Estimation of Interferon Gamma and Zinc Concentration in Serum of Cutaneous Leishmaniasis Patients in Tikrit City

Author(s):  
Ghaydaa Abdulwahed Awadh Al-Tikrity
2014 ◽  
Vol 7 (6) ◽  
Author(s):  
Yahya Maroufi ◽  
Fatemeh Ghaffarifar ◽  
Abdolhosein Dalimi ◽  
Zohreh Sharifi

Dermatology ◽  
1996 ◽  
Vol 192 (1) ◽  
pp. 56-60 ◽  
Author(s):  
G. Kolde ◽  
T. Luger ◽  
C. Sorg ◽  
C.S. Sunderkötter

2020 ◽  
pp. 970-977 ◽  
Author(s):  
Reem Aladdin Jameel ◽  
B. N. Al-Qadhi

Cutaneous leishmaniasis (CL) is one of the most prevalent cutaneous parasitic protozoan infections in Iraq; characterized by a chronic infection and granulomatous disease that invades the skin. Type 1 immune was predominates in CL patients with exacerbated production of pro-inflammatory cytokine, therefore this study aimed to evaluate serum level of interferon gamma (IFN-γ) and monokine induce by interferon gamma (MIG/CXCl9) as a useful markers of disease development in patients during different stage of infection (<1 month .. early , 1-6 month.. chronic and >6 months.. late). The result showed that there was an early effort to eliminate the parasite proliferation which illustrated by a high significant increase of both IFN-γ and MIG during the early stage of infection, but this response was down-regulated during the chronic stage of infection, which observed by low levels of both studied cytokine and monokine, nevertheless this down-regulation was transient where the levels to increase returns during the late stage of infection. The evaluation of IFN-γ and MIG considered as a biological markers of disease activity in each stage of infection.


1997 ◽  
Vol 27 (11) ◽  
pp. 1254-1260 ◽  
Author(s):  
M. O. HOEKSTRA ◽  
Y. HOEKSTRA ◽  
D. DE REUS ◽  
B. RUTGERS ◽  
J. GERRITSEN ◽  
...  

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