scholarly journals Investigations on the Performance of Polymer Gel Dosimeter for Radiation Therapy

RADIOISOTOPES ◽  
2008 ◽  
Vol 57 (3) ◽  
pp. 183-188
Author(s):  
Kiyofumi HANEDA ◽  
Hiroki OKUDO ◽  
Yusuke TSUNEI ◽  
Munenori YOSHIOKA ◽  
Shin-ichiro HAYASHI ◽  
...  
Author(s):  
S F Ghoreishi ◽  
J Beik ◽  
I Shiri ◽  
K Kh Keshavarzi ◽  
S R M Mahdavi

Background:Currently, the potential application of gold nanoparticles (AuNPs) to increase the efficiency of radiation therapy has been widely investigated. However, lack of an appropriate method to estimate the dose distribution in a nanoparticle-laden tissue limits the applicability of nanoparticles in radiotherapy clinics. Polymer gel dosimetry provides an accurate and precise system that facilitates the measurement of dose distribution in full three dimensions.Objective: In this study, the effect of radiation dose enhancement of AuNPs was assessed through gel dosimetry analysis.Material and Methods: For this purpose, AuNPs were integrated in MAGIC_f polymer gel dosimeter and irradiated by 6 Mv X-ray beam. The irradiated gel was then evaluated through two modalities of magnetic resonance imaging (MRI) and optical computed tomography (OCT).Result: MRI and OCT scanning of MAGIC_f gels containing 0.1 mM AuNPs demonstrated dose enhancements of 7.8% and 6.8%, respectively.Conclusion: Polymer gel dosimetry has the potential to provide a new platform for the investigation and optimization of the applicability of nanoparticles in radiation therapy.


2022 ◽  
Vol 190 ◽  
pp. 109804
Author(s):  
Akbar Aliasgharzadeh ◽  
Vahid Anaraki ◽  
Daryoush Khoramian ◽  
Mahdi Ghorbani ◽  
Bagher Farhood

1994 ◽  
Vol 39 (9) ◽  
pp. 1437-1455 ◽  
Author(s):  
M J Maryanski ◽  
R J Schulz ◽  
G S Ibbott ◽  
J C Gatenby ◽  
J Xie ◽  
...  

2015 ◽  
Vol 105 ◽  
pp. 98-104 ◽  
Author(s):  
Facundo Mattea ◽  
David Chacón ◽  
José Vedelago ◽  
Mauro Valente ◽  
Miriam C. Strumia

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