scholarly journals Modeling the High-resolution Emission Spectra of Clear and Cloudy Nontransiting Hot Jupiters

2021 ◽  
Vol 923 (1) ◽  
pp. 62
Author(s):  
Isaac Malsky ◽  
Emily Rauscher ◽  
Eliza M.-R. Kempton ◽  
Michael Roman ◽  
Deryl Long ◽  
...  

Abstract The advent of high-resolution spectroscopy (R ≳ 25,000) as a method for characterization of exoplanet atmospheres has expanded our capability to study nontransiting planets, vastly increasing the number of planets accessible for observation. Many of the most favorable targets for atmospheric characterization are hot Jupiters, where we expect large spatial variation in physical conditions such as temperature, wind speed, and cloud coverage, making viewing geometry important. Three-dimensional models have generally simulated observational properties of hot Jupiters assuming edge-on viewing, which can be compared to observations of transiting planets, but neglected the large fraction of planets without nearly edge-on orbits. As the first investigation of how orbital inclination manifests in high-resolution emission spectra from three-dimensional models, we use a general circulation model to simulate the atmospheric structure of Upsilon Andromedae b, a typical nontransiting hot Jupiter with high observational interest, due the brightness of its host star. We compare models with and without clouds, and find that cloud coverage intensifies spatial variations by making colder regions dimmer and relatedly enhancing emission from the clear, hotter regions. This increases both the net Doppler shifts and the variation of the continuum flux amplitude over the course of the planet’s orbit. In order to accurately capture scattering from clouds, we implement a generalized two-stream radiative transfer routine for inhomogeneous multiple scattering atmospheres. As orbital inclination decreases, four key features of the high-resolution emission spectra also decrease in both the clear and cloudy models: (1) the average continuum flux level, (2) the amplitude of the variation in continuum with orbital phase, (3) net Doppler shifts of spectral lines, and (4) Doppler broadening in the spectra. Models capable of treating inhomogeneous cloud coverage and different viewing geometries are critical in understanding results from high-resolution emission spectra, enabling an additional avenue to investigate these extreme atmospheres.

Author(s):  
Cristina Càndito

In the present contribution, the author presents research on the Winter Room of Palazzo Brignole-Sale (Palazzo Rosso) in Genoa, Italy, which is part of the decorative cycle of the Seasons. The cycle displays the peculiar characteristics of the seventeenth-century Genoese decorative style, where architecture, painting, furniture and stuccos are highly interconnected. The research was carried out using the data collected with nodal-photography techniques. Thanks to these techniques, it was to possible to obtain an interactive panoramic spherical photo and high-resolution scaled photos of planar projections of the architectural perspective, in order to identify the real and illusory space. The analysis proceeded with a series of reverse-perspective constructions and the consequent reconstruction (using three-dimensional models) of the possible virtual space represented in the paintings. Thanks to this information, the author was able to carry out the necessary study to understand the peculiar characteristics of the decorations, the optical illusions of which are extremely impressive.


2021 ◽  
Vol 908 (1) ◽  
pp. 101
Author(s):  
Michael T. Roman ◽  
Eliza M.-R. Kempton ◽  
Emily Rauscher ◽  
Caleb K. Harada ◽  
Jacob L. Bean ◽  
...  

1975 ◽  
Vol 39 (8) ◽  
pp. 544-546
Author(s):  
HL Wakkerman ◽  
GS The ◽  
AJ Spanauf

2020 ◽  
Vol 17 (4) ◽  
pp. 342-351
Author(s):  
Sergio A. Durán-Pérez ◽  
José G. Rendón-Maldonado ◽  
Lucio de Jesús Hernandez-Diaz ◽  
Annete I. Apodaca-Medina ◽  
Maribel Jiménez-Edeza ◽  
...  

Background: The protozoan Giardia duodenalis, which causes giardiasis, is an intestinal parasite that commonly affects humans, mainly pre-school children. Although there are asymptomatic cases, the main clinical features are chronic and acute diarrhea, nausea, abdominal pain, and malabsorption syndrome. Little is currently known about the virulence of the parasite, but some cases of chronic gastrointestinal alterations post-infection have been reported even when the infection was asymptomatic, suggesting that the cathepsin L proteases of the parasite may be involved in the damage at the level of the gastrointestinal mucosa. Objective: The aim of this study was the in silico identification and characterization of extracellular cathepsin L proteases in the proteome of G. duodenalis. Methods: The NP_001903 sequence of cathepsin L protease from Homo sapienswas searched against the Giardia duodenalisproteome. The subcellular localization of Giardia duodenaliscathepsin L proteases was performed in the DeepLoc-1.0 server. The construction of a phylogenetic tree of the extracellular proteins was carried out using the Molecular Evolutionary Genetics Analysis software (MEGA X). The Robetta server was used for the construction of the three-dimensional models. The search for possible inhibitors of the extracellular cathepsin L proteases of Giardia duodenaliswas performed by entering the three-dimensional structures in the FINDSITEcomb drug discovery tool. Results: Based on the amino acid sequence of cathepsin L from Homo sapiens, 8 protein sequences were identified that have in their modular structure the Pept_C1A domain characteristic of cathepsins and two of these proteins (XP_001704423 and XP_001704424) are located extracellularly. Threedimensional models were designed for both extracellular proteins and several inhibitory ligands with a score greater than 0.9 were identified. In vitrostudies are required to corroborate if these two extracellular proteins play a role in the virulence of Giardia duodenalisand to discover ligands that may be useful as therapeutic targets that interfere in the mechanism of pathogenesis generated by the parasite. Conclusion: In silicoanalysis identified two proteins in the Giardia duodenalisprotein repertoire whose characteristics allowed them to be classified as cathepsin L proteases, which may be secreted into the extracellular medium to act as virulence factors. Three-dimensional models of both proteins allowed the identification of inhibitory ligands with a high score. The results suggest that administration of those compounds might be used to block the endopeptidase activity of the extracellular cathepsin L proteases, interfering with the mechanisms of pathogenesis of the protozoan parasite Giardia duodenalis.


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