Noninfectious Corneal Disorders

2022 ◽  
pp. 253-287

This chapter discusses noninfectious corneal disorders, caused by an immune inflammation such as phlyctenular keratoconjunctivitis, marginal staphylococcal keratitis, peripheral ulcerative keratitis, Mooren's ulcer, interstitial keratitis, rosacea keratitis, etc. Mooren's ulcer, which is considered one of the most severe diseases, is presented with serial photos of follow-ups within 3 years with different complications, management of the condition, and results. A severe case of rosacea keratitis associated with anterior uveitis is included in this chapter too. Thygeson's superficial punctate keratitis case is shown as well, but the disease is very rare in Middle Eastern populations. The material in this chapter also includes filamentary, neurotrophic, and exposure keratitis. A rare disorder like anesthetic abuse keratopathy, caused by topical excess use of anesthetic drops, is presented with before and after treatment photos to illustrate that the condition, if treated appropriately, can leave minimal scarring.

2012 ◽  
Vol 96 (8) ◽  
pp. 1146.3-1147
Author(s):  
Anurag Mathur ◽  
Jatin Ashar ◽  
Virender Sangwan

2019 ◽  
Vol 4 (2) ◽  
pp. 17-173
Author(s):  
Dr. Antariksh Mohta ◽  
◽  
Dr. Milind Sabnis ◽  
Dr. Hardik Kalaria ◽  
Dr. Monica Nayyar ◽  
...  

2020 ◽  
Vol 10 (3) ◽  
pp. 116-122
Author(s):  
Lylys Surjani ◽  

Mooren's ulcer is chronic ulcerative keratitis that is generally painful, progressive starting peripherally and progressing in a circular and centralized manner, either unilateral or bilateral without scleritis and without systemic disease. Mooren's ulcer mostly idiopathic. Mooren's ulcer was divided into three type which is unilateral, bilateral progressive and bilateral indolent. Initial treatment for Mooren's ulcer consists of topical corticosteroids. If corticosteroids do not control inflammation, excision of the limbal conjunctiva can be performed. This case report describes the diagnosis and management of a case of mooren's ulcer without an obvious cause. This topic is important to discuss and requires prompt and adequate management because one of the complications is perforation which can lead to blindness.


2021 ◽  
pp. 108509
Author(s):  
Hao Chi ◽  
Wenpei Hao ◽  
Xia Qi ◽  
Ting Zhang ◽  
Yanling Dong ◽  
...  

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Rana Saad ◽  
Sami Saad ◽  
Oscar Haigh ◽  
Domitille Molinari ◽  
Marc Labetoulle ◽  
...  

Abstract Background Thygeson’s superficial punctate keratitis (TSPK) is a rare and still poorly understood disease of the ocular surface, responsible for recurrent episodes of photophobia and eye pain. While TSPK is considered as a benign condition, a subset of patients has frequent recurrences or even chronic disease, two situations in which there are currently no therapeutic guidelines. We used a preexisting Facebook TSPK patient support group to assess the clinical journey and the burden of disease of TSPK. Results An online survey was sent to the patient support group. The first part of the questionnaire gathered information on demographics and the patient’s clinical journey [diagnostic modalities, symptoms, duration and frequency of recurrent episodes (RE), efficacy and tolerance to treatments]. The second part focused on quality of life (QoL) using the Ocular Surface Disease-QoL (OSD-QoL) questionnaire. Seventy-two patients out of 595 members of the support group completed the questionnaire during the 3-months study period. Eighty percent of patients developed symptoms before 30 years old, and 47% reported a delay in the diagnosis above 1 year. Sixty percent of patients reported over 5 RE yearly, and 18% of RE lasted more than 3 months. Forty percent of all patients used cyclosporine eyedrops (50% of those with > 5 episodes/year) and it was perceived as effective by 72% of these patients. The impact on daily life activities was judged as severe by 22% of patients, while 38% reported reduced professional activity and 80% were deeply saddened by their eye condition. Conclusion TSPK patients may present with frequent recurrences and/or chronic disease, that result in a severe impact on QoL, and an off-label use of topical immunomodulatory eye drops, suggesting the urgent need for controlled studies. The utility of using social networks for rare ophthalmic disease research includes, faster data collection, data from patients across the globe, and also raises relevant questions about their real needs.


2020 ◽  
pp. 147892992091294
Author(s):  
Berna Öney

The popular movements in 2011 led to many regime changes that resulted in amended or new constitutions in the Middle East and North Africa region. The constitutional debates concentrated mainly on the functions of the constitutions in authoritarian regimes, constitution-making processes, and the role of Islam during and after the uprisings. However, no research has analyzed the ideological dimensionality of the Middle Eastern and North African constitutions. By analyzing 19 newly enacted, drafted, and amended constitutions before and after the popular movements in the region, this article shows that the single ideological dimension in the constitutions can be defined by the openness of a state for liberal and modern values. This ideological dimension encompasses all the regional political debates on the political regime dynamics, the inclusion of rights and liberties, and the role of Islam. Besides offering an alternative typology for the constitutions in the region, this article also provides evidence for the beginning of the fourth phase of Islamic constitutionalism that merges the ideas of rule of law, which originates from democratic notions, and Islamic norms.


1921 ◽  
Vol 4 (3) ◽  
pp. 161-170 ◽  
Author(s):  
Marcus Feingold

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