Novel AXL‑targeted agents overcome FLT3 inhibitor resistance in FLT3‑ITD+ acute myeloid leukemia cells

Oncology Letters ◽

10.3892/ol.2021.12658 ◽

2021 ◽

Vol 21 (5) ◽

Author(s):

Yi Liu ◽

Jing Wei ◽

Jiaxin Liu ◽

Weina Ma ◽

Yanting Duan ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Targeted Agents ◽

Flt3 Inhibitor ◽

Acute Myeloid Leukemia Cells ◽

Inhibitor Resistance ◽

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The Dual MEK/FLT3 Inhibitor E6201 Exerts Cytotoxic Activity against Acute Myeloid Leukemia Cells Harboring Resistance-Conferring FLT3 Mutations

Cancer Research ◽

10.1158/0008-5472.can-15-1580 ◽

2016 ◽

Vol 76 (6) ◽

pp. 1528-1537 ◽

Author(s):

Weiguo Zhang ◽

Gautam Borthakur ◽

Chen Gao ◽

Ye Chen ◽

Hong Mu ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Cytotoxic Activity ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Flt3 Inhibitor ◽

Flt3 Mutations ◽

Acute Myeloid Leukemia Cells ◽

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Quizartinib, a selective FLT3 inhibitor, maintains antileukemic activity in preclinical models of RAS-mediated midostaurin-resistant acute myeloid leukemia cells

10.18632/oncotarget.27489 ◽

2020 ◽

Vol 11 (11) ◽

pp. 943-955 ◽

Author(s):

Tomoya Aikawa ◽

Noriko Togashi ◽

Koichi Iwanaga ◽

Hiroyuki Okada ◽

Yumi Nishiya ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Antileukemic Activity ◽

Preclinical Models ◽

Flt3 Inhibitor ◽

Acute Myeloid Leukemia Cells ◽

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miRNa-494 inhibits apoptosis and promotes autophagy of acute myeloid leukemia cells by downregulating FGFR2

Minerva Endocrinologica ◽

10.23736/s0391-1977.19.03062-1 ◽

2020 ◽

Vol 44 (4) ◽

Author(s):

Zongbao Liu ◽

Yuzhong Hua ◽

Cun Liu ◽

Shaoyun Cheng

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Acute Myeloid Leukemia Cells ◽

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Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015)

10.26756/th.2015.50 ◽

2015 ◽

Author(s):

Daniel Fadi Azar

Keyword(s):

Acute Myeloid Leukemia ◽

Organic Compounds ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Acute Myeloid Leukemia Cells ◽

Metal Organic ◽

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The anticancer effect of Î²-2 himachalen-6-ol from Lebanese wild carrot on human acute myeloid leukemia cells. (c2016)

10.26756/th.2016.3 ◽

2016 ◽

Author(s):

Joelle C. Boulos

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Anticancer Effect ◽

Wild Carrot ◽

Human Acute Myeloid Leukemia ◽

Acute Myeloid Leukemia Cells ◽

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Antiproliferative and Apoptotic Effects of Two New Pd(II) Methylsarcosinedithiocarbamate Derivatives on Human Acute Myeloid Leukemia Cells In Vitro

Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics ◽

10.3727/096504008785055558 ◽

2008 ◽

Vol 17 (3) ◽

pp. 103-113 ◽

Author(s):

Donatella Aldinucci ◽

Lara Cattaruzza ◽

Debora Lorenzon ◽

Lorena Giovagnini ◽

Dolores Fregona ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Human Acute Myeloid Leukemia ◽

Acute Myeloid Leukemia Cells ◽

Apoptotic Effects ◽

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Targeting NAT10 Induces Apoptosis by Enhancing Endoplasmic Reticulum Stress in Acute Myeloid Leukemia Cells

SSRN Electronic Journal ◽

10.2139/ssrn.3517398 ◽

2020 ◽

Author(s):

Jie Zi ◽

Qi Han ◽

Siyu Gu ◽

Chunhua Song ◽

Zheng Ge

Keyword(s):

Endoplasmic Reticulum ◽

Acute Myeloid Leukemia ◽

Endoplasmic Reticulum Stress ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Acute Myeloid Leukemia Cells ◽

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Effect of miR-128 in DNA Damage of HL-60 Acute Myeloid Leukemia Cells

Current Pharmaceutical Biotechnology ◽

10.2174/1389201015666140519122524 ◽

2014 ◽

Vol 15 (5) ◽

pp. 492-502 ◽

Author(s):

Hugo Seca ◽

Raquel Lima ◽

Gabriela Almeida ◽

Manuel Sobrinho-Simoes ◽

Rui Bergantim ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Acute Myeloid Leukemia Cells ◽

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Circular RNA circ_0005774 contributes to proliferation and suppresses apoptosis of acute myeloid leukemia cells via circ_0005774/miR-192–5p/ULK1 ceRNA pathway

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2021.02.058 ◽

2021 ◽

Vol 551 ◽

pp. 78-85

Author(s):

Qinghua Li ◽

Qingxia Luan ◽

Hailing Zhu ◽

Yuehua Zhao ◽

Jiafen Ji ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Circular Rna ◽

Leukemia Cells ◽

Acute Myeloid Leukemia Cells ◽

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Targeting NF-κB–dependent alkaliptosis for the treatment of venetoclax-resistant acute myeloid leukemia cells

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2021.05.049 ◽

2021 ◽

Vol 562 ◽

pp. 55-61

Author(s):

Shan Zhu ◽

Jiao Liu ◽

Rui Kang ◽

Minghua Yang ◽

Daolin Tang

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Acute Myeloid Leukemia Cells ◽

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