scholarly journals Tunnelled hemodialysis catheter-related bloodstream infection with Ochrobactrum anthropi: a report of the first two cases from Bulgaria and a brief overview

Folia Medica ◽  
2021 ◽  
Vol 63 (1) ◽  
pp. 148-152
Author(s):  
Biser K. Borisov ◽  
Hristina Y. Hitkova ◽  
Stela P. Linkova
Keyword(s):  
Bloodstream Infection ◽  
Hemodialysis Patients ◽  
High Morbidity ◽  
Ochrobactrum Anthropi ◽  
Central Venous ◽  
Hemodialysis Catheter ◽  
Stage Renal Disease ◽  
End Stage ◽  
Catheter Related Bloodstream Infection

The use of central venous catheters for hemodialysis continues to grow worldwide, despite the efforts of many specialists. Patients with end-stage renal disease have impaired immunity, which is why infections are the most common complication seen in them. It worsens their quality of life and is a major cause of high morbidity and mortality, especially in hemodialysis patients. We report two cases of catheter-related bloodstream infection in hemodialysis patients caused by Ochrobactrum anthropi, which are the first reported cases in Bulgaria and present a brief literature review of the known facts.

scholarly journals Catheter-related blood stream infection in hemodialysis patients with symmetric tunneled non-side-hole hemodialysis catheters

2021 ◽  
pp. 112972982110270
Author(s):  
Michael G Tal ◽  
Alexander S Yevzlin
Keyword(s):  
Bloodstream Infection ◽  
Blood Stream Infection ◽  
Bloodstream Infections ◽  
Blood Stream ◽  
Hemodialysis Patients ◽  
Side Hole ◽  
Hemodialysis Catheter ◽  
Catheter Tip ◽  
Stage Renal Disease ◽  
Catheter Related Bloodstream Infection

Background: Tunneled hemodialysis catheter-related bloodstream infection is a major cause of morbidity and mortality in end-stage renal disease patients. Side holes positioned near the tip of catheters have been linked to formation of thrombi, which, in turn, have been implicated in predisposition to infection. In addition, side holes allow spillage of catheter locking solution, including antibiotics, thereby minimizing the lock solution’s effect on the catheter tip. This study assessed the infection events that occurred in a series of hemodialysis patients using a non-side-hole catheter. Methods: Over a period of 2 years, a novel symmetric-tip non-side-hole catheter was placed in 60 patients. Hemodialysis was performed thrice weekly. Prescribed dialyzer flows were 300–350 mL/min. Catheters were routinely locked with heparin 5000 units/mL between treatments. Patients were followed up for any catheter related complications, specifically infection events. Results: Seven events of catheter-related bloodstream infection occurred for a rate of 0.76 events per 1000 catheter-days, with the first event occurring 9 weeks after insertion. These events were treated by locking the affected catheter with 2 g of clindamycin in 2 mL of heparin 1000 units/mL and administration of intravenous antibiotics, in most cases, for 7–14 days. Two catheters were removed due to infection. Conclusions: Catheter-related bloodstream infections with non-side-hole hemodialysis catheters do occur at a relatively low rate and in this initial preliminary study it seems that most of these infections can be successfully treated without removal of the affected catheters.

A 2% taurolidine catheter lock solution prevents catheter-related bloodstream infection (CRBSI) and catheter dysfunction in hemodialysis patients

2021 ◽  
Vol 30 (14) ◽  
pp. S24-S32
Author(s):  
Matthias Alexander Neusser ◽  
Irina Bobe ◽  
Anne Hammermeister ◽  
Udo Wittmann
Keyword(s):  
Adverse Events ◽  
Bloodstream Infection ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Technical Problems ◽  
Hemodialysis Catheter ◽  
Catheter Dysfunction ◽  
Lock Solution ◽  
Catheter Lock ◽  
Catheter Related Bloodstream Infection

