Aortic Valvular Disease

Author(s):  
Eric Leo Sarin ◽  
Vinod H. Thourani

Broadly speaking, pathology is categorized as being primarily related to valvular stenosis (AS) or regurgitation (AR), but a diseased valve may often exhibit both. The predilection of degenerative disease of the aortic valve, particularly stenosis, for the elderly has resulted in a steadily increasing prevalence as the population ages. As general life expectancy increases in the United States and other western countries, surgery to correct aortic valve disease will increase. As more elderly patients with more comorbidities present for surgery their intraoperative and perioperative care will become more complex. This chapter discusses ways for the practicing intensivist to facilitate identification and treatment in the immediate peri-operative period.

Author(s):  
Eric Leo Sarin ◽  
Vinod H. Thourani

Broadly speaking, pathology is categorized as being primarily related to valvular stenosis (AS) or regurgitation (AR), but a diseased valve may often exhibit both. The predilection of degenerative disease of the aortic valve, particularly stenosis, for the elderly has resulted in a steadily increasing prevalence as the population ages. As general life expectancy increases in the United States and other western countries, surgery to correct aortic valve disease will increase. As more elderly patients with more comorbidities present for surgery their intraoperative and perioperative care will become more complex. This chapter discusses ways for the practicing intensivist to facilitate identification and treatment in the immediate peri-operative period.


2015 ◽  
Vol 116 (1) ◽  
pp. 132-141 ◽  
Author(s):  
Apurva O. Badheka ◽  
Vikas Singh ◽  
Nileshkumar J. Patel ◽  
Shilpkumar Arora ◽  
Nilay Patel ◽  
...  

Aorta ◽  
2021 ◽  
Author(s):  
Igor Vendramin ◽  
Uberto Bortolotti ◽  
Davide Nunzio De Manna ◽  
Andrea Lechiancole ◽  
Sandro Sponga ◽  
...  

AbstractSimultaneous replacement of the ascending aorta and aortic valve has always been a challenging procedure. Introduction of composite conduits, through various ingenious procedures and their modifications, has changed the outlook of patients with aortic valve disease and ascending aorta pathology. In the past 70 years, progress of surgical techniques and prosthetic materials has allowed such patients to undergo radical procedures providing excellent early and long-term results in both young and elderly patients. This article aims to review the most important technical advances in the treatment of aortic valve disease and ascending aorta aneurysms recognizing the important contributions in this field.


2014 ◽  
Vol 25 (5) ◽  
pp. 244-248 ◽  
Author(s):  
Ebuzer Aydin ◽  
Ozge Altas Yerlikhan ◽  
Behzat Tuzun ◽  
Yucel Ozen ◽  
Sabit Sarikaya ◽  
...  

Circulation ◽  
2012 ◽  
Vol 126 (13) ◽  
pp. 1621-1629 ◽  
Author(s):  
J. Matthew Brennan ◽  
Fred H. Edwards ◽  
Yue Zhao ◽  
Sean M. O'Brien ◽  
Pamela S. Douglas ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-16 ◽  
Author(s):  
Katie L. Losenno ◽  
Robert L. Goodman ◽  
Michael W. A. Chu

The bicuspid aortic valve is the most common congenital cardiac anomaly in developed nations. The abnormal bicuspid morphology of the aortic valve results in valvular dysfunction and subsequent hemodynamic derangements. However, the clinical presentation of bicuspid aortic valve disease remains quite heterogeneous with patients presenting from infancy to late adulthood with variable degrees of valvular stenosis and insufficiency and associated abnormalities including aortic coarctation, hypoplastic left heart structures, and ascending aortic dilatation. Emerging evidence suggests that the heterogeneous presentation of bicuspid aortic valve phenotypes may be a more complex matter related to congenital, genetic, and/or connective tissue abnormalities. Optimal management of patients with BAV disease and associated ascending aortic aneurysms often requires a thoughtful approach, carefully assessing various risk factors of the aortic valve and the aorta and discerning individual indications for ongoing surveillance, medical management, and operative intervention. We review current concepts of anatomic classification, pathophysiology, natural history, and clinical management of bicuspid aortic valve disease with associated ascending aortic aneurysms.


1988 ◽  
Vol 46 (3) ◽  
pp. 264-269 ◽  
Author(s):  
Luis N. Bessone ◽  
Dennis F. Pupello ◽  
Stephen P. Hiro ◽  
Enrique Lopez-Cuenca ◽  
M.S. Glatterer ◽  
...  

Author(s):  
John G. Webb ◽  
Fabian Nietlispach

Aortic stenosis (AS) is the most common valvular heart disease for which patients undergo valve replacement. Although the condition may develop in mid-life in association with a congenitally bicuspid valve, AS is for the most part a disease of the elderly, as demonstrated by a recent community-based study in the United States which reported a prevalence in those older than 75 years of age of 4.6%. Medically treated severe symptomatic AS has been associated with predictable clinical deterioration and a poor survival, reportedly averaging 2–3 years after the onset of symptoms.


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