Cortical Auditory-Evoked Potentials in Response to Multitone Stimuli in Hearing-Impaired Adults

2016 ◽  
Vol 27 (05) ◽  
pp. 406-415 ◽  
Author(s):  
Fabrice Bardy ◽  
Jessica Sjahalam-King ◽  
Bram Van Dun ◽  
Harvey Dillon
Keyword(s):  
Hearing Loss ◽  
Evoked Potentials ◽  
Hearing Impairment ◽  
Auditory Evoked Potentials ◽  
Hearing Impaired ◽  
Detection Sensitivity ◽  
Auditory Stimuli ◽  
Significant Difference ◽  
Objective Detection ◽  
Cortical Auditory Evoked Potentials

Purpose: To determine if one-octave multitone (MT) stimuli increase the amplitude of cortical auditory-evoked potentials (CAEPs) in individuals with a hearing loss when compared to standard pure-tone (PT) stimuli and narrow-band noise (NBN). Research Design: CAEPs were obtained from 16 hearing-impaired adults in response to PT and MT auditory stimuli centered around 0.5, 1, 2, and 4 kHz and NBN centered around 1 and 2 kHz. Hearing impairment ranged from a mild to a moderate hearing loss in both ears. Auditory stimuli were monaurally delivered through insert earphones at 10 and 20 dB above threshold. The root mean square amplitude of the CAEP and the detectability of the responses using Hotelling’s T2 were calculated and analyzed. Results: CAEP amplitudes elicited with MT stimuli were on average 29% larger than PT stimuli for frequencies centered around 1, 2, and 4 kHz. No significant difference was found for responses to 0.5-kHz stimuli. Significantly higher objective detection scores were found for MT when compared to PT. For the 1- and 2-kHz stimuli, the CAEP amplitudes to NBN were not significantly different to those evoked by PT but a significant difference was found between MT stimuli and both NBN and PT. The mean detection sensitivity of MT for the four frequencies was 80% at 10 dB SL and 95% at 20 dB SL, and was comparable with detection sensitivities observed in normal-hearing participants. Conclusions: Using MT stimuli when testing CAEPs in adults with hearing impairment showed larger amplitudes and a higher objective detection sensitivity compared to using traditional PT stimuli for frequencies centered around 1, 2, and 4 kHz. These findings suggest that MT stimuli are a clinically useful tool to increase the efficiency of frequency-specific CAEP testing in adults with hearing impairment.

scholarly journals Analysis of the Effect of Musical Stimulation on Cortical Auditory Evoked Potentials

2018 ◽  
Vol 23 (01) ◽  
pp. 031-035
Author(s):  
Daiane Lima ◽  
Simone Regaçone ◽  
Anna Oliveira ◽  
Yara Alcântara ◽  
Eduardo Chagas ◽  
...  
Keyword(s):  
Evoked Potentials ◽  
Auditory System ◽  
Repeated Measures ◽  
Auditory Evoked Potentials ◽  
P Value ◽  
Mixed Analysis ◽  
Sphericity Test ◽  
Significant Difference ◽  
Healthy Female ◽  
Cortical Auditory Evoked Potentials

Introduction Cortical auditory evoked potentials (CAEPs) are bioelectric responses that occur from acoustic stimulations, and they assess the functionality of the central auditory system. Objective The objective of the present study was to analyze the effect of musical stimulation on CAEPs. Methods The sample consisted of 42 healthy female subjects, aged between 18 and 24 years, divided into two groups – G1: without musical stimulation prior to the CAEP examination; and G2: with stimulation prior to the examination. In both groups, as a pre-collection procedure, the complete basic audiological evaluation was performed. For the musical stimulation performed in G2, we used an MP4 player programmed to play Pachelbel's “Canon in D Major” for five minutes prior to the CAEP examination. To analyze the effect on the groups, the ear side and the ide–group interaction , a mixed analysis of variance (ANOVA) of repeated measures was performed. Box M test and Mauchly sphericity test were also performed. Results Test differences were considered statistically significant when the p-value was < 0.05 (5%). Thus, it was possible to observe that there was a statistically significant difference of the P2 component characterized by the decrease in the amplitude of response in the left ear in G2 when comparing the responses of CAEP with and without prior musical stimulation. Conclusion The result of the present study enabled us to conclude that there was a change in the response of CAEPs with musical stimulation.