HIGHLIGHTS 2% taurolidine catheter lock solution without additives is safe and efficient. CRBSI and dysfunction rates compare favorably against other studies in hemodialysis Background: In hemodialysis patients, catheter-related bloodstream infection (CRBSI) and catheter dysfunction are common and cause significant morbidity, mortality, and costs. Catheter lock solutions reduce CRBSI and catheter dysfunction rates, but solutions containing heparin, citrate, or antibiotics are associated with adverse effects. Due to its antimicrobial and antithrombotic properties and benign safety profile, taurolidine is suitable for use in catheter lock solutions. In this study the effectiveness and safety of a catheter lock solution containing 2% taurolidine without citrate or heparin (TauroSept®, Geistlich Pharma AG, Wolhusen, Switzerland) in hemodialysis patients were investigated for the first time. Methods: Data from 21 patients receiving chronic hemodialysis via tunneled central venous catheters with 2% taurolidine solution as a catheter lock were analyzed in a single-center retrospective study and compared with the existing literature in a review. The primary endpoint was CRBSI rate. Secondary endpoints included catheter dysfunction, treatment, and costs; catheter technical problems, resolution, and costs; and adverse events. Data were compared to outcomes with standard lock solutions in the literature. Results: No CRBSIs occurred during the observation period of 5,639 catheter days. The catheter dysfunction rate was 0.71 per 1,000 catheter days, and the catheter dysfunction treatment costs were CHF (Swiss Franc) 543 per patient. No technical problems or adverse events related to the use of 2% taurolidine-containing catheter lock solution were observed. These results compare favorably with other catheter lock solutions. Conclusions: A solution containing 2% taurolidine seems suitable as a hemodialysis catheter lock. In a Swiss cohort, it prevented CRBSI, limited catheter dysfunction, and was cost-efficient.

Effect of Intradialytic Parenteral Nutrition on Quality of Life in Hemodialysis Patients

1993 ◽  
Vol 16 (8) ◽  
pp. 599-603 ◽  
Author(s):  
M.S. Siskind ◽  
Y-H. H. Lien
Keyword(s):  
Quality Of Life ◽  
Parenteral Nutrition ◽  
High Efficiency ◽  
Hemodialysis Patients ◽  
Dialysis Session ◽  
Eligibility Requirements ◽  
Stage Renal Disease ◽  
End Stage ◽  
Intradialytic Parenteral Nutrition

The purpose of this study was to determine the effect of intradialytic parenteral nutrition (IDPN) on the quality of life of malnourished patients with end-stage renal disease on high-efficiency and high-flux hemodialysis therapy. Patients, who met the Medicare eligibility requirements for IDPN, were asked to fill out and extensive questionnaire covering several measures of quality of life prior to initiating and again after completing four months of IDPN therapy. Although the IDPN improved serum albumin levels significantly, aside from improved sleep patterns, no significant improvements in quality of life could be demonstrated. The mortality rate of these enrolled patients was as high as 28% within 4 months. We concluded that the limited amount of nutrition delivered over the course of a short dialysis session may not be enough to appreciably change the lives of our malnourished patients.

scholarly journals Physical Activity and Quality of Sleep in Patients with End-Stage Renal Disease on Hemodialysis: A Preliminary Report

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Vasiliki Theodorou ◽  
Eleni Karetsi ◽  
Zoe Daniil ◽  
Konstantinos I. Gourgoulianis ◽  
Vasileios T. Stavrou
Keyword(s):  
Physical Activity ◽  
Sleep Quality ◽  
Pittsburgh Sleep Quality Index ◽  
Social Activity ◽  
Hemodialysis Patients ◽  
Quality Of Sleep ◽  
Daily Lives ◽  
Stage Renal Disease ◽  
End Stage

Chronic kidney disease significantly impairs patients’ daily lives and worsens their quality of life. The aim of this study was to investigate the physical activity and quality of sleep, during three days (previous day of dialysis, on the day of dialysis and after day of dialysis), in patients with end-stage renal on hemodialysis. 12 hemodialysis patients were included in our study, answered the Pittsburgh Sleep Quality Index (PSQI) questionnaire, and for each patient were used a smart bracelet for three days (day-pre- and posthemodialysis and day at hemodialysis) to record daily physical activity (steps, distance) and estimate the quality of sleep. Results showed differences between three days average of steps and distance and PSQI parameters “…engaging in social activity?” (steps, p=0.006, distance, p=0.006) and “…enthusiasm to get things done?” (steps, p=0.029, distance, p=0.030). Our study suggests interrelationship between sleep quality and physical activity.

scholarly journals Duchenne Smile is Associated with Quality of Life and Survival in Hemodialysis Patients

2020 ◽  
Vol 44 (3) ◽  
pp. 313-325
Author(s):  
Mabel Aoun ◽  
Ghassan Sleilaty ◽  
Leony Antoun ◽  
Racha Dib ◽  
Dania Chelala
Keyword(s):  
Quality Of Life ◽  
Hemodialysis Patients ◽  
Physical Component Score ◽  
Dialysis Patients ◽  
Duchenne Smile ◽  
Health Related Qol ◽  
Health Related ◽  
Stage Renal Disease ◽  
End Stage

