scholarly journals Effective treatment of apatinib for chemotherapy‑refractory advanced gastric carcinoma with AFP‑secretion and HER2‑positivity: A case report

2021 ◽  
Vol 15 (2) ◽  
Author(s):  
Xinjing Ding ◽  
Jianghua Ding
Keyword(s):  
Case Report ◽  
Gastric Carcinoma ◽  
Effective Treatment ◽  
Advanced Gastric Carcinoma ◽  
Her2 Positivity

scholarly journals Synchronous Occurrence of Advanced Gastric Carcinoma with Retroperitoneal Liposarcoma: A Case Report

2021 ◽  
Vol 23 ◽  
Author(s):  
Hiroshi Kobayashi ◽  
Riuko Ohashi ◽  
Masuo Ujita ◽  
Kana Ueki ◽  
Ryouya Seki ◽  
...  
Keyword(s):  
Case Report ◽  
Gastric Carcinoma ◽  
Retroperitoneal Liposarcoma ◽  
Advanced Gastric Carcinoma

scholarly journals Locally Advanced Gastric Carcinoma: A Case Report

2020 ◽  
Vol 45 (6) ◽  
pp. 764-768
Author(s):  
Ryo Oono ◽  
Hideaki Murase ◽  
Satoshi Yosinouchi ◽  
Kyoko Higuchi ◽  
Yuta Suzuki ◽  
...  
Keyword(s):  
Case Report ◽  
Gastric Carcinoma ◽  
Locally Advanced ◽  
Advanced Gastric Carcinoma

scholarly journals First-line treatment of apatinib in elderly patient of advanced gastric carcinoma: A case report of NGS-driven targeted therapy

2018 ◽  
Vol 19 (5) ◽  
pp. 355-358
Author(s):  
Yan Yang ◽  
Wuqiong Zhang ◽  
Jinghao Yao ◽  
Jing Liu ◽  
Shukui Qin ◽  
...  
Keyword(s):  
Elderly Patient ◽  
Case Report ◽  
Targeted Therapy ◽  
Gastric Carcinoma ◽  
Line Treatment ◽  
First Line ◽  
Advanced Gastric Carcinoma ◽  
First Line Treatment

scholarly journals Complete remission after chemotherapy for advanced gastric carcinoma^|^mdash;a case report^|^mdash;

2012 ◽  
Vol 73 (3) ◽  
pp. 581-587
Author(s):  
Masaharu HIGASHIDA ◽  
Hideo MATSUMOTO ◽  
Hirotake NISHIMURA ◽  
Masafumi NAKAMURA ◽  
Toshihiro HIRAI
Keyword(s):  
Case Report ◽  
Complete Remission ◽  
Gastric Carcinoma ◽  
Advanced Gastric Carcinoma

Advanced gastric carcinoma in an 18-year-old man: A case report

1998 ◽  
Vol 3 (3) ◽  
pp. 182-185
Author(s):  
Hiroyuki Konno ◽  
Megumi Baba ◽  
Kinji Kamiya ◽  
Yuji Maruo ◽  
Tatsuo Tanaka ◽  
...  
Keyword(s):  
Case Report ◽  
Gastric Carcinoma ◽  
Advanced Gastric Carcinoma

HER2 Expression in Gastric Cancer and Gastroesophageal Junction Cancer

2020 ◽  
Vol 22 (2) ◽  
pp. 79-82
Author(s):  
Md Azizur Rahman ◽  
Abdullah Md Abu Ayub Ansari ◽  
Kazi Mazharul Islam ◽  
Md Aminur Rahman ◽  
ABM Abdul Matin ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Gastric Carcinoma ◽  
Social Impact ◽  
Gastroesophageal Junction ◽  
Treatment Protocol ◽  
Armed Forces ◽  
Her2 Expression ◽  
Her2 Positive ◽  
Cancer Data ◽  
Her2 Positivity

Background: Carcinoma of the stomach is a major cause of cancer mortality worldwide. Due to social impact of gastric carcinoma (GC), there is a need to stratify patients into appropriate screening, surveillance and treatment programs. Although histopathology remains the most reliable and less expensive method, numerous efforts have been made to identify and validate novel biomarkers to accomplish the goals. In recent years, several molecules have been identified and tested for their clinical relevace in GC management. Among the biomarkers with the exception of HER2, none of the biomarkers is currently used in clinical practice, and some of them were described in single studies. Materials and Methods: This prospective type of observational study was performed in the Department of Surgery, Dhaka Medical College Hospital, Dhaka, 6 months from approval of protocol. Total 45 consecutive patients aged 18 years and above without consideration of gender were selected purposefully. Every patient was evaluated by clinical examination, appropriate investigations and after a confirm diagnosis of the tissue from the cancer. All patients have undergone operative intervention and Gastrectomy specimens were subtotal (including cardiac and pylorus), subtotal (including the pylorus), total radical gastrectomy and oesophago-gastrectomy sample. All specimens obtained were immersed in 10% formalin. Samples of whom were sent to the department of pathology, DMCH for histopathology examination. Portion of representative tissue/block was sent to AFIP (Armed Forces Institute of Pathology, Dhaka) for immunohistochemistry to find out the HER2 expression in gastric cancer and gastro-oesophageal cancer. Data was collected in a pre-designed questionnaire by face to face interview. Result and observation: In this study when 45 cases were categorized according to WHO grading system it was observed that majority (30) patients were found in grade II, among them 3(10%) were HER2 positive. But with grade III tumour the HER2 positivity were found more i,e; 37.5% (3/8). Grade- I tumor show HER2 neu expression 28.57% (2/7) and according to location most of the cases with HER2 positive expression was located in the gastro-esophageal junction which is 27.27% (3/11) than gastric carcinoma which is 14.70% (5/34). Conclusion: Most of the patients of gastric and gastrooesophageal junction adenocarcinoma are diagnosed at a very late stage, so they require special attention in treatment protocol, including chemotherapy and immunotherapy for increasing their survivability. The study showed with poorly differentiated (high grade) tumour, the HER2 positivity were found more. Journal of Surgical Sciences (2018) Vol. 22 (2) : 79-82

Treatment of middle aortic syndrome with thoraco-abdominal aortic bypass grafting assisted by endoscope in adult

Perfusion ◽  
2021 ◽  
pp. 026765912098677
Author(s):  
Chuntian Li ◽  
Xin Mao ◽  
Xu Zhao ◽  
Guiqing Liu ◽  
Gang Xu ◽  
...  
Keyword(s):  
Case Report ◽  
Effective Treatment ◽  
Rare Disease ◽  
Abdominal Aorta ◽  
Surgical Approach ◽  
Endoscopic Technique ◽  
Bypass Grafting ◽  
Middle Aortic Syndrome ◽  
Aortic Bypass ◽  
Abdominal Aortic

Middle aortic syndrome (MAS) is a rare disease characterized by distal thoracic aorta or abdominal aorta coarctation, and thoraco-abdominal aortic bypass grafting is an effective treatment for this condition. However, significant trauma is associated with the conventional surgical approach. We report a 26-year-old woman with MAS who presented with hypertension and needed thoraco-abdominal bypass grafting. In this operation, we adopted the endoscopic technique to improve the conventional surgical approach (reduce the incision). This case report shows that it is safe and feasible to use an endoscopic technique to reduce the trauma during this kind of operation, and provides a reference for similar treatments.

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