Diels–Alder reactions of myrcene using intensified continuous-flow reactors
2017 ◽
Vol 13
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pp. 120-126
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Keyword(s):
Scale Up
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This work describes the Diels–Alder reaction of the naturally occurring substituted butadiene, myrcene, with a range of different naturally occurring and synthetic dienophiles. The synthesis of the Diels–Alder adduct from myrcene and acrylic acid, containing surfactant properties, was scaled-up in a plate-type continuous-flow reactor with a volume of 105 mL to a throughput of 2.79 kg of the final product per day. This continuous-flow approach provides a facile alternative scale-up route to conventional batch processing, and it helps to intensify the synthesis protocol by applying higher reaction temperatures and shorter reaction times.
2018 ◽
Vol 14
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pp. 318-324
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Keyword(s):
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2011 ◽
Vol 2012
(1)
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pp. 47-52
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Keyword(s):
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1991 ◽
Vol 23
(4-6)
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pp. 1001-1010
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2019 ◽
Vol 4
(2)
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pp. 362-367
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Keyword(s):