154
Author(s):  
Chiara Becchetti ◽  
Melisa Dirchwolf ◽  
Vanessa Banz ◽  
Jean-François Dufour
2017 ◽  
Vol 22 (2) ◽  
pp. 111-121 ◽  
Author(s):  
Christopher L. Wray

Liver transplantation (LT) is a unique surgical procedure that has major hemodynamic and cardiovascular implications. Recently, there has been significant interest focused on cardiovascular issues that affect LT patients in all phases of the perioperative period. The preoperative cardiac evaluation is a major step in the selection of LT candidates. LT candidates are aging in concordance with the general population; cardiovascular disease and their risk factors are highly associated with older age. Underlying cardiovascular disease has the potential to affect outcomes in LT patients and has a major impact on candidate selection. The prolonged hemodynamic and metabolic instability during LT may contribute to adverse outcomes, especially in patients with underlying cardiovascular disease. Cardiovascular events are not unusual during LT; transplant anesthesiologists must be prepared for these events. Advanced cardiovascular monitoring techniques and treatment modalities are now routinely used during LT. Postoperative cardiovascular complications are common in both the early and late posttransplant periods. The impact of cardiac complications on posttransplant mortality is well recognized. Emerging knowledge regarding cardiovascular disease in LT patients and its impact on posttransplant outcomes will have an important role in guiding the future perioperative management of LT patients.


2012 ◽  
Vol 142 (5) ◽  
pp. S-1005
Author(s):  
Mazen Albeldawi ◽  
Vedant Gupta ◽  
Gurshawn Singh ◽  
Paresh P. Mehta ◽  
Rocio Lopez ◽  
...  

1996 ◽  
Vol 6 (3) ◽  
pp. 139-144
Author(s):  
Lora Schwartz ◽  
Jo Augustine ◽  
Joann Raymer ◽  
Vincent Canzanello ◽  
Sandra Taler ◽  
...  

Hypertension develops soon after organ transplantation using cyclosporine- or FK506-based immunosuppression. Sustained rises in blood pressure require intervention to reduce the risk of intracranial bleeding and other cardiovascular complications. Antihypertensive treatment is complicated by reduced renal function and potential interference with absorption and/or metabolism of cyclosporine or FK506. To manage early and long-term hypertension related to immunosuppression with cyclosporine or FK506 and prednisone following orthotopic liver transplantation, a comprehensive nurse-managed hypertension clinic was developed. Blood pressure, heart rate, and antihypertensive and immunosuppressive regimens were evaluated according to a standard protocol at 1, 4, 12, 24, and 36 months after orthotopic liver transplantation. Data indicate that posttransplantation hypertension develops within the first months after orthotopic liver transplantation and persists indefinitely. If comprehensively managed by the hypertension nurse-clinician, the percentage of controlled hypertension patients can increase over time.


2021 ◽  
Vol 116 (1) ◽  
pp. S533-S534
Author(s):  
Taseen Syed ◽  
Gurukripa Kowlgi ◽  
Anna Tomdio ◽  
Steve Shen ◽  
Samarth Patel ◽  
...  

2009 ◽  
Vol 104 ◽  
pp. S134
Author(s):  
Tarun Chugh ◽  
Harshad Amin ◽  
Kaushang Gandhi ◽  
Harit Desai ◽  
Hoang Lai ◽  
...  

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