Mining Electronic Health Records to Guide and Support Clinical Decision Support Systems

Author(s):  
Jitendra Jonnagaddala ◽  
Hong-Jie Dai ◽  
Pradeep Ray ◽  
Siaw-Teng Liaw

Clinical decision support systems require well-designed electronic health record (EHR) systems and vice versa. The data stored or captured in EHRs are diverse and include demographics, billing, medications, and laboratory reports; and can be categorized as structured, semi-structured and unstructured data. Various data and text mining techniques have been used to extract these data from EHRs for use in decision support, quality improvement and research. Mining EHRs has been used to identify cohorts, correlated phenotypes in genome-wide association studies, disease correlations and risk factors, drug-drug interactions, and to improve health services. However, mining EHR data is a challenge with many issues and barriers. The aim of this chapter is to discuss how data and text mining techniques may guide and support the building of improved clinical decision support systems.

2017 ◽  
pp. 184-201 ◽  
Author(s):  
Jitendra Jonnagaddala ◽  
Hong-Jie Dai ◽  
Pradeep Ray ◽  
Siaw-Teng Liaw

Clinical decision support systems require well-designed electronic health record (EHR) systems and vice versa. The data stored or captured in EHRs are diverse and include demographics, billing, medications, and laboratory reports; and can be categorized as structured, semi-structured and unstructured data. Various data and text mining techniques have been used to extract these data from EHRs for use in decision support, quality improvement and research. Mining EHRs has been used to identify cohorts, correlated phenotypes in genome-wide association studies, disease correlations and risk factors, drug-drug interactions, and to improve health services. However, mining EHR data is a challenge with many issues and barriers. The aim of this chapter is to discuss how data and text mining techniques may guide and support the building of improved clinical decision support systems.


2017 ◽  
Vol 56 (03) ◽  
pp. 238-247 ◽  
Author(s):  
Georgy Kopanitsa

SummaryBackground: The efficiency and acceptance of clinical decision support systems (CDSS) can increase if they reuse medical data captured during health care delivery. High heterogeneity of the existing legacy data formats has become the main barrier for the reuse of data. Thus, we need to apply data modeling mechanisms that provide standardization, transformation, accumulation and querying medical data to allow its reuse.Objectives: In this paper, we focus on the interoperability issues of the hospital information systems (HIS) and CDSS data integration.Materials and Methods: Our study is based on the approach proposed by Marcos et al. where archetypes are used as a standardized mechanism for the interaction of a CDSS with an electronic health record (EHR). We build an integration tool to enable CDSSs collect data from various institutions without a need for modifications in the implementation. The approach implies development of a conceptual level as a set of archetypes representing concepts required by a CDSS.Results: Treatment case data from Regional Clinical Hospital in Tomsk, Russia was extracted, transformed and loaded to the archetype database of a clinical decision support system. Test records’ normalization has been performed by defining transformation and aggregation rules between the EHR data and the archetypes. These mapping rules were used to automatically generate openEHR compliant data. After the transformation, archetype data instances were loaded into the CDSS archetype based data storage. The performance times showed acceptable performance for the extraction stage with a mean of 17.428 s per year (3436 case records). The transformation times were also acceptable with 136.954 s per year (0.039 s per one instance). The accuracy evaluation showed the correctness and applicability of the method for the wide range of HISes. These operations were performed without interrupting the HIS workflow to prevent the HISes from disturbing the service provision to the users.Conclusions: The project results have proven that archetype based technologies are mature enough to be applied in routine operations that require extraction, transformation, loading and querying medical data from heterogeneous EHR systems. Inference models in clinical research and CDSS can benefit from this by defining queries to a valid data set with known structure and constraints. The standard based nature of the archetype approach allows an easy integration of CDSSs with existing EHR systems.


2014 ◽  
Vol 59 (suppl_3) ◽  
pp. S122-S133 ◽  
Author(s):  
Graeme N. Forrest ◽  
Trevor C. Van Schooneveld ◽  
Ravina Kullar ◽  
Lucas T. Schulz ◽  
Phu Duong ◽  
...  

1993 ◽  
Vol 32 (01) ◽  
pp. 12-13 ◽  
Author(s):  
M. A. Musen

Abstract:Response to Heathfield HA, Wyatt J. Philosophies for the design and development of clinical decision-support systems. Meth Inform Med 1993; 32: 1-8.


2006 ◽  
Vol 45 (05) ◽  
pp. 523-527 ◽  
Author(s):  
A. Abu-Hanna ◽  
B. Nannings

Summary Objectives: Decision Support Telemedicine Systems (DSTS) are at the intersection of two disciplines: telemedicine and clinical decision support systems (CDSS). The objective of this paper is to provide a set of characterizing properties for DSTSs. This characterizing property set (CPS) can be used for typing, classifying and clustering DSTSs. Methods: We performed a systematic keyword-based literature search to identify candidate-characterizing properties. We selected a subset of candidates and refined them by assessing their potential in order to obtain the CPS. Results: The CPS consists of 14 properties, which can be used for the uniform description and typing of applications of DSTSs. The properties are grouped in three categories that we refer to as the problem dimension, process dimension, and system dimension. We provide CPS instantiations for three prototypical applications. Conclusions: The CPS includes important properties for typing DSTSs, focusing on aspects of communication for the telemedicine part and on aspects of decisionmaking for the CDSS part. The CPS provides users with tools for uniformly describing DSTSs.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
S M Jansen-Kosterink ◽  
M Cabrita ◽  
I Flierman

Abstract Background Clinical Decision Support Systems (CDSSs) are computerized systems using case-based reasoning to assist clinicians in making clinical decisions. Despite the proven added value to public health, the implementation of CDSS clinical practice is scarce. Particularly, little is known about the acceptance of CDSS among clinicians. Within the Back-UP project (Project Number: H2020-SC1-2017-CNECT-2-777090) a CDSS is developed with prognostic models to improve the management of Neck and/or Low Back Pain (NLBP). Therefore, the aim of this study is to present the factors involved in the acceptance of CDSSs among clinicians. Methods To assess the acceptance of CDSSs among clinicians we conducted a mixed method analysis of questionnaires and focus groups. An online questionnaire with a low-fidelity prototype of a CDSS (TRL3) was sent to Dutch clinicians aimed to identify the factors influencing the acceptance of CDSSs (intention to use, perceived threat to professional autonomy, trusting believes and perceived usefulness). Next to this, two focus groups were conducted with clinicians addressing the general attitudes towards CDSSs, the factors determining the level of acceptance, and the conditions to facilitate use of CDSSs. Results A pilot-study of the online questionnaire is completed and the results of the large evaluation are expected spring 2020. Eight clinicians participated in two focus groups. After being introduced to various types of CDSSs, participants were positive about the value of CDSS in the care of NLBP. The clinicians agreed that the human touch in NLBP care must be preserved and that CDSSs must remain a supporting tool, and not a replacement of their role as professionals. Conclusions By identifying the factors hindering the acceptance of CDSSs we can draw implications for implementation of CDSSs in the treatment of NLBP.


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