Objectives: Hemodialysis is the most used renal replacement modality for end-stage renal disease patients. Dialysis patients are usually assessed for quality of life (QoL) but smiling was never studied. Duchenne smile is a genuine expression of joy, associated with better survival in some groups of the general population. In this study, we aimed to evaluate whether the smile of dialysis patients can predict their QoL and mortality. Methods: All hemodialysis patients in Saint-George Hospital were included in this prospective study. Patients were interviewed using the Health-Related QoL questionnaire and followed for 10 days for smile screening. Those who smiled more than 34% of time were considered as smiling, then followed for death over 2 years. Results: Overall, 71 patients were studied. Duchenne smile was associated with death at 1 and 2 years (HR = 0.194 [95% CI 0.039-0.958], p = .044) but not with sex or diabetes. Smiling showed a statistically significant correlation with older age, fewer hospitalizations, vitality, physical component score, several QoL scores and general health. Conclusions: A simple observation of patients' Duchenne smile by nephrologists in hemodialysis units can give an idea about their QoL and 2-year survival.

scholarly journals Association of Quality of Life, Anxiety, and Depression with Restless Leg Syndrome in the Hemodialysis Patients

2021 ◽  
Author(s):  
Mahjabeen Yaseen ◽  
Furqan Ahmad Jarullah ◽  
Sadia Yaqoob ◽  
Hassan Abdullah Shakeel ◽  
Hamza Maqsood ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Kidney Diseases ◽  
Hemodialysis Patients ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Restless Leg Syndrome ◽  
P Values ◽  
Stage Renal Disease ◽  
End Stage

Abstract ObjectivesRestless Legs Syndrome (RLS) is commonly known to cause morbidity in patients on hemodialysis, making them prone to chronic mental health illnesses such as depression and anxiety, and also adversely impact quality of life. In this study, we examined the association of quality of life, anxiety, and depression with restless leg syndrome in the hemodialysis patients at Karachi Institute of Kidney Diseases. ResultsAbout 26.7% of the participants reported RLS among the sample size Presence of RLS was not associated with quality of life, depression, and anxiety. However, p-values <0.05 were significant for body-mass index (BMI), diabetes mellitus as a cause of end-stage renal disease, and serum albumin levels. Majority (82.5%) of the RLS-diagnosed patients had moderate to severe symptoms with 16 (40%) and 17 (42.5%) clients, respectively.

Aortofemoral Bypass to Bridge End-Stage Renal Disease Patients with Severe Iliac Calcification to Kidney Transplantation

Vascular ◽  
2009 ◽  
Vol 17 (5) ◽  
pp. 269-272 ◽  
Author(s):  
Meritxell Davins ◽  
Secundino Llagostera ◽  
Rocio Jimenez ◽  
Antonio Rosales ◽  
Josep Maria Romero ◽  
...  
Keyword(s):  
Renal Transplantation ◽  
Hemodialysis Patients ◽  
Aortofemoral Bypass ◽  
Lower Survival Rate ◽  
Aortic Bypass ◽  
Stage Renal Disease ◽  
End Stage ◽  
To Receive ◽  
Severe Calcification

Patients undergoing hemodialysis have a lower survival rate than those who receive a kidney transplant. Mortality among hemodialysis patients is approximately 14.5% compared with 1.5% for transplant recipients. One of the exclusion criteria for renal transplant is severe iliac artery calcification. We performed an aortofemoral bypass in these patients to make them eligible for renal transplantation. Eleven patients were selected to receive an aortofemoral bypass. All had severe calcification of iliac arteries. Eight patients required a bypass from the thoracic aorta and two from the infrarenal level. Revascularization was successful in 10 patients. Patency was 100%. Surgery could not be performed in one owing to severe calcification of the femoral artery. One patient died owing to gastrointestinal bleeding. Two patients developed complications; one needed a splenectomy, and the other developed meningitis and paralytic ileus. To date, four patients have received transplants, and the viability of the transplanted kidney is good in all cases. Renal transplantation is the only method known to improve survival and quality of life for hemodialysis patients. We consider that if patients with severe iliac calcification are well informed of the morbidity and mortality risk of an aortic bypass, this intervention can be justified in this setting.

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