Thoracic Aortic Disease

Author(s):  
Berhane Worku ◽  
Leonard Girardi

Thoracic aortic disease most commonly presents in the form of aneurysmal dilation or dissection of the ascending or descending thoracic aorta, most commonly secondary to degenerative disease and hypertension. Several genetic connective tissue disorders are commonly associated as well. Treatment is focused on blood pressure control and surgical repair. Surgical repair of thoracic aortic disease presents unique risks, including neurologic injury involving the brain or spinal cord, and several adjuncts are available to mitigate against this risk. This chapter discusses commonly associated risk factors, preoperative testing, surgical repair, and postoperative management of thoracic aortic disease along with strategies for minimizing neurologic injury.

Author(s):  
Berhane Worku ◽  
Leonard Girardi

Thoracic aortic disease most commonly presents in the form of aneurysmal dilation or dissection of the ascending or descending thoracic aorta, most commonly secondary to degenerative disease and hypertension. Several genetic connective tissue disorders are commonly associated as well. Treatment is focused on blood pressure control and surgical repair. Surgical repair of thoracic aortic disease presents unique risks, including neurologic injury involving the brain or spinal cord, and several adjuncts are available to mitigate against this risk. This chapter discusses commonly associated risk factors, preoperative testing, surgical repair, and postoperative management of thoracic aortic disease along with strategies for minimizing neurologic injury.


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pp. 255-261
Author(s):  
Won-Young Lee ◽  
Jae Suk Yoo ◽  
Joon Bum Kim ◽  
Sung-Ho Jung ◽  
Suk Jung Choo ◽  
...  

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pp. 800-804 ◽  
Author(s):  
Xiu-Juan Jiang ◽  
Zhan-Lan Liu ◽  
Qiang She ◽  
Yue-Hui Ying ◽  
Jing Huang ◽  
...  

Author(s):  
Assen Jablensky

Epidemiological research into schizophrenia has a long and productive history over many decades, since the formulation of the disease concept by Emil Kraepelin in 1896. As a critical counterpart to clinical and biological research, its focus is on the population frequency and distribution of incidence, prevalence, course, and outcome, and the associated risk factors. This chapter presents an overview of the historical landmarks of the epidemiology of schizophrenia, its progress over the years, and the state of current knowledge. It highlights the challenges for its future directions of this research, including the question of whether primary or secondary prevention of the disorder will eventually be possible. The unprecedented growth of basic knowledge about the brain and the human genome opens up novel perspectives in the study of complex disorders, such as schizophrenia, which integrate concepts and tools of genetics, neuroscience, and epidemiology.


2012 ◽  
Vol 17 (6) ◽  
pp. 235-242 ◽  
Author(s):  
Marjorie Bastien ◽  
François Dagenais ◽  
Éric Dumont ◽  
Nathalie Vadeboncoeur ◽  
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...  

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Vol 55 (10) ◽  
pp. 986-1001 ◽  
Author(s):  
Davy Cheng ◽  
Janet Martin ◽  
Hani Shennib ◽  
Joel Dunning ◽  
Claudio Muneretto ◽  
...  

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