scholarly journals Prevalence of Trypanosoma Cruzi antibodies in blood donors from the Sao Paulo State, Brazil, between 2012 and 2014

2017 ◽  
Vol 11 (03) ◽  
pp. 277-281 ◽  
Author(s):  
Svetoslav Nanev Slavov ◽  
Katia Kaori Otaguiri ◽  
Mariana Tomazini Pinto ◽  
Vanderléia Bárbaro Valente ◽  
Eugênia Maria Amorim Ubiali ◽  
...  

Introduction: American tripanosomiasis (Chagas disease), the second most neglected disease in the world, is caused by the protozoan parasite Trypanosoma cruzi. Though natural transmission by insect vectors has been controlled, there is significant risk of T. cruzi transmission by blood transfusion in non-endemic regions, generally due to immigration processes from endemic areas. Methodology: The objective of this study was to evaluate anti-T. cruzi seroprevalence in blood donors from the western part of São Paulo State, Brazil, by serologic and immunofluorescence confirmation tests for the period between 2012 and 2014. Currently, this region is regarded as a non-endemic area for Chagas disease. Results: The confirmed overall T. cruzi seroprevalence among blood donors was 0.10%, which can be considered low compared to other Brazilian regions. Nevertheless, the distribution of the anti-T. cruzi antibodies within the examined region was uneven, and some areas of significantly higher prevalence were observed. Conclusions: We could consider two tendencies in the prevalence of T. cruzi: (i) residual older undiagnosed cases from São Paulo State, and (ii) immigration from endemic Brazilian or South American regions. The discordance obtained for T. cruzi prevalence by serologic and immunofluorescence methods demonstrates that more specific routine diagnosis is needed to diminish the cost of the assays and the loss of blood supply once all seropositive blood bags are immediately discarded.

2020 ◽  
Vol 80 (1) ◽  
pp. 111-115 ◽  
Author(s):  
Svetoslav Nanev Slavov ◽  
Rafael Rahal Guaragna Machado ◽  
Alexander Rodrigo Ferreira ◽  
Camila Pereira Soares ◽  
Danielle Bastos Araujo ◽  
...  

Transfusion ◽  
2017 ◽  
Vol 57 (12) ◽  
pp. 2897-2901 ◽  
Author(s):  
Svetoslav N. Slavov ◽  
Marta R. Hespanhol ◽  
Evandra S. Rodrigues ◽  
José E. Levi ◽  
Eugênia M.A. Ubiali ◽  
...  

1988 ◽  
Vol 30 (6) ◽  
pp. 437-440
Author(s):  
Dalva Marli Valério Wanderley ◽  
Luís Marcelo Aranha Camargo ◽  
Maria Esther de Carvalho

Report of a case of acute transfusional Chagas'disease in a four-year-old child with a previous diagnosis of acute lymphocytic leukemia, transmitted in São Paulo, the Capital of São Paulo State, Brazil. Epidemiological investigation disclosed the donor's serological positivity and his previous residence in an area where Chagas' disease is endemic. The importance of adequate sorological screening in blood donors is evident. It should be stressed that this is the first case notified to the Superintendência de Controle de Endemias (SUCEN) (Superintendency for the Endemy Control) of the State Secretariat of Health, São Paulo, for the last five years.


Author(s):  
Svetoslav N. Slavov ◽  
Elaine V. Santos ◽  
Marta R. Hespanhol ◽  
Evandra S. Rodrigues ◽  
Rodrigo Haddad ◽  
...  

2019 ◽  
Vol 29 (5) ◽  
pp. 358-363
Author(s):  
S. N. Slavov ◽  
I. S. Christova ◽  
A. R. Ferreira ◽  
E. S. Rodrigues ◽  
M. L. Bianquini ◽  
...  

Author(s):  
Rafael dos Santos Bezerra ◽  
Kamila Chagas Peronni ◽  
Bruna Durães de Figueiredo Barros ◽  
Leonardo Scalon de Oliveira ◽  
Evandra Strazza Rodrigues ◽  
...  

2019 ◽  
Vol 101 (1) ◽  
pp. 113-115 ◽  
Author(s):  
Kelly Cristine Borsatto ◽  
Yago Visinho dos Reis ◽  
Ariane Cristina Caris Garcia ◽  
Paulo Sergio de Sousa ◽  
Maria Tercília Vilela de Azeredo-Oliveira ◽  
...  

1997 ◽  
Vol 39 (3) ◽  
pp. 171-174 ◽  
Author(s):  
Ricardo Mário de Carvalho CIARAVOLO ◽  
Maria de Fátima DOMINGOS ◽  
Dalva Marli Valério WANDERLEy ◽  
Laércio José GERBI ◽  
Pedro Paulo CHIEFFI ◽  
...  

Since the beginning of the seventies the natural transmission of Chagas’ infection has been considered to be under control in the State of São Paulo and not even a case of American Trypanosomiasis, transmitted by triatomine bugs, has been detected by the epidemiological surveillance system. This situation justifies the report of a case of acute Chagas’ disease that occurred in a forest area considered free of domiciliary triatomines along the Southern seacoast of São Paulo State. In May, 1995 the presence of trypomastigote forms of Trypanosoma cruzi had been diagnosed in a retired 57 year-old male patient, born and living in Santos (São Paulo State), complaining of fever, fatigue and malaise. The patient reported that 40 days before he had participated with 17 friends in a 7-day excursion in a forest area of the municipalities of Itanhaém and Peruíbe. During this period the group had been lodged in three houses located within the forest. Eight days after the end of the excursion the patient began to have fever, malaise and fatigue. During the next 31 days he had received medical care both as an inpatient and an outpatient, without any significant improvement. After the detection of T. cruzi trypomastigotes in his blood stream the patient began to be treated with benzonidazole in a hospital but died 8 days after the beginning of treatment. The epidemiological investigation carried out showed no signs of the presence of triatomine bugs in the three houses where the group had been lodged, or any indication of Chagas' infection in other excursionists


Sign in / Sign up

Export Citation Format

Share Document