scholarly journals Pulse pressure during the initial resuscitative period in patients with septic shock treated with a protocol-driven resuscitation bundle therapy

2020 ◽  
Author(s):  
Sang-Hun Lee ◽  
Youn-Jung Kim ◽  
Gi Na Yu ◽  
Jae Cheon Jeon ◽  
Won Young Kim
Keyword(s):  
Septic Shock ◽  
Pulse Pressure ◽  
Resuscitation Bundle

scholarly journals Pulse pressure variation and adrenal insufficiency in septic shock

Critical Care ◽  
2007 ◽  
Vol 11 (Suppl 2) ◽  
pp. P308
Author(s):  
A Sami ◽  
S Abdellatif ◽  
R Nasri ◽  
H Ksouri ◽  
S Ben Lakhal
Keyword(s):  
Septic Shock ◽  
Adrenal Insufficiency ◽  
Pulse Pressure ◽  
Pulse Pressure Variation ◽  
Pressure Variation

Postoperative Vasodilatory Shock

2020 ◽  
pp. 333-342
Author(s):  
Fiona Roberts ◽  
Alan Gaffney
Keyword(s):  
Septic Shock ◽  
Cardiac Output ◽  
Fluid Resuscitation ◽  
Antimicrobial Therapy ◽  
Pulse Pressure ◽  
Vasodilatory Shock ◽  
First Line ◽  
Treatment Interventions ◽  
Common Cause ◽  
Early Fluid

This chapter discusses vasodilatory shock. The hallmark of vasodilatory shock is hypotension with normal or increased cardiac output. The hyperdynamic circulatory state of vasodilatory shock results in a tachycardia and an increased pulse pressure. Radiological and biochemical investigations can assist with determining the diagnosis of shock. The causes of vasodilatory shock are diverse; they include sepsis, surgical insult, anaphylaxis, and others such as trauma, burns, and pancreatitis. However, sepsis is by far the most common cause of vasodilatory shock. The pathophysiology of vasodilatory shock is also complex and multifactorial. Although still not fully understood, it is widely accepted that it includes activation of several intrinsic vasodilatory pathways and a vascular hyporesponsiveness to vasopressors. Early fluid resuscitation and appropriate antimicrobial therapy are the most crucial treatment interventions in septic shock. Meanwhile, noradrenaline is the first-line vasopressor of choice in septic shock.

Resuscitation Bundle Compliance in Severe Sepsis and Septic Shock

2011 ◽  
Vol 26 (5) ◽  
pp. 304-313 ◽  
Author(s):  
Victor Coba ◽  
Melissa Whitmill ◽  
Roberta Mooney ◽  
H. Mathilda Horst ◽  
Mary-Margaret Brandt ◽  
...  
Keyword(s):  
Septic Shock ◽  
Severe Sepsis ◽  
Bundle Compliance ◽  
Sepsis And Septic Shock ◽  
Resuscitation Bundle

scholarly journals Effects of sepsis resuscitation bundle in cirrhotic patients with septic shock

Critical Care ◽  
2010 ◽  
Vol 14 (Suppl 1) ◽  
pp. P403
Author(s):  
L Rinaldi ◽  
E Ferrari ◽  
D Trevisan ◽  
L Donno ◽  
M Girardis
Keyword(s):  
Septic Shock ◽  
Cirrhotic Patients ◽  
Resuscitation Bundle

Outcome of delayed resuscitation bundle achievement in emergency department patients with septic shock

2014 ◽  
Vol 9 (6) ◽  
pp. 671-676 ◽  
Author(s):  
Chang Hwan Sohn ◽  
Seung Mok Ryoo ◽  
Dong Woo Seo ◽  
Jae Ho Lee ◽  
Bum Jin Oh ◽  
...  
Keyword(s):  
Emergency Department ◽  
Septic Shock ◽  
Emergency Department Patients ◽  
Resuscitation Bundle

scholarly journals Compliance and barriers to implementing the sepsis resuscitation bundle for patients developing septic shock in the general medical wards

2012 ◽  
Vol 111 (2) ◽  
pp. 77-82 ◽  
Author(s):  
Yao-Wen Kuo ◽  
Hou-Tai Chang ◽  
Pei-Chen Wu ◽  
Yen-Fu Chen ◽  
Ching-Kai Lin ◽  
...  
Keyword(s):  
Septic Shock ◽  
Medical Wards ◽  
Resuscitation Bundle

Protocol-Based Resuscitation Bundle to Improve Outcomes in Septic Shock Patients

2016 ◽  
Vol 44 (12) ◽  
pp. 2123-2130 ◽  
Author(s):  
Michael P. Thompson ◽  
Mathew J. Reeves ◽  
Brittany L. Bogan ◽  
Bruno DiGiovine ◽  
Patricia J. Posa ◽  
...  
Keyword(s):  
Septic Shock ◽  
Resuscitation Bundle

Body Composition Analysis in Septic Shock Patients Receiving Protocol-Driven Resuscitation Bundle Therapy: A Prospective Observational Study

2021 ◽  
Author(s):  
Bora Chae ◽  
Yo Sep Shin ◽  
Seok-In Hong ◽  
Sang Min Kim ◽  
Youn-Jung Kim ◽  
...  
Keyword(s):  
Septic Shock ◽  
Body Composition ◽  
Impedance Analysis ◽  
Composition Analysis ◽  
Body Composition Analysis ◽  
Total Body ◽  
Poor Outcomes ◽  
The Relationship ◽  
Mean Time ◽  
Resuscitation Bundle

Abstract Background: Bio-electrical impedance analysis (BIA) is a rapid, simple, and noninvasive tool for assessing volume status in various diseases. Body composition analysis using BIA may identify factors associated with poor outcomes in critically ill patients. Little is known, however, about the relationship between the results of body composition analysis in the emergency department (ED) and mortality in septic shock patients.Objectives: This study assessed the association between parameters identified by body composition analysis and mortality in patients with septic shock who underwent protocol-driven resuscitation bundle therapy in the ED.Methods: Data were prospectively collected on adult patients with septic shock who underwent protocol-driven resuscitation bundle therapy between December 2019 and December 2020. Body composition was determined in the ED using BIA with the patient in the supine position. Septic shock was defined by sepsis-3 criteria, and the primary outcome was 30-day mortality. Results: The study included 218 patients, of whom 58 (26.6%) died within 30 days. The mean time from ED admission to the measurement of body composition was 5.4 hours. The average ratio of extracellular water (ECW) to total body water (TBW) was significantly higher in non-survivors than in survivors (0.412 vs. 0.400, p=0.001). The optimal ECW/TBW cutoff for predicting 30-day mortality was 0.40, with mortality rates being significantly higher in patients with ECW/TBW >0.4 than in patients with ECW/TBW≦0.4 (37.8% vs. 17.5%, p=0.001). Multivariate analysis showed that ECW/TBW >0.4 (odds ratio [OR], 2.11; 95% confidence interval [CI], 1.05–4.23, p = 0.036), active cancer (OR, 2.39; 95% CI, 1.06–5.38, p=0.036), prothrombin time (OR, 2.77; 95% CI, 1.29–5.93, p=0.009), and initial lactate level (OR, 1.15; 95% CI, 1.03–1.28, p=0.010) were significantly associated with 30-day mortality.Conclusions: The ECW/TBW>0.40 is the only body composition parameter associated with 30-day mortality in patients with septic shock.

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