scholarly journals Clinical Experience of Using Cortical Auditory Evoked Potentials in the Treatment of Infant Hearing Loss in Australia

2016 ◽  
Vol 37 (01) ◽  
pp. 036-052 ◽  
Author(s):  
Bram Van Dun ◽  
Alison King ◽  
Lyndal Carter ◽  
Wendy Pearce ◽  
Simone Punch
Keyword(s):  
Hearing Loss ◽  
Evoked Potentials ◽  
Clinical Experience ◽  
Auditory Evoked Potentials ◽  
Cortical Auditory Evoked Potentials

Threshold Estimation Using “Chained Stimuli” for Cortical Auditory Evoked Potentials in Individuals With Normal Hearing and Hearing Impairment

2019 ◽  
Vol 28 (2S) ◽  
pp. 428-436
Author(s):  
Mohan Kumar Kalaiah ◽  
Sanjana Poovaiah ◽  
Usha Shastri
Keyword(s):  
Hearing Loss ◽  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Normal Hearing ◽  
Testing Time ◽  
Threshold Estimation ◽  
Behavioral Threshold ◽  
Hearing Sensitivity ◽  
The Difference ◽  
Cortical Auditory Evoked Potentials

Purpose We investigated the utility of chained stimuli for threshold estimation using cortical auditory evoked potentials (CAEPs) in individuals with normal hearing sensitivity and hearing loss. The effect of the order of frequency in chained stimuli on CAEPs was also studied. Method Seventeen individuals with normal hearing and 17 individuals with mild to severe sensorineural hearing loss participated in the study. In individuals with normal hearing, CAEPs were recorded at 80 dB nHL for 4 chained stimuli with different orders of frequencies within them (Chained Stimuli 1 [CS1]: 500, 1000, 2000, 4000 Hz; Chained Stimuli 2: 4000, 2000, 1000, 500 Hz; Chained Stimuli 3: 500, 2000, 1000, 4000 Hz; Chained Stimuli 4: 4000, 1000, 2000, 500 Hz). CAEP threshold estimation was carried out using CS1 in both groups and was compared with behavioral pure-tone thresholds. Results CS1 elicited the largest amplitude responses at low and mid frequencies, whereas all 4 stimuli elicited similar amplitude responses at high frequencies. CAEP thresholds were generally within 10–20 dB above the participants' behavioral threshold in both groups. The difference between CAEP threshold and behavioral threshold was less for individuals with hearing loss compared to individuals with normal hearing. There was a significant positive correlation between CAEP threshold and behavioral threshold at all the frequencies. Conclusions CS1 could be used to elicit CAEPs for threshold estimation in adult participants with normal hearing and hearing loss of varied degrees with theoretically reduced testing time. The actual time reduction using chained stimuli and the correction factor to be applied to estimate behavioral threshold can be studied in future investigations.

scholarly journals Cortical Auditory Evoked Potentials in Children with a Hearing Loss: A Pilot Study

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Amineh Koravand ◽  
Benoît Jutras ◽  
Maryse Lassonde
Keyword(s):  
Hearing Loss ◽  
Evoked Potentials ◽  
Hearing Aids ◽  
Auditory Processing ◽  
Auditory Evoked Potentials ◽  
Group Differences ◽  
Central Auditory Processing ◽  
Significant Group ◽  
Children With Hearing Loss ◽  
Cortical Auditory Evoked Potentials

