Synthesis of ribavirin 2’-Me-C-nucleoside analogues

Beilstein Journal of Organic Chemistry ◽

10.3762/bjoc.13.74 ◽

2017 ◽

Vol 13 ◽

pp. 755-761 ◽

Author(s):

Fanny Cosson ◽

Aline Faroux ◽

Jean-Pierre Baltaze ◽

Jonathan Farjon ◽

Régis Guillot ◽

...

Keyword(s):

Carbon Atom ◽

Nucleoside Analogues ◽

Quaternary Carbon ◽

Quaternary Carbon Atom ◽

Synthetic Pathway ◽

An efficient synthetic pathway leading to two carbonated analogues of ribavirin is described. The key-steps in the synthesis of these ribosyltriazoles bearing a quaternary carbon atom in the 2’-position are an indium-mediated alkynylation and a 1,3-dipolar cyclization.

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Three 2-oxazolinyl rings on one quaternary carbon atom: preparation of a novel tripodal tris(oxazolinyl) ligand and the tetrameric molecular structure of its CuI complex

Chemical Communications ◽

10.1039/b202846h ◽

2002 ◽

pp. 1286-1287 ◽

Author(s):

Stéphane Bellemin-Laponnaz ◽

Lutz H. Gade

Keyword(s):

Molecular Structure ◽

Carbon Atom ◽

Quaternary Carbon ◽

Quaternary Carbon Atom

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Stable Cyclic (Alkyl)(amino)carbenes as Rigid or Flexible, Bulky, Electron-Rich Ligands for Transition-Metal Catalysts: A Quaternary Carbon Atom Makes the Difference.

10.1002/chin.200601110 ◽

2006 ◽

Vol 37 (1) ◽

Author(s):

Vincent Lavallo ◽

Yves Canac ◽

Carsten Praesang ◽

Bruno Donnadieu ◽

Guy Bertrand

Keyword(s):

Carbon Atom ◽

Transition Metal ◽

Metal Catalysts ◽

Transition Metal Catalysts ◽

Quaternary Carbon ◽

Quaternary Carbon Atom ◽

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ChemInform Abstract: ALKYL GROUPS MIGRATION FROM TETRAALKYLSILANES, -GERMANES, AND -STANNANES TO CARBENIUM IONS, EFFECTED BY LEWIS ACIDS: A NOVEL METHOD FOR SYNTHESIZING HYDROCARBONS WITH A QUATERNARY CARBON ATOM

Chemischer Informationsdienst ◽

10.1002/chin.198050141 ◽

1980 ◽

Vol 11 (50) ◽

Author(s):

Z. N. PARNES ◽

G. I. BOLESTOVA ◽

I. S. AKHREM ◽

M. E. VOL'PIN ◽

D. N. KURSANOV

Keyword(s):

Carbon Atom ◽

Lewis Acids ◽

Quaternary Carbon ◽

Quaternary Carbon Atom ◽

Carbenium Ions ◽

Alkyl Groups ◽

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165. Long-chain acids containing a quaternary carbon atom. Part II

Journal of the Chemical Society (Resumed) ◽

10.1039/jr9430000615 ◽

1943 ◽

pp. 615 ◽

Author(s):

N. Polgar ◽

Robert Robinson

Keyword(s):

Carbon Atom ◽

Quaternary Carbon ◽

Quaternary Carbon Atom ◽

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Reversible aryl migrations in metallated ureas: controlled inversion of configuration at a quaternary carbon atom

Chemical Communications ◽

10.1039/c2cc38704b ◽

2013 ◽

Vol 49 (15) ◽

pp. 1548 ◽

Author(s):

Daniel J. Tetlow ◽

Mark A. Vincent ◽

Ian H. Hillier ◽

Jonathan Clayden

Keyword(s):

Carbon Atom ◽

Quaternary Carbon ◽

Quaternary Carbon Atom

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Novel Routes to Branchd-chain and Amino-sugars from Levoglucosenone, a Chiral Synthon Available from Cellulose. Structural Determination at Quaternary Carbon Atom by X-Ray Diffraction

Heterocycles ◽

10.3987/r-1986-04-0931 ◽

1986 ◽

Vol 24 (4) ◽

pp. 931 ◽

Author(s):

Jacques Gelas ◽

Yvonne Gelas-Mialhe ◽

Danielle Avenel ◽

Rachid Brahmi ◽

H四熟e Gillier-Pandraud

Keyword(s):

Carbon Atom ◽

Amino Sugars ◽

Structural Determination ◽

Quaternary Carbon ◽

X Ray Diffraction ◽

Quaternary Carbon Atom ◽

X Ray ◽

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88. Long-chain acids containing a quaternary carbon atom. Part I

Journal of the Chemical Society (Resumed) ◽

10.1039/jr9420000488 ◽

1942 ◽

pp. 488 ◽

Author(s):

A. J. Birch ◽

Robert Robinson

Keyword(s):

Carbon Atom ◽

Quaternary Carbon ◽

Quaternary Carbon Atom ◽

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Derivation of Dihedral Angles from CH–CH Dipolar–Dipolar Cross-Correlated Relaxation Rates: A C–C Torsion Involving a Quaternary Carbon Atom in Epothilone A Bound to Tubulin

Angewandte Chemie International Edition ◽

10.1002/anie.200350950 ◽

2003 ◽

Vol 42 (22) ◽

pp. 2515-2517 ◽

Author(s):

Teresa Carlomagno ◽

Víctor M. Sánchez ◽

Marcel J. J. Blommers ◽

Christian Griesinger

Keyword(s):

Carbon Atom ◽

Dihedral Angles ◽

Relaxation Rates ◽

Quaternary Carbon ◽

Quaternary Carbon Atom ◽

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One out of Four: Kinetic Resolution of Stereoisomeric Mixtures of Secondary Alcohols with a Quaternary Carbon Atom in the β-Position by Cu–H-Catalyzed Enantioselective Silylation

ACS Organic & Inorganic Au ◽

10.1021/acsorginorgau.1c00050 ◽

2021 ◽

Author(s):

Zaneta Papadopulu ◽

Novid Kazeroonian ◽

Elisabeth Irran ◽

Martin Oestreich

Keyword(s):

Carbon Atom ◽

Kinetic Resolution ◽

Secondary Alcohols ◽

Quaternary Carbon ◽

Quaternary Carbon Atom

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Stereocontrolled synthesis of carbocyclic compounds with a quaternary carbon atom based on SN2′ alkylation of γ,δ-epoxy-α,β-unsaturated ketones

Organic & Biomolecular Chemistry ◽

10.1039/c2ob25719j ◽

2012 ◽

Vol 10 (28) ◽

pp. 5431 ◽

Author(s):

Fumihiko Yoshimura ◽

Ayano Kowata ◽

Keiji Tanino

Keyword(s):

Carbon Atom ◽

Quaternary Carbon ◽

Quaternary Carbon Atom ◽

Unsaturated Ketones ◽

Carbocyclic Compounds ◽

Stereocontrolled Synthesis

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