Three-component coupling of aryl iodides, allenes, and aldehydes catalyzed by a Co/Cr-hybrid catalyst
2018 ◽
Vol 14
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pp. 1413-1420
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Keyword(s):
The cobalt/chromium-catalyzed three-component coupling of aryl iodides, allenes, and aldehydes has been developed to afford multi-substituted homoallylic alcohols in a diastereoselective manner. Control experiments for understanding the reaction mechanism reveal that the cobalt catalyst is involved in the oxidative addition and carbometalation steps in the reaction, whereas the chromium salt generates highly nucleophilic allylchromium intermediates from allylcobalt species, without the loss of stereochemical information, to allow the addition to aldehydes.
2002 ◽
Vol 41
(5)
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pp. 807
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2009 ◽
Vol 49
(3)
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pp. 377-384
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Keyword(s):
2020 ◽
Vol 142
(15)
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pp. 7128-7133
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2014 ◽
Vol 136
(34)
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pp. 11902-11905
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2014 ◽
Vol 136
(42)
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pp. 14654-14657
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1976 ◽
Vol 19
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pp. 165-171
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