Objective. This study examined the patterns of neural activity in the central auditory system in children with hearing loss.Methods. Cortical potentials and mismatch responses (MMRs) were recorded from ten children aged between 9 and 10 years: five with hearing loss and five with normal hearing in passive oddball paradigms using verbal and nonverbal stimuli.Results. Results indicate a trend toward larger P1 amplitude, a significant reduction in amplitude, and latency of N2 in children with hearing loss compared to control. No significant group differences were observed for the majority of the MMRs conditions.Conclusions. Data suggest that the reduced auditory input affects the pattern of cortical-auditory-evoked potentials in children with a mild to moderately severe hearing loss. Results suggest maturational delays and/or deficits in central auditory processing in children with hearing loss, as indicated by the neurophysiological markers P1 and N2. In contrast, negative MMR data suggest that the amplification provided by the hearing aids could have allowed children with hearing loss to develop adequate discriminative abilities.

Cortical Auditory-Evoked Potentials (CAEPs) in Adults in Response to Filtered Speech Stimuli

2013 ◽  
Vol 24 (09) ◽  
pp. 807-822 ◽  
Author(s):  
Lyndal Carter ◽  
Harvey Dillon ◽  
John Seymour ◽  
Mark Seeto ◽  
Bram Van Dun
Keyword(s):  
Hearing Loss ◽  
Evoked Potentials ◽  
Hearing Aids ◽  
Auditory Evoked Potentials ◽  
Hearing Aid ◽  
Speech Sounds ◽  
Sensation Level ◽  
Behavioral Threshold ◽  
Speech Stimuli ◽  
Cortical Auditory Evoked Potentials

Background: Previous studies have demonstrated that cortical auditory-evoked potentials (CAEPs) can be reliably elicited in response to speech stimuli in listeners wearing hearing aids. It is unclear, however, how close to the aided behavioral threshold (i.e., at what behavioral sensation level) a sound must be before a cortical response can reliably be detected. Purpose: The purpose of this study was to systematically examine the relationship between CAEP detection and the audibility of speech sounds (as measured behaviorally), when the listener is wearing a hearing aid fitted to prescriptive targets. A secondary aim was to investigate whether CAEP detection is affected by varying the frequency emphasis of stimuli, so as to simulate variations to the prescribed gain-frequency response of a hearing aid. The results have direct implications for the evaluation of hearing aid fittings in nonresponsive adult clients, and indirect implications for the evaluation of hearing aid fittings in infants. Research Design: Participants wore hearing aids while listening to speech sounds presented in a sound field. Aided thresholds were measured, and cortical responses evoked, under a range of stimulus conditions. The presence or absence of CAEPs was determined by an automated statistic. Study Sample: Participants were adults (6 females and 4 males). Participants had sensorineural hearing loss ranging from mild to severe-profound in degree. Data Collection and Analysis: Participants' own hearing aids were replaced with a test hearing aid, with linear processing, during assessments. Pure-tone thresholds and hearing aid gain measurements were obtained, and a theoretical prediction of speech stimulus audibility for each participant (similar to those used for audibility predictions in infant hearing aid fittings) was calculated. Three speech stimuli, (/m/, /t/, and /g/) were presented aided (monaurally, nontest ear occluded), free field, under three conditions (+4 dB/octave, −4 dB/octave, and without filtering), at levels of 40, 50, and 60 dB SPL (measured for the unfiltered condition). Behavioral thresholds were obtained, and CAEP recordings were made using these stimuli. The interaction of hearing loss, presentation levels, and filtering conditions resulted in a range of CAEP test behavioral sensation levels (SLs), from −25 to +40 dB. Results: Statistically significant CAEPs (p < .05) were obtained for virtually every presentation where the behavioral sensation level was >10 dB, and for only 5% of occasions when the sensation level was negative. In these (“false-positive”) cases, the greatest (negative) sensation level at which a CAEP was judged to be present was −6 dB SL. Conclusions: CAEPs are a sensitive tool for directly evaluating the audibility of speech sounds, at least for adult listeners. CAEP evaluation was found to be more accurate than audibility predictions, based on threshold and hearing aid response measures.

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