The Precision of a New Anterior Segment Optical Coherence Tomographer and Its Comparison With a Swept-Source OCT-Based Optical Biometer in Patients With Cataract

2021 ◽  
Vol 37 (9) ◽  
pp. 616-622
Author(s):  
Qinmei Wang ◽  
Min Chen ◽  
Rui Ning ◽  
Giacomo Savini ◽  
Yiran Wang ◽  
...  
2021 ◽  
pp. bjophthalmol-2020-318334
Author(s):  
Wei Wang ◽  
Jiaqing Zhang ◽  
Xiaoxun Gu ◽  
Xiaoting Ruan ◽  
Xiaoyun Chen ◽  
...  

Background/aimsThe primary objective is to quantify the lens nuclear opacity using swept-source anterior segment optical coherence tomography (SS-ASOCT) and to evaluate its correlations with Lens Opacities Classification System III (LOCS-III) system and surgical parameters. The secondary objective is to assess the diagnostic performance for hard nuclear cataract.MethodsThis cross-sectional study included 1222 patients eligible for cataract surgery (1222 eyes). The latest SS-ASOCT (CASIA-2) was used to obtain high-resolution lens images, and the average nuclear density (AND) and maximum nuclear density (MND) were measured by a custom ImageJ software. Spearman’s correlations analysis was used to assess associations of AND/MND with LOCS-III nuclear scores, visual acuity and surgical parameters. The subjects were then split randomly (9:1) into the training dataset and validating dataset. Receiver operating characteristic curves and calibration curves were constructed for the classification on hard nuclear cataract.ResultsThe AND and MND from SS-ASOCT images were significantly correlated with nuclear colour scores (AND: r=0.716; MND: r=0.660; p<0.001) and nuclear opalescence scores (AND: r=0.712; MND: r=0.655; p<0.001). The AND by SS-ASOCT images had the highest values of Spearman’s r for preoperative corrected distance visual acuity (r=0.3131), total ultrasonic time (r=0.3481) and cumulative dissipated energy (r=0.4265). The nuclear density had good performance in classifying hard nuclear cataract, with area under the curves of 0.859 (0.831–0.886) for AND and 0.796 (0.768–0.823) for MND.ConclusionObjective and quantitative evaluation of the lens nuclear density using SS-ASOCT images enable accurate diagnosis of hard nuclear cataract.


Cornea ◽  
2019 ◽  
Vol 38 (1) ◽  
pp. 93-97 ◽  
Author(s):  
Khaled Abdelazeem ◽  
Mohamed Sharaf ◽  
Mohamed G. A. Saleh ◽  
Ahmed M. Fathalla ◽  
Wael Soliman

2020 ◽  
Vol 13 (2) ◽  
pp. 106-112 ◽  
Author(s):  
Se-Joon Oh ◽  
Il-Woo Lee ◽  
Soo-Geun Wang ◽  
Soo-Keun Kong ◽  
Hong-Ki Kim ◽  
...  

Objectives. This study aimed to investigate whether optical coherence tomography (OCT) provides useful information about the microstructures of the middle and inner ear via extratympanic approach and thereby could be utilized as an alternative diagnostic technology in ear imaging.Methods. Five rats and mice were included, and the swept-source OCT system was applied to confirm the extent of visibility of the middle and inner ear and measure the length or thickness of the microstructures in the ear. The cochlea was subsequently dissected following OCT and histologically evaluated to compare with the OCT images.Results. The middle ear microstructures such as ossicles, stapedial artery and oval window through the tympanic membrane with the OCT could be confirmed in both rats and mice. It was also possible to obtain the inner ear images such as each compartment of the cochlea in the mice, but the bone covering bulla needed to be removed to visualize the inner ear structures in the rats which had thicker bulla. The bony thickness covering the cochlea could be measured, which showed no significant differences between OCT and histologic image at all turns of cochlea.Conclusion. OCT has been shown a promising technology to assess real-time middle and inner ear microstructures noninvasively with a high-resolution in the animal model. Therefore, OCT could be utilized to provide additional diagnostic information about the diseases of the middle and inner ear.


2012 ◽  
Vol 3 (11) ◽  
pp. 2733 ◽  
Author(s):  
Ireneusz Grulkowski ◽  
Jonathan J. Liu ◽  
Benjamin Potsaid ◽  
Vijaysekhar Jayaraman ◽  
Chen D. Lu ◽  
...  

Optical coherence tomography (OCT), which is in use for about 20 years, facilitated the evaluation of the vitreoretinal interface, improved our understanding of its pathologic processes, and paved the way to new treatment approaches. By order of appearance, time-domain, spectral-domain, and swept-source OCT technologies redefined vitreoretinal interface disorders and their treatment modalities.


2013 ◽  
Vol 50 (8) ◽  
pp. 080014
Author(s):  
史国华 Shi Guohua ◽  
王飞 Wang Fei ◽  
李喜琪 Li Xiqi ◽  
孙兴怀 Sun Xinghuai ◽  
姜春晖 Jiang Chunhui ◽  
...  

2019 ◽  
Vol 28 (5) ◽  
pp. 433-439
Author(s):  
Akiko Narita ◽  
Yuki Morizane ◽  
Tomoe Miyake ◽  
Kae Sugihara ◽  
Tomoko Ishikawa ◽  
...  

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