Body Composition Analysis in Septic Shock Patients Receiving Protocol-Driven Resuscitation Bundle Therapy: A Prospective Observational Study

2021 ◽  
Author(s):  
Bora Chae ◽  
Yo Sep Shin ◽  
Seok-In Hong ◽  
Sang Min Kim ◽  
Youn-Jung Kim ◽  
...  
Keyword(s):  
Septic Shock ◽  
Body Composition ◽  
Impedance Analysis ◽  
Composition Analysis ◽  
Body Composition Analysis ◽  
Total Body ◽  
Poor Outcomes ◽  
The Relationship ◽  
Mean Time ◽  
Resuscitation Bundle

Abstract Background: Bio-electrical impedance analysis (BIA) is a rapid, simple, and noninvasive tool for assessing volume status in various diseases. Body composition analysis using BIA may identify factors associated with poor outcomes in critically ill patients. Little is known, however, about the relationship between the results of body composition analysis in the emergency department (ED) and mortality in septic shock patients.Objectives: This study assessed the association between parameters identified by body composition analysis and mortality in patients with septic shock who underwent protocol-driven resuscitation bundle therapy in the ED.Methods: Data were prospectively collected on adult patients with septic shock who underwent protocol-driven resuscitation bundle therapy between December 2019 and December 2020. Body composition was determined in the ED using BIA with the patient in the supine position. Septic shock was defined by sepsis-3 criteria, and the primary outcome was 30-day mortality. Results: The study included 218 patients, of whom 58 (26.6%) died within 30 days. The mean time from ED admission to the measurement of body composition was 5.4 hours. The average ratio of extracellular water (ECW) to total body water (TBW) was significantly higher in non-survivors than in survivors (0.412 vs. 0.400, p=0.001). The optimal ECW/TBW cutoff for predicting 30-day mortality was 0.40, with mortality rates being significantly higher in patients with ECW/TBW >0.4 than in patients with ECW/TBW≦0.4 (37.8% vs. 17.5%, p=0.001). Multivariate analysis showed that ECW/TBW >0.4 (odds ratio [OR], 2.11; 95% confidence interval [CI], 1.05–4.23, p = 0.036), active cancer (OR, 2.39; 95% CI, 1.06–5.38, p=0.036), prothrombin time (OR, 2.77; 95% CI, 1.29–5.93, p=0.009), and initial lactate level (OR, 1.15; 95% CI, 1.03–1.28, p=0.010) were significantly associated with 30-day mortality.Conclusions: The ECW/TBW>0.40 is the only body composition parameter associated with 30-day mortality in patients with septic shock.

scholarly journals Extracellular Water to Total Body Water Ratio in Septic Shock Patients Receiving Protocol-Driven Resuscitation Bundle Therapy

2021 ◽  
Vol 10 (13) ◽  
pp. 2917
Author(s):  
Bora Chae ◽  
Yo Sep Shin ◽  
Seok-In Hong ◽  
Sang Min Kim ◽  
Youn-Jung Kim ◽  
...  
Keyword(s):  
Septic Shock ◽  
Body Composition ◽  
Total Body Water ◽  
Altered Mental Status ◽  
Body Water ◽  
Composition Analysis ◽  
Extracellular Water ◽  
Body Composition Analysis ◽  
Total Body ◽  
Resuscitation Bundle

(1) Bio-electrical impedance analysis (BIA) is a rapid, simple, and noninvasive tool for evaluating the metabolic status and for assessing volume status in critically ill patients. Little is known, however, the prognostic value of body composition analysis in septic shock patients. This study assessed the association between parameters by body composition analysis and mortality in patients with septic shock in the emergency department (ED). (2) Data were prospectively collected on adult patients with septic shock who underwent protocol-driven resuscitation bundle therapy between December 2019 and January 2021. The primary outcome was 30-day mortality. (3) The study included 261 patients, the average ratio of extracellular water (ECW) to total body water (TBW) was significantly higher in non-survivors than in survivors (0.414 vs. 0.401, p < 0.001). Multivariate analysis showed that ECW/TBW ≥ 0.41 (odds ratio (OR), 4.62; 95% confidence interval (CI), 2.31–9.26, p < 0.001), altered mental status (OR, 2.88; 95% CI, 1.28–6.46, p = 0.010), and lactate level (OR, 1.24; 95% CI, 1.12–1.37, p < 0.001) were significantly associated with 30-day mortality in patients with septic shock. (4) ECW/TBW ≥ 0.41 may be associated with 30-day mortality in patients with septic shock receiving protocol-driven resuscitation bundle therapy in the ED.

scholarly journals Ichthyometry and electrical bioimpedance analysis to estimate the body composition of tambatinga

2014 ◽  
Vol 44 (2) ◽  
pp. 279-286 ◽  
Author(s):  
Francisco Teixeira Andrade ◽  
Márvio Lobão Teixeira de Abreu ◽  
João Batista Lopes ◽  
Agustinho Valente de Figueiredo ◽  
Maria de Nazaré Bona Alencar Araripe ◽  
...  
Keyword(s):  
Body Composition ◽  
Water Content ◽  
Correlation Coefficients ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
The Body ◽  
Composition Analysis ◽  
Average Weight ◽  
Electrical Bioimpedance ◽  
The Relationship

Body composition analysis is relevant to characterize the nutritional requirements and finishing phase of fish. The aim of this study was to investigate the relationship between ichthyometric (weight, total and standard length, density and yields), bromatological (fat, protein, ash and water content) and bioelectrical-impedance-analysis (BIA) (resistance, reactance, phase angle and composition indexes) variables in the hybrid tambatinga (Colossoma macropomum × Piaractus brachypomus). In a non-fertilized vivarium, 520 juveniles were housed and fed commercial rations. Then, 136 days after hatching (DAH), 15 fish with an average weight of 37.69 g and average total length of 12.96 cm were randomly chosen, anesthetized (eugenol) and subjected to the first of fourteen fortnightly assessments (BIA and biometry). After euthanasia, the following parts were weighed: whole carcass with the head, fillet, and skin (WC); fillet with skin (FS); and the remainder of the carcass with the head (CH). Together, FS and CH were ground and homogenized for the bromatological analyses. Estimates of the body composition and yields of tambatinga, with models including ichthyometric and BIA variables, showed correlation coefficients ranging from 0.81 (for the FS yield) to 1,00 (for the total ash). Similarly, models that included only BIA variables had correlation coefficients ranging from 0.81 (FS and CH yields) to 0.98 (for the total ash). Therefore, in tambatinga, the BIA technique allows the estimation of the yield of the fillet with skin and the body composition (water content, fat, ash, and protein). The best models combine ichthyometric and BIA variables.

SUN-PO014: Interest of Body Composition Analysis in CT in Cirrhotic Patients with Septic Shock

2019 ◽  
Vol 38 ◽  
pp. S63
Author(s):  
C. Lemaitre ◽  
M. Devilder ◽  
R. Modzelewski ◽  
M. Dolores ◽  
H. Montialoux ◽  
...  
Keyword(s):  
Septic Shock ◽  
Body Composition ◽  
Composition Analysis ◽  
Body Composition Analysis ◽  
Cirrhotic Patients

Comparison of three techniques for body composition analysis in cystic fibrosis

1993 ◽  
Vol 75 (1) ◽  
pp. 162-166 ◽  
Author(s):  
L. C. Lands ◽  
C. Gordon ◽  
O. Bar-Or ◽  
C. J. Blimkie ◽  
R. M. Hanning ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Body Composition ◽  
Nutritional Assessment ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Composition Analysis ◽  
Dual Photon Absorptiometry ◽  
Regression Equations ◽  
Body Composition Analysis ◽  
And Control

Body composition analysis is an important component of nutritional assessment in cystic fibrosis (CF). No gold standard of measurement exists, and techniques applicable to healthy populations may be unsuitable for CF patients. We assessed lean body mass (LBM) in 12 children with CF by skinfold (SK) measurements, bioelectrical impedance analysis (BIA), and dual-photon absorptiometry (DPA) and repeated these measures in 10 subjects 6 mo later. SK and DPA measures in eight older CF patients and eight healthy controls were compared to evaluate any effect of disease on estimates of LBM by use of DPA. Good agreement between the measures was seen at baseline and 6 mo by use of concordance plots. However, the limits of agreement between measures ranged up to 19% of SK-derived LBM measures (baseline: SK and DPA, 2.63 to -3.93 kg; SK and BIA, 2.36 to -1.24 kg; BIA and DPA, 1.88 to -4.28 kg; 6 mo: SK and DPA, 2.10 to -3.58 kg; SK and BIA, 6.28 to -5.49 kg; BIA and DPA, 5.53 to -7.79 kg). The change in LBM over 6 mo did not correlate among the three measures. Only BIA change in LBM correlated with weight change (r = 0.716, P < 0.02), probably due to the inclusion of weight in the regression equations for determining LBM from impedance. The relationship between SK and DPA measures did not differ between the CF and control groups, suggesting that there was no effect of disease on the DPA measure. The results suggest that none of these methods is precise enough to follow short-term changes in the nutritional status of CF patients longitudinally.

Body composition analysis of cachectic rabbits by total body electrical conductivity

1998 ◽  
Vol 32 (3) ◽  
pp. 190-193 ◽  
Author(s):  
Tomoyo Yasui ◽  
Osamu Ishiko ◽  
Toshiyuki Sumi ◽  
Ken‐ichi Honda ◽  
Kouzo Hirai ◽  
...  
Keyword(s):  
Electrical Conductivity ◽  
Body Composition ◽  
Composition Analysis ◽  
Body Composition Analysis ◽  
Total Body

Estimation of human body composition by electrical impedance methods: a comparative study

1985 ◽  
Vol 58 (5) ◽  
pp. 1565-1571 ◽  
Author(s):  
K. R. Segal ◽  
B. Gutin ◽  
E. Presta ◽  
J. Wang ◽  
T. B. Van Itallie
Keyword(s):  
Body Composition ◽  
Human Body ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Prediction Equations ◽  
Uniform Current ◽  
Obese Subjects ◽  
Total Body ◽  
The Relationship ◽  
Human Body Composition

This study 1) further validated the relationship between total body electrical conductivity (TOBEC) and densitometrically determined lean body mass (LBMd) and 2) compared with existing body composition techniques (densitometry, total body water, total body potassium, and anthropometry) two new electrical methods for the estimation of LBM: TOBEC, a uniform current induction method, and bioelectrical impedance analysis (BIA), a localized current injection method. In a sample of 75 male and female subjects ranging from 4.9 to 54.9% body fat the correlation between LBMd and LBM predicted from TOBEC by use of a previously developed regression equation was extremely strong (r = 0.962), thus confirming the validity of the TOBEC method. LBM predicted from BIA by use of prediction equations provided with the instrument also correlated with LBMd (r = 0.912) but overestimated LBM compared with LBMd in obese subjects. However, no such systematic error was apparent when new prediction equations derived from this heterogeneous sample of subjects were applied. Thus the TOBEC and BIA methods, which are based on the differing electrical properties of lean tissue and fat and which are convenient, rapid, and safe, correlate well with more cumbersome human body composition techniques.

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