Obstructive sleep apnea syndrome: is it different in women?
Traditionally, obstructive sleep apnea syndrome (OSAS) was regarded by the medical community as a men’s disease. Current data shows indeed that the prevalence of OSAS is higher among men than women. However, in postmenopausal women the prevalence of OSAS is high. Differences between men and women in the prevalence of OSAS drop as age increases, mainly as a result of a marked increase in the prevalence and severity of respiratory sleep disorders in women after menopause. There are some differences regarding the clinical manifestations of OSAS in women and men. Also, it seems that women with moderate OSAS are more susceptible to cardiovascular consequences of OSAS compared with men, having a higher degree of endothelial dysfunction. Gender differences in the response to different therapeutic strategies for OSAS are still not known with certainty.