Protective Effect of Zanthoxylum nitidum Bark in Chemical and Stress Induced Gastric Mucosal Lesions in Male Albino Rats

2012 ◽  
Vol 8 (5) ◽  
pp. 450-454 ◽  
Author(s):  
Sanjib Bhattachar ◽  
K. Zaman
1989 ◽  
Vol 51 (4) ◽  
pp. 569-571
Author(s):  
Motonobu MURAKAMI ◽  
Jung Keun YOO ◽  
Sanae TERAMURA ◽  
Ko YAMAMOTO ◽  
Hiroshi SAITA ◽  
...  

1994 ◽  
Vol 64 ◽  
pp. 87
Author(s):  
Hideshi Omura ◽  
Kazuhisa Maeda ◽  
Masahiko Ishimura ◽  
Yoshinori Kamisaki ◽  
Tadao Itoh

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Tadashi Nakamura ◽  
Yoshiji Ohta ◽  
Kumiko Ikeno ◽  
Koji Ohashi ◽  
Takeyuki Ikeno

The present study was conducted to clarify the protective effect of Brazilian propolis ethanol extract (BPEE) against stress-induced gastric mucosal lesions in rats. The protective effect of BPEE against gastric mucosal lesions in male Wistar rats exposed to water-immersion restraint stress (WIRS) for 6 h was compared between its repeated preadministration (50 mg/kg/day, 7 days) and its single preadministration (50 mg/kg). The repeated BPEE preadministration attenuated WIRS-induced gastric mucosal lesions and gastric mucosal oxidative stress more largely than the single BPEE preadministration. In addition, the repeated BPEE preadministration attenuated neutrophil infiltration in the gastric mucosa of rats exposed to WIRS. The protective effect of the repeated preadministration of BPEE against WIRS-induced gastric mucosal lesions was similar to that of a single preadministration of vitamin E (250 mg/kg) in terms of the extent and manner of protection. From these findings, it is concluded that BPEE preadministered in a repeated manner protects against gastric mucosal lesions in rats exposed to WIRS more effectively than BPEE preadministered in a single manner possibly through its antioxidant and anti-inflammatory actions.


Life Sciences ◽  
1990 ◽  
Vol 47 (12) ◽  
pp. 1031-1036 ◽  
Author(s):  
Harunobu Amagase ◽  
Teruo Murakami ◽  
Masafumi Misaki ◽  
Yutaka Higashi ◽  
Michiyasu Ushijima ◽  
...  

2003 ◽  
Vol 93 (3) ◽  
pp. 337-346 ◽  
Author(s):  
Yoshiji Ohta ◽  
Takashi Kobayashi ◽  
Kazuo Inui ◽  
Junji Yoshino ◽  
Saburo Nakazawa

2021 ◽  
Vol 53 (1) ◽  
pp. 1696-1708
Author(s):  
Prakash Chandra Gupta ◽  
Ashish Kar ◽  
Nisha Sharma ◽  
Prashant Kumar Singh ◽  
Naba Kumar Goswami ◽  
...